Genomics

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DTU researchers create a new tool in the fight against resistant bacteria

According to the WHO, antibiotic resistance is one of the biggest threats to public health. DTU researchers have created a new tool in the fight against resistant bacteria that, based on 214,000 microbiome samples, can create an overview of the problem across countries, people and environments.

13 Oct 2022

UQ-led study analyzes genetic variants that influence height

Children's growth will be easier to assess following a University of Queensland-led study analyzing the genetic variants that influence height.

12 Oct 2022

Precise DNA cleavage using new CRISPR-Cas approach

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies.

11 Oct 2022

KAUST research could open new avenues for cancer drug development

Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.

10 Oct 2022

Age plays a more important role than genetics in affecting gene expression profiles as we get older

Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer.

7 Oct 2022

NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

Scientists develop an unprecedented animal model to investigate Ewing sarcoma

Ewing sarcoma is the second most frequent bone tumour in children, adolescents, and young adults. There is no specific treatment for this disease and current management is still limited to surgery, radiotherapy, and chemotherapy.

7 Oct 2022

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) stem cells.

7 Oct 2022

New genetically based score could help identify young children at high risk of impulsive behavior

While not all impulsive behavior speaks of mental illness, a wide range of mental health disorders which often emerge in adolescence, including depression and substance abuse, have been linked to impulsivity. So, finding a way to identify and treat those who may be particularly vulnerable to impulsivity early in life is especially important.

7 Oct 2022

New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022

Improved brain organoids provide cellular and molecular insights into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids-;which are grown in the lab from human cells-;provide insights into the brain and uncover differences that may contribute to autism in some people.

6 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

BGI Genomics, in collaboration with Southwest University, the State Key Laboratory of Silkworm Genome Biology, and other partners, has constructed a high-resolution pangenome dataset representing almost the entire genomic content in a silkworm.

30 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Study offers a new glimpse at how DNA variants can impact the lifespan

In a new study of more than 3,000 genetically diverse mice in a multicenter, multiyear project on healthy aging, Maroun Bou Sleiman and colleagues identified several genetic loci that correlate with longevity, offering a new glimpse at how DNA variants can impact the lifespan.

29 Sep 2022

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Yourgene Health plc (“Yourgene”, AIM: YGEN), a leading international molecular diagnostics group, today announced it has received Health Sciences Authority (HSA) approval for its IONA® Nx NIPT Workflow in Singapore.

From Yourgene Health 29 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

NIH launches new program to better understand the function of every human gene

The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.

27 Sep 2022

Genomics

DTU researchers create a new tool in the fight against resistant bacteria

UQ-led study analyzes genetic variants that influence height

Precise DNA cleavage using new CRISPR-Cas approach

KAUST research could open new avenues for cancer drug development

Age plays a more important role than genetics in affecting gene expression profiles as we get older

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Scientists develop an unprecedented animal model to investigate Ewing sarcoma

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

New genetically based score could help identify young children at high risk of impulsive behavior

New platform for gene editing may change the landscape of CRISPR-based therapeutics

Improved brain organoids provide cellular and molecular insights into autism

The involvement of minor intron-containing gene-encoded proteins in viral infections

ASU scientists discover an unusual RNA biogenesis pathway

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

“Mystery gene” matures a main component of the cell skeleton

Study offers a new glimpse at how DNA variants can impact the lifespan

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Novel CRISPR-based method benefits further cancer studies

NIH launches new program to better understand the function of every human gene

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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