Genomics

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A single gene can control brain cell growth in humans, research shows

Controlling how cells grow is fundamental to ensuring proper brain development and stopping aggressive brain tumors.

19 Mar 2022

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

18 Mar 2022

New virus-based approach for measuring variations in gene regulatory elements

Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

18 Mar 2022

Research demonstrates within-host seasonal immunity

Researchers investigate the association between seasonal flu changes and gene expression to determine the ‘within-host’ immunity concept.

17 Mar 2022

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

Mayo Clinic researchers report differences in genomic data quality among racial groups

Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas.

17 Mar 2022

Researchers identify a gene that could prevent Parkinson’s disease

Parkinson's disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons.

17 Mar 2022

Tracking the mutating coronavirus variants

Viruses continuously and naturally evolve. To track coronavirus variants, we need to think like Darwin.

16 Mar 2022

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can have damaging effects over the medium and long term.

16 Mar 2022

Study takes a new approach to looking at de novo genetic variants in autism

About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA contributes to the development of ASD has been more of a mystery.

15 Mar 2022

First genetic rat model of Down syndrome offers better understanding of the condition

In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in Japan have genetically engineered and characterized what is believed to be the first rat model of Down syndrome.

14 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible.

12 Mar 2022

Scientists identify a new protein that turbocharges gene expression

For many years, scientists have sought to understand what happens when our genes are flipped to the "on" position. Now, scientists at the University of California San Diego and Rutgers University have identified a new protein that contributes to this important process.

11 Mar 2022

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Antibiotic-resistant bacterial infections are difficult to treat and cause more than a million annual deaths worldwide, especially in hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections.

11 Mar 2022

Novel strategy for data sharing may help better understand disease-causing genetic variants

Scientists may better understand and test for the genetic variations that cause cancer and other heritable diseases through the application of a novel strategy for securely sharing and analyzing genomic data developed at the UC Santa Cruz Genomics Institute.

10 Mar 2022

Genomics

A single gene can control brain cell growth in humans, research shows

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

New virus-based approach for measuring variations in gene regulatory elements

Research demonstrates within-host seasonal immunity

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Mayo Clinic researchers report differences in genomic data quality among racial groups

Researchers identify a gene that could prevent Parkinson’s disease

Tracking the mutating coronavirus variants

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Study takes a new approach to looking at de novo genetic variants in autism

First genetic rat model of Down syndrome offers better understanding of the condition

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

Scientists identify a new protein that turbocharges gene expression

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Novel strategy for data sharing may help better understand disease-causing genetic variants

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

CRIPSR identifies cell-type-specific ACE2 modifiers

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

A new view of SARS-CoV-2 genome structure

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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