Histology & Microscopy

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Cryogenic electron microscopy helps visualize structural details of gene regulation process

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

28 Apr 2023

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

26 Apr 2023

Study sheds light on the mechanisms behind circadian rhythms

New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.

26 Apr 2023

Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Researchers at EPFL and Vrije Universiteit Brussel have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy.

24 Apr 2023

Research reveals how a bacterial pathogen creates syringe-like structures to infect the intestines

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

20 Apr 2023

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

New AI-based method for virtual staining of histopathological tissue samples

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium. Chemical staining has been the cornerstone of studying histopathology for more than a century and is widely applied in, for example, cancer diagnostics.

18 Apr 2023

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings.

17 Apr 2023

Salk study opens an entirely new way of thinking about cognitive decline

Brains are like puzzles, requiring many nested and codependent pieces to function well. The brain is divided into areas, each containing many millions of neurons connected across thousands of synapses.

12 Apr 2023

Near-infrared photoacoustic remote sensing microscopy for noncontact imaging of lipids

Photoacoustic imaging is a cutting-edge technology that uses light and sound to create images of the inside of the body.

12 Apr 2023

Novel optical imaging approach provides four-dimensional view of cell secretions

Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

11 Apr 2023

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Esther Bullitt, PhD, associate professor of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, was awarded $1.5 million from the National Institutes of Health that will go toward the purchase of a cryogenic electron microscope.

10 Apr 2023

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

31 Mar 2023

Groundbreaking technique offers a new way to gain detailed information about organic tissues

A groundbreaking technique developed by researchers affiliated with the USC Michelson Center for Convergent Bioscience presents a new way of gathering and organizing highly detailed information about organic tissues in record time.

31 Mar 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

Renishaw is pleased to introduce fluorescence lifetime imaging microscopy (FLIM) functionality to its inVia™ confocal Raman microscope.

From Renishaw plc - Additive Manufacturing for Healthcare Applications 28 Mar 2023

Histology & Microscopy

Cryogenic electron microscopy helps visualize structural details of gene regulation process

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

Study sheds light on the mechanisms behind circadian rhythms

Previously unknown mechanisms may lead to new approaches to fight viral infections

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Research reveals how a bacterial pathogen creates syringe-like structures to infect the intestines

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

New AI-based method for virtual staining of histopathological tissue samples

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

Salk study opens an entirely new way of thinking about cognitive decline

Near-infrared photoacoustic remote sensing microscopy for noncontact imaging of lipids

Novel optical imaging approach provides four-dimensional view of cell secretions

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Groundbreaking technique offers a new way to gain detailed information about organic tissues

New microscopy method illuminates the mechanics of embryo development

Two distinct subtypes of insulin-producing beta cells identified

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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