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Novel biomarkers required to triage and monitor severely ill COVID-19 patients

Diagnostics company SphingoTec GmbH ("sphingotec") announced today the results of a working group meeting of clinical experts that discussed the utility of sphingotec's diagnostic solutions for acute and critical care in supporting the triage, diagnosis, and management of severely ill COVID-19 patients.

18 Jun 2020

Repurposing immunosuppressants to manage COVID-19

It might seem paradoxical to suggest immunosuppression could play a role in managing COVID-19. The seemingly logical therapeutic option for this disease would be an antiviral.

18 Jun 2020

COVID-19 and blood group in aortic valve replacement

The COVID-19 pandemic has been found to cause disproportionate harm in patients with cardiovascular disease, especially among the elderly population, among other risk factors. However, a new study published on the preprint server medRxiv* in June 2020 is the first to report its clinical features in patients with aortic stenosis who have had a transcatheter aortic valve replacement (TAVR).

18 Jun 2020

Researchers solve structure of key enzyme critical for biofilm formation in fungal pathogen

Aspergillus fumigatus is a species of fungus that can cause serious illnesses in immunocompromised individuals such as those who are undergoing transplantation or cancer chemotherapy.

17 Jun 2020

Living environment correlated with reaching centenarian status

When it comes to living to the ripe old age of 100, good genes help but don't tell the full story. Where you live has a significant impact on the likelihood that you will reach centenarian age, suggests a new study conducted by scientists at Washington State University's Elson S. Floyd College of Medicine.

17 Jun 2020

Iron fortification of bouillon or stock shows potential for tackling iron deficiency

Iron fortification of food is a cost-effective method of preventing iron deficiency. But finding iron compounds that are easily absorbed by the intestine without compromising food quality is a major challenge.

17 Jun 2020

Researchers take actions to reduce hospitalizations and deaths from COVID-19

Infectious disease experts from Fred Hutchinson Cancer Research Center and UW Medicine are advocating for earlier actions to reduce hospitalizations and deaths from COVID-19.

17 Jun 2020

Nano-bio hybrid systems could deliver tumor therapy

Announcing a new article publication for BIO Integration journal. In this mini-review article the authors Yuhao Chen, Meng Du, Jinsui Yu, Lang Rao, Xiaoyuan Chen, and Zhiyi Chen from The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China and the National Institute of Biomedical Imaging and Bioengineering, Bethesda, MD, USA consider nanobiohybrids in cancer therapy.

17 Jun 2020

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Now, in new research published on the preprint server bioRxiv European scientists have performed RNA structure probing to obtain a single-base resolution secondary structure map of the full SARS-CoV-2 coronavirus genome.

17 Jun 2020

SARS-CoV-2 mutated spike proteins show variations in cell entry

A new study by Japanese scientists published on the preprint server bioRxiv* in June 2020 shows that the D614g mutation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein can enhance the infectivity of the virus while leaving it vulnerable to neutralization by antibodies.

17 Jun 2020

How antibodies neutralize SARS-CoV-2 in convalescent patients

A new study by researchers from the United Kingdom and Taiwan and published on the preprint server bioRxiv in June 2020 describes the structural basis for the neutralizing effect of the SARS-CoV-2 antibody on the virus. This also indicates a possible therapeutic molecule by identifying its binding epitope as possibly a major neutralizing site.

16 Jun 2020

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

New data from TERAVOLT, a global consortium that tracks outcomes of people with thoracic cancers affected by COVID-19, offers clues as to why they experienced a high death rate of 33% when the coronavirus swept across Europe.

16 Jun 2020

New discovery could open door to next generation malaria vaccine

In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria.

16 Jun 2020

Cholesterol levels are declining in western countries but rising in Asia

Cholesterol levels are declining sharply in western nations, but rising in low- and middle-income nations - particularly in Asia, according to a study of global cholesterol levels, which involve researchers at the University of Gothenburg.

16 Jun 2020

Awareness campaign aims to alleviate unnecessary fears about calling 9-1-1 in pandemic

As new COVID-19 cases continue to rise in 22 states and strain emergency departments nationwide, the Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report (MMWR) suggest ER visits in April were down 42% across the country compared to the same period last year.

16 Jun 2020

Life saving drug found for COVID-19 patients on ventilators

Results from Oxford University’s RECOVERY trial into existing drugs for the treatment of COVID-19 has found that dexamethasone reduced deaths by a third in ventilated coronavirus patients and by a fifth in coronavirus patients requiring oxygen. This is the first drug of its kind to be demonstrated to have a significant impact on COVID-19 mortality.

16 Jun 2020

Why improved pneumonia diagnosis is needed now more than ever

News-Medical speaks to Dr. William La Via about why improved pneumonia diagnosis is vital, especially in the wake of the COVID-19 pandemic.

16 Jun 2020

Multilevel interventions improve overall rate of HPV vaccinations

New research from Boston Medical Center shows that providing education and training to pediatric and family medicine providers about the importance of human papillomavirus vaccines, in tandem with healthcare systems changes including starting an HPV vaccination series before the age of 11, improves the overall rate of HPV vaccinations among adolescent patients.

15 Jun 2020

Inhaled steroids reduce ACE2 expression in COPD lungs

A new study by scientists at Imperial College London, University of Newcastle and Prokarium, and published on the preprint server bioRxiv* in June 2020 examines the role played by inhaled corticosteroids (ICS) in the risk of acquisition of COVID-19 infection by COPD patients.

15 Jun 2020

Genetic marker may predispose African Americans to cardiac complications from COVID-19

Nearly one out of every 10 African Americans has a genetic variant that puts them inherently at an increased risk for ventricular arrhythmias and sudden cardiac death.

15 Jun 2020