Histology & Microscopy

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Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

Steroid hormones, to which belong sex hormones like estrogen or testosterone, are important signaling molecules and are responsible among other things for controlling female and male phenotypic sex differentiation.

27 Mar 2023

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts.

24 Mar 2023

New insights into how the brain's 'internal compass' works

Scientists have gained new insights into the part of the brain that gives us a sense of direction, by tracking neural activity with the latest advances in brain imaging techniques.

22 Mar 2023

New encoding strategy for single-cell tomograms streamlines data handling and storage

Single-cell analysis is a powerful biomedical technique used in various fields of biology and medicine to identify rare cell populations, track cell development and differentiation, understand disease mechanisms and develop personalized therapies, but it generates large amounts of data that can be difficult to manage.

22 Mar 2023

New model could make the measurement of skin barrier function easier

The skin is the primary physical barrier against harmful substances in the environment. But there is a significant difference in the protective capacity of the skin across individuals.

20 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

15 Mar 2023

Veterans’ health administration expands deployment of Mikroscan Systems

Mikroscan Technologies, innovators and manufacturers of live robotic microscopy and whole-slide imaging (WSI) systems, announces that it has expanded its relationship with the Veterans’ Administration through the multi-system sale of its SL5-20 Real-Time Telemicroscopy and Digital Pathology systems.

From Mikroscan Technologies 14 Mar 2023

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention.

10 Mar 2023

Astrocytes play a key role in motor learning

From steering a car to swinging a tennis racket, we learn to execute all kinds of skilled movements during our lives.

10 Mar 2023

Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

Super-resolution microscopy method for faster imaging of molecular structures in 3D

LMU researchers have developed a super-resolution microscopy method for the rapid differentiation of molecular structures in 3D.

10 Mar 2023

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Although electron microscopy can already reveal details as small as one nanometer, ongoing research seeks to break through barriers limiting image quality and reducing the optical dose on the samples. Aberration is a common problem in electron microscopy that can reduce the resolution and quality of the images produced.

3 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

New method enables direct observation of bee brains

An international team of bee researchers involving Heinrich Heine University Düsseldorf has integrated a calcium sensor into honey bees to enable the study of neural information processing including response to odors.

3 Mar 2023

Using the origami technique to design RNA nanostructures

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

Cryo-EM imaging reveals molecular machine’s secret weapon

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have launched dedicated to RNA research.

24 Feb 2023

EIT-based imaging technology for non-invasive anisotropic transmembrane transport of cell-spheroid

The cell membrane has numerous channels for the transport of various substances, including ions, between the cell and its environment.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Histology & Microscopy

Computational approach used to understand the mechanisms of protein folding in tauopathies

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

New insights into how the brain's 'internal compass' works

New encoding strategy for single-cell tomograms streamlines data handling and storage

New model could make the measurement of skin barrier function easier

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Veterans’ health administration expands deployment of Mikroscan Systems

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Astrocytes play a key role in motor learning

Study creates a radical new view of how immune cells recognize threats

Super-resolution microscopy method for faster imaging of molecular structures in 3D

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Gene mutation capable of regulating pain discovered

New method enables direct observation of bee brains

Using the origami technique to design RNA nanostructures

Cryo-EM imaging reveals molecular machine’s secret weapon

EIT-based imaging technology for non-invasive anisotropic transmembrane transport of cell-spheroid

HKU research advances understanding of the fundamental biological processes of gene regulation

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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