Assay News and Research

RSS

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Researchers have developed a stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21) against SARS-CoV-2 infection in Syrian hamsters. They demonstrated the high therapeutic efficacy of this homotrimeric Nb, leveraging both intranasal and aerosol delivery.

26 Feb 2021

Researchers use Doppler to look inside living cells, track their metabolic activity

Doppler radar improves lives by peeking inside air masses to predict the weather. A Purdue University team is using similar technology to look inside living cells, introducing a method to detect pathogens and treat infections in ways that scientists never have before.

26 Feb 2021

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

The first instance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Austria was observed in the Ski resort Ischgl in early March 2020. Later, the virus spread across Austria and other countries in Northern Europe.

25 Feb 2021

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.

25 Feb 2021

Study reports lasting immune response in convalescent COVID-19 patients

Researchers report the cellular immune response of convalescent patients in Germany, who recovered from mild or moderate infection compared to that of healthy people with no history of COVID-19.

25 Feb 2021

Novel single-particle digital assay using plasmonic nanobubbles

An interdisciplinary team from the University of Texas applied DIAMOND to the respiratory syncytial virus (RSV) diagnostics and demonstrated that DIAMOND is 150 times more sensitive than commercial lateral flow assays. They found that the measurements are completed within 2 minutes. The results of this study are published on the medRxiv* preprint server.

25 Feb 2021

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited.

24 Feb 2021

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

One of the most performed medical diagnostic tests to ascertain the health of patients is a complete blood count, which typically includes an estimate of the hemoglobin concentration.

24 Feb 2021

Beckman Coulter Life Sciences established as first us distributor of genedrive plc COVID-19 kit

As the world continues to seek solutions in response to the coronavirus pandemic, Beckman Coulter Life Sciences announces it is the first United States distributor of the Genedrive® 96 SARS-CoV-2 kit. The agreement with the near-patient molecular diagnostics company, genedrive plc (LSE: GDR), is for distribution in the US and throughout Europe.

From Beckman Coulter Life Sciences - Flow Cytometry 23 Feb 2021

Cannabinoid receptor agonist shows potential protective effect on SARS-CoV-2-infected human heart cells

As scientists continue to search for effective antidotes to direct and indirect damage caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv* server demonstrates the potential of cannabinoid receptor agonists to alleviate myocardial damage in this condition even in the absence of any inhibitory effect on viral infection as such.

23 Feb 2021

Influenza A virus defective interfering particles against SARS-CoV-2

In the search for a broadly acting pan-specific antiviral, an interdisciplinary team from Germany tested the previously proposed (for antiviral treatment against Influenza A infections) - Influenza A virus (IAV) defective interfering particles (DIPs). The research is published online on the bioRxiv preprint server.

23 Feb 2021

Researchers develop a mathematical means of assessing COVID-19 tests' false-negative rate

Even with more than 1.5 million Americans receiving a COVID vaccine each day, officials estimate it will take many more months before enough people are protected from the deadly virus.

22 Feb 2021

Novel SARS-CoV-2 vaccine utilizes recombinant spike protein with PIKA adjuvant

The primary aim of any vaccine is to stimulate immune functions and confer long-lasting protection. A paper recently uploaded to the preprint server bioRxiv by Tong et al. (17th Feb 2021) describes a novel vaccine utilizing PIKA adjuvant and recombinant spike proteins against COVID-19 disease that promises the generation of potent neutralization antibodies, which potentially support immune responses for years.

21 Feb 2021

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

A new study reports the development of nanoantibodies (nAbs) – also called or nanobodiesTM or single-domain antibodies – that effectively bind the SARS-CoV-2 spike protein from the ancestral Wuhan variant as well as the recently detected UK and South African variants.

19 Feb 2021

Researchers use zebrafish to study cancer-immune interactions

Cancer researcher Rita Fior uses zebrafish to study human cancer. Though this may seem like an unlikely match, her work shows great promise with forthcoming applications in personalized medicine.

19 Feb 2021

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

A team of researchers used several assays, atomic force microscopy, and simulations to determine that the N501Y mutation in the virus’s receptor-binding domain (RBD) increased the interaction of the virus with the angiotensin-converting enzyme 2 (ACE2) receptor.

17 Feb 2021

Bats and pangolins in Southeast Asia harbor SARS-CoV-2-related coronaviruses, study finds

A new study has reported evidence that SARS-CoV-2-related coronaviruses (SC2r-CoVs) are circulating in bats in Southeast Asia. This has extended the geographical area where SC2r-CoVs are found, underscoring the urgency of identifying the immediate ancestor of SARS-CoV-2.

17 Feb 2021

Assay News and Research

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Researchers use Doppler to look inside living cells, track their metabolic activity

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Study reports lasting immune response in convalescent COVID-19 patients

Novel single-particle digital assay using plasmonic nanobubbles

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

Beckman Coulter Life Sciences established as first us distributor of genedrive plc COVID-19 kit

Cannabinoid receptor agonist shows potential protective effect on SARS-CoV-2-infected human heart cells

Influenza A virus defective interfering particles against SARS-CoV-2

Researchers develop a mathematical means of assessing COVID-19 tests' false-negative rate

Novel SARS-CoV-2 vaccine utilizes recombinant spike protein with PIKA adjuvant

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

Researchers use zebrafish to study cancer-immune interactions

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

Bats and pangolins in Southeast Asia harbor SARS-CoV-2-related coronaviruses, study finds

Multi-resistant bacteria continue to grow in hospital wastewater

Artemisia plant extracts show potential anti-SARS-CoV-2 activity in vitro

What are the changes in the physical phenotype of blood cells in COVID-19?

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News