Genomics

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Researchers map the DNA damage in human lung cells after BaP exposure

People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene (BaP), is known to damage DNA.

22 Feb 2023

Research shows DNA methylation as a robust predictor of later life outcomes

A new study utilizing data from the Health and Retirement Study at the University of Michigan’s Institute for Social Research is offering a new look at the effects of aging and what they mean for population health.

22 Feb 2023

Present-day humans share stronger genetic ties with Neanderthals than previously thought

Like a merchant of old, balancing the weights of two different commodities on a scale, nature can keep different genetic traits in balance as a species evolves over millions of years.

21 Feb 2023

Alternative splicing plays a role in compensating for loss of gene function

Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.

21 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Fetal cell program appears to protect against acute myeloid leukemia

During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

395 genes found to be differently expressed in people with type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Scientists discover how a "poisoned" form of protein could spur cancer formation

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Beckman Coulter Life Sciences presenting at SLAS2023

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the upcoming Society for Laboratory Automation and Screening (SLAS) International Conference and Exhibition.

From Beckman Coulter Life Sciences 16 Feb 2023

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

Differences in the dietary patterns of overweight or obese children contribute to variations in the gut microbiome diversity.

16 Feb 2023

Innovative software tool assembles truly complete genome sequences from many species

National Institutes of Health researchers have developed and released an innovative software tool to assemble truly complete (i.e., gapless) genome sequences from a variety of species.

16 Feb 2023

Genomics

Researchers map the DNA damage in human lung cells after BaP exposure

Research shows DNA methylation as a robust predictor of later life outcomes

Present-day humans share stronger genetic ties with Neanderthals than previously thought

Alternative splicing plays a role in compensating for loss of gene function

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Step-by-step process of rewiring cells to generate germ cell precursors

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

First fully human ovarian organoids provide insights about female reproductive health and disease

Fetal cell program appears to protect against acute myeloid leukemia

HKU research advances understanding of the fundamental biological processes of gene regulation

Structure of DREADD designer receptor could pave the way for creating next generation tools

Research reveals regional differences in the spread of Japan's two main ancestral groups

395 genes found to be differently expressed in people with type 2 diabetes

Utilizing CRISPR to discover new therapy options for COPD

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Scientists discover how a "poisoned" form of protein could spur cancer formation

Beckman Coulter Life Sciences presenting at SLAS2023

Differences in gut microbiome diversity attributed to dietary patterns in children with obesity

Innovative software tool assembles truly complete genome sequences from many species

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