Genomics

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Tumor matrix profiles determine the risk and prognosis of a common type of lung cancer

Scientists at the Garvan Institute of Medical Research have identified molecular profiles of the surrounding matrix of a common type of lung cancer that might indicate which patients are likely to develop aggressive tumors.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows.

21 Nov 2022

Researchers identify a novel RSV variant associated with prolonged infection

Researchers examine pathogen or host genetic risk factors for RSV infection, as well as whether certain viral variants are associated with prolonged infection.

20 Nov 2022

New gene classifier can predict the risk of cancer cells recurring or progressing

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2022

MGI announces European launch of new MGISP-Smart 8 automated sample preparation system and empowerment program at MEDICA to further access to genomics

MGI, a company committed to building core tools and technology to lead life science, today announced the introduction of the latest MGISP-Smart 8 automated sample preparation system to Europe and the first iteration of its Empowerment Program at the MEDICA Trade Fair, taking place November 14-17 in Düsseldorf.

From MGI 17 Nov 2022

Study reveals a mechanism for mitochondrial activation via nucleoid dynamics

Mitochondria, famously known as the powerhouse of the cell, are important cellular structures that are vital for their role of generating energy. Mitochondria are "dynamic", meaning they constantly fuse together and split apart. They contain a small amount of genetic information known as mitochondrial DNA (mtDNA).

17 Nov 2022

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

16 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Multilevel Julich Brain Atlas could aid in studying psychiatric and aging disorders

The multilevel Julich Brain Atlas developed by researchers in the Human Brain Project, could help in studying psychiatric and aging disorders by correlating brain networks with their underlying anatomical structure.

16 Nov 2022

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

New guidance lays out the key elements to obtain participant consent for genomics research in Canada

How can Canada optimize the impact of human genomic sequencing to increase our understanding of disease? New guidance in CMAJ (Canadian Medical Association Journal) lays out the key elements for obtaining patient consent for researchers and policymakers in this growing field.

15 Nov 2022

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease.

15 Nov 2022

Genetic differences can affect the swimming behavior of sperm cells, study shows

The behavior of sperm cells is due, in part, to the individual DNA make-up of these cells, rather than only to the genetics of males, finds a team of scientists.

15 Nov 2022

Full-metagenome analysis helps identify depressing gut microbe

In a three-year study, researchers from Skoltech, Vavilov Institute of General Genetics of RAS, the Moscow-based Mental-Health Clinic No. 1 Named After N.A. Alexeev and Serbsky Federal Medical Research Centre of Psychiatry and Narcology have examined how gut microbes in patients with a major depressive disorder are different from those in mentally healthy people.

15 Nov 2022

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions -; such as cell types or tissues.

14 Nov 2022

Researchers provide new insights into the vexing process that makes HIV stealthy

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

14 Nov 2022

Serbia’s high-throughput genetic sequencing implementation | BGI Perspectives

On the occasion of the 17th International Conference of Genomics (ICG-17) jointly organized by BGI Genomics in Riga, Dr. Ivana Morić, a research professor from the Institute of Molecular Genetic and Genetic Engineering (IMGGE) at the University of Belgrade shared first-hand insights about the implementation of high-throughput sequencing in Serbia and its exciting future.

From BGI Genomics 14 Nov 2022

Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Researchers from The Hospital for Sick Children (SickKids) have uncovered new genes and genetic changes associated with autism spectrum disorder (ASD) in the largest autism whole genome sequencing analysis to date, providing better understanding into the 'genomic architecture' that underlies this disorder.

10 Nov 2022

Genomics

Tumor matrix profiles determine the risk and prognosis of a common type of lung cancer

MIT researchers develop new technique for genome-wide studies of the liver

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Researchers identify a novel RSV variant associated with prolonged infection

New gene classifier can predict the risk of cancer cells recurring or progressing

MGI announces European launch of new MGISP-Smart 8 automated sample preparation system and empowerment program at MEDICA to further access to genomics

Study reveals a mechanism for mitochondrial activation via nucleoid dynamics

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Multilevel Julich Brain Atlas could aid in studying psychiatric and aging disorders

Gene may play a broader role in embryonic organ development

New guidance lays out the key elements to obtain participant consent for genomics research in Canada

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Genetic differences can affect the swimming behavior of sperm cells, study shows

Full-metagenome analysis helps identify depressing gut microbe

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

Researchers provide new insights into the vexing process that makes HIV stealthy

Serbia’s high-throughput genetic sequencing implementation | BGI Perspectives

Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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