Human microsomes are valuable instruments for investigating metabolite identification, response phenotyping, intrinsic clearance, and inhibition tests.
Details
Microsomes – human
BioIVT produces microsomes from a variety of tissues, including the kidney, lung, and intestine. Microsomes are made from fresh tissues to preserve the maximum level of enzyme activity.
BioIVT can generate microsomes from a variety of tissues. Inquire with Customer Service about special preparations.
Features and benefits
- Pooled: Donors are profiled before being used in the pool
- Quality: The independent quality control and assurance lab inspects microsomes to ensure their quality and uniformity
- Readily wearable: Each product is produced in large batches, allowing users to utilize the same batch of microsomes in many tests
- Customization: Microsomes can be manufactured according to client criteria such as donor demographics, vial structure, enzyme activity, large lot sizes, and tissue types
Quality
Specifications
Biohazard Information: Handle this material as if it can transmit infectious agents. Universal safeguards must be undertaken. No diagnostic technique can guarantee that the Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus, or other infectious agents are not present.
As a result, all biological products provided by BioIVT should be handled at Bio-Safety Level 2 as suggested by the CDC/NHI Manual “Biosafety in Microbiological and Biomedical Laboratories, From Potentially Infectious Human Serum or Blood Specimens.”
For in vitro usage only.
- Microsomes are delivered in 0.5 mL volumes at a concentration of 20 mg/mL in 250 mM sucrose solution.
- Kidney microsomes are provided at a protein concentration of 10 mg/mL in 250 mM sucrose buffer.
- Lung microsomes are provided at a protein concentration of 10 mg/mL in 250 mM sucrose buffer.
- Intestinal microsomes are fed with a protein concentration of 10 mg/mL in 250 mM sucrose buffer.