immunity News and Research

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Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

SARS-CoV-2 re-infection from new variant after natural infection

Researchers survey incidences of SARS-CoV-2 infection in both care home staff and residents early in the pandemic.

7 Dec 2021

New research reveals how Europeans evolved greater resistance against anthrax

New research from the Cornell College of Veterinary Medicine has revealed how humans evolved greater resistance against anthrax multiple times during history: when they developed a diet of more ruminants, and when agricultural practices took hold.

7 Dec 2021

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

7 Dec 2021

Multiplex proteomic panel assay for assessment of disease severity and outcome prediction in COVID-19

According to the authors of a new study, multiplex protein panel assay could support clinical decision-making, guide the development of novel treatments, and expand the risk assessment procedures for COVID-19.

7 Dec 2021

Study analyzes which factors play a role when people decide for or against vaccination

Getting vaccinated against Covid-19 can play a crucial role in ending the pandemic. But too many people are rejecting the vaccination. In a large online survey in May 2021, a team from the psychology department at Ruhr-Universität Bochum (RUB) analyzed which factors play a role when people decide for or against vaccination.

7 Dec 2021

Possible impact of spike protein mutations on SARS-CoV-2 Omicron variant

The current study not only analyses the mutations in the Omicron spike variant but classifies various combinations of spike mutations into groups.

7 Dec 2021

Immune response of Pfizer vaccinees who received Moderna or Pfizer booster

A new preprint discusses the immune boost resulting from homologous or heterologous booster doses in individuals fully vaccinated with two doses of the Pfizer vaccine.

7 Dec 2021

Comparison of waning COVID-19 immunity between vaccinated and infected individuals

The current study compares the waning of immunity in infected-and-recovered vs. vaccinated cohorts.

7 Dec 2021

Risk factors for COVID-19 among US healthcare workers

Researchers from the CDC have investigated the risk posed to healthcare workers and which factors are most likely to lead to infection.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

Omicron variant increases risk of SARS-CoV-2 reinfection

New surveillance data from South Africa published in the medRxiv* preprint server suggests that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omnicron variant has the potential to escape naturally-acquired immunity. The research indicates people who previously recovered from a coronavirus disease 2019 (COVID-19) are at risk for reinfection with the Omicron variant. The results show that the risk of reinfection is greater with the Omicron variant versus Delta and Beta.

6 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

Study shows COVID booster shots work

A new study investigates uses seven different COVID-19 vaccines as the third dose to boost immunity in vulnerable patients.

6 Dec 2021

SARS-CoV-2 immune memory in mRNA vaccine recipients

Researchers measured SARS-CoV-2–specific antibody, memory B cell, and memory T cell responses in a group of healthy subjects who generated primary immune responses to two doses of mRNA vaccine compared to a group of SARS-CoV-2–recovered vaccines.

6 Dec 2021

COVID-19 vaccines shown to reduce SARS-CoV-2 infection rate in cancer patients

A study recently published in the journal JAMA Oncology has stated that coronavirus disease 2019 (COVID-19) vaccines are more than 55% effective in reducing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in cancer patients.

5 Dec 2021

UK's COVID-19 booster program accelerated, and people urged to get top-up jabs

People have been urged to get a coronavirus (COVID-19) booster vaccine to top-up their protection this winter as 20 million people in the UK are expected to have had their third jabs today (Sunday 5 December 2021).

5 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021