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IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

Study shows why antiretroviral therapy does not work in certain HIV patients

Increasingly, UPMC's chief of infectious diseases-;a well-regarded expert in HIV/AIDS-;is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus in check, but testing says otherwise.

6 Oct 2020

Development of a coarse-grained model of SARS-CoV-2 virion

A team of scientists of the University of Chicago and the University of California San Diego has developed a coarse-grained (CG) model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virion. The model can be used as a valuable resource to perform multiscale simulations of the SARS-CoV-2 virion. The study is currently available on the bioRxiv* preprint server.

5 Oct 2020

Study fails to establish independent risk factors for SARS-COV-2 infection in HIV patients

As the COVID-19 pandemic continues to spread worldwide, a new study published in the International Journal of Infectious Diseases in September 2020 reports that people with HIV infection are not at greater risk of COVID-19 compared to the general population.

5 Oct 2020

The implications of COVID-related sexual distancing and clinical service interruption

A recent study conducted in the Atlanta area reveals that coronavirus disease 2019 (COVID-19) related sexual distancing together with clinical service interruption for sexually transmitted diseases can potentially impact the future incidence of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). The study is currently available on the medRxiv* preprint server.

4 Oct 2020

Study reveals factors that increase risk of hospitalization and death in HIV patients diagnosed with COVID-19

Clinical trials are testing whether medications that treat human immunodeficiency virus (HIV) can also treat COVID-19, leading some patients with HIV to believe they might be protected against the coronavirus.

1 Oct 2020

A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

Discovery of high affinity binders for SARS-CoV-2 spike protein

An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.

30 Sep 2020

Methamphetamine use linked to risky sexual behavior

Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior.

30 Sep 2020

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

Science's pursuits of unraveling how human cells fight viral infections kicked into high gear in 2020 with the devastating emergence of the SARS-CoV-2 virus.

30 Sep 2020

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

A new study by researchers at the Indian Institute of Science and the University of Queensland and published on the preprint server medRxiv in September 2020 discusses using a novel tool to identify the most effective among currently known anti-SARS-CoV-2 NAbs.

29 Sep 2020

Case fatality rates for COVID-19 and health indicators

Researchers from Turkey and Switzerland collaborated to study the nation-specific case fatality rates for COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pandemic has affected around 33.5 million people worldwide and killed over 1 million making it one of the largest global health crises in recent memory.

29 Sep 2020

Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine.

29 Sep 2020

WHO offers guideline on managing pharmaceutical prices

Unaffordable prices can be one of the biggest barriers to access to pharmaceutical products. A new WHO guideline for countries on managing pharmaceutical prices aims to help governments overcome this barrier and better address national public health needs.

29 Sep 2020

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

Beyond the tragic surges in hospitalizations and deaths, the first months of the COVID-19 pandemic disrupted healthcare for people with a wide range of medical conditions - including cancer.

29 Sep 2020

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

A set of agreements to make available, for low and middle-income countries, affordable, high-quality COVID-19 antigen rapid tests were today announced by the Access to COVID-19 Tools (ACT) Accelerator.

28 Sep 2020

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

A multicenter phase 1/2a randomized, double-blinded, placebo-controlled clinical trial has been conducted recently to evaluate the safety, reactogenicity, and immunogenicity of a non-replicating adenovirus-based vaccine, namely Ad26.COV2.S against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection.

28 Sep 2020

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

The vaccine candidate produced a high level of neutralizing antibodies in animal models. Rhesus macaques immunized with the vaccine candidate showed reduced viral loads in the lungs. The research is published on the preprint server bioRxiv.

28 Sep 2020

New study highlights success of health program's clinical van and street outreach

A novel mobile health program created in early 2018 by the Kraft Center for Community Health at Massachusetts General Hospital (MGH) has proven to be an effective model for bringing opioid addiction treatment services directly to marginalized individuals, particularly the homeless, a population that faces the highest risk of near-term death from drug overdose.

26 Sep 2020

HIV News and Research

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Study shows why antiretroviral therapy does not work in certain HIV patients

Development of a coarse-grained model of SARS-CoV-2 virion

Study fails to establish independent risk factors for SARS-COV-2 infection in HIV patients

The implications of COVID-related sexual distancing and clinical service interruption

Study reveals factors that increase risk of hospitalization and death in HIV patients diagnosed with COVID-19

A detailed map of latent virus reservoir in individuals with HIV

Discovery of high affinity binders for SARS-CoV-2 spike protein

Methamphetamine use linked to risky sexual behavior

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

Case fatality rates for COVID-19 and health indicators

Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

WHO offers guideline on managing pharmaceutical prices

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

New study highlights success of health program's clinical van and street outreach

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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