Genomics

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UiO researchers find 13 special genes related to epigenetic changes in cancer samples

Abnormal epigenetic changes are observed in the development of multiple types of cancer. Researchers at Centre for Molecular Medicine Norway (UiO) found 13 special genes linked to epigenetic changes in cancer samples.

16 Jun 2022

More than 1,000 genes linked to severe COVID-19 identified

Since the start of the coronavirus pandemic, scientists and clinicians have struggled to understand why some people with the infection become seriously ill or die while others have few, if any, symptoms.

15 Jun 2022

Scientists publish a robust framework to analyze chromosomal instability in human cancers

Scientists have found a way to identify and interpret 'signatures' that reveal the complex genetic causes of some of the deadliest cancers – which often have a survival rate of less than 10%.

15 Jun 2022

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

Study sheds light on inhibition of awn elongation in sorghum

Over the years, the domestication of grasses like wheat, rice, barley, and sorghum for consumption has resulted in certain modifications to their morphology. One such modification is the partial or complete elimination of the 'awns', which are the bristle- or needle-like appendages extending from the tip of the lemma in grass spikelets.

15 Jun 2022

Chromosome organization affects evolution of DNA in archaea

The structure of how DNA is stored in archaea makes a significant difference to how quickly it evolves, according to a new study by Indiana University researchers.

14 Jun 2022

Taste-related genes may play a role in determining food choices, finds study

Preliminary findings from a new study involving more than 6,000 adults found that taste-related genes may play a role in determining food choices and could, in turn, influence cardiometabolic health.

14 Jun 2022

Accurate detection of specific genomic disorders made possible by nanopore sequencing

Using nanopore sequencing, a rapid third-generation cytogenetic analysis tool, investigators are now able to accurately detect specific genomic disorders in a fraction of the time it takes to conduct traditional and molecular cytogenetic testing.

14 Jun 2022

Evonetix appoints Colin McCracken as Chief Executive Officer

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced the appointment of Colin McCracken as Chief Executive Officer with immediate effect.

From Evonetix 14 Jun 2022

New study provides 'big picture' of the genetic landscape of Europe

A new study by RCSI University of Medicine and Health Sciences examining population genetics across Europe has analyzed the diverse ancestries of people living in the UK. This knowledge has the potential to inform future health research on genetic factors leading to disease.

13 Jun 2022

Researchers gain new insight into retroviral establishment in the koala genome

Historic virus infections can be traced in vertebrate genomes. For millions of years, these genomes have been repositories for retroviruses that incorporated their code into germline cells and were inherited as endogenous retroviruses (ERVs).

13 Jun 2022

Whole-genome sequencing can help provide an accurate diagnosis of severely ill infants

Children who are born severely ill or who develop serious illness in the first few weeks of life are often difficult to diagnose, with considerable implications for their short and longer-term care.

13 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Researchers create first comprehensive functional map of genes expressed in human cells

The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including Whitehead Institute, and was finally completed in 2003.

9 Jun 2022

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

From Curia 9 Jun 2022

Stem cell models help determine previously unknown genetic markers of glaucoma

Stem cell models of the retina and optical nerve have been used to identify previously unknown genetic markers of glaucoma, in research jointly led by scientists from the Garvan Institute of Medical Research, the University of Melbourne, and the Centre for Eye Research Australia.

9 Jun 2022

Most synonymous genetic mutations are strongly harmful, study shows

In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, the working parts of living cells.

8 Jun 2022

Genomics

UiO researchers find 13 special genes related to epigenetic changes in cancer samples

More than 1,000 genes linked to severe COVID-19 identified

Scientists publish a robust framework to analyze chromosomal instability in human cancers

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Study sheds light on inhibition of awn elongation in sorghum

Chromosome organization affects evolution of DNA in archaea

Taste-related genes may play a role in determining food choices, finds study

Accurate detection of specific genomic disorders made possible by nanopore sequencing

Evonetix appoints Colin McCracken as Chief Executive Officer

New study provides 'big picture' of the genetic landscape of Europe

Researchers gain new insight into retroviral establishment in the koala genome

Whole-genome sequencing can help provide an accurate diagnosis of severely ill infants

New machine learning algorithm finds a gene signature characteristic of tumors

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Genomic analysis provides a deeper understanding of DCIS biology

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers create first comprehensive functional map of genes expressed in human cells

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

Stem cell models help determine previously unknown genetic markers of glaucoma

Most synonymous genetic mutations are strongly harmful, study shows

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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