Genomics

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Lamin C important for keeping cell’s genetic material organized, research shows

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell's "command center" — its nucleus — is key to ensuring that DNA inside it remains orderly.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

15 Nov 2021

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

11 Nov 2021

Study highlights the need for caution while using CRISPR-based gene therapies

A comprehensive study-;conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups-;has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer.

11 Nov 2021

New study offers genetic insight into why we look the way we do

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

A world-first scientific study, published today in the New England Journal of Medicine, has shown that whole genome sequencing can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS.

10 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

New epigenetic editing technique may advance the treatment of many diseases

Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should.

9 Nov 2021

New computer program can read any genome sequence and decipher its genetic code

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

9 Nov 2021

Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), contributing as part of the 'Genetics of Osteoarthritis (GO)' consortium to the world's largest study of over 800,000 individuals, have identified genetic risk factors - variants associated with SOX5 and CHST3 genes, key regulators of the development of the intervertebral discs, to be implicated in spine osteoarthritis (OA).

8 Nov 2021

Scientists document the spread of atrial fibrillation risk gene across continents and over centuries

University of Utah Health scientists have documented the spread of a disease gene across continents and over centuries.

8 Nov 2021

Study shows how whole genome sequencing could benefit children with cancer

Unravelling the entire genetic code for each child who has been diagnosed with cancer can give a more accurate diagnosis or reveal new treatment options, according to research presented at the NCRI Festival. These are the results of a pilot study of the process known as whole genome sequencing.

8 Nov 2021

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Many people develop Alzheimer's or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

3 Nov 2021

New genetic epidemiology tool provides detailed information about viruses, coinfections

With mask wearing and social distancing on the decline and the cold and flu season upon us, researchers have developed a viral panel that enables the simultaneous testing for SARS-CoV-2 along with numerous common respiratory viruses, that tells us whether other viruses also are at play in patients hard hit by COVID.

1 Nov 2021

Genomics

Lamin C important for keeping cell’s genetic material organized, research shows

Researchers discover new gene critical for daily behavioral rhythms

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Study highlights the need for caution while using CRISPR-based gene therapies

New study offers genetic insight into why we look the way we do

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

Inhibiting epigenetic modification could be key to reducing cancer metastasis

New epigenetic editing technique may advance the treatment of many diseases

New computer program can read any genome sequence and decipher its genetic code

Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists document the spread of atrial fibrillation risk gene across continents and over centuries

Study shows how whole genome sequencing could benefit children with cancer

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

New genetic epidemiology tool provides detailed information about viruses, coinfections

Harnessing the genetics of hookworms to develop next generation of PPE for combat troops

Researchers develop eToeholds for safe, effective RNA and cellular therapies

Scientists uncover key genetic networks governing human embryonic stem cell behavior

Penn's newly created split-engineered base editors show potential for research, therapeutics

A new approach to selectively turn on gene therapies in target cells

New insight into the tremendously complex "genetic dance"

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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