Molecular & Structural Biology

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Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

Mice study shows how working memory is maintained across interconnected brain regions

How does the brain keep in mind a phone number before dialing? Working memory is an essential component of cognition, allowing the brain to remember information temporarily and use it to guide future behavior.

3 Aug 2022

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Assistant Professor Jianhua Zhao, Ph.D., has been awarded a unique and competitive grant from the National Institute of General Medical Sciences, part of the National Institutes of Health.

2 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

Cross-validation of distance measurements in motile proteins reveals certain inconsistencies

The researchers from PD Dr. Gregor Hagelueken's group at the Institute of Structural Biology of the UKB used so-called PELDOR spectroscopy to study the movement of so-called substrate-binding proteins.

1 Aug 2022

CrestOptics’ DeepSIM super resolution confocal microscope module named by Microscopy Today as a top 10 best microscopy innovation of 2022

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, has been recognised as developing one of the ten best microscopy innovations in the 2022 Microscopy Today Innovation Awards, DeepSIM.

1 Aug 2022

Interactive effects of sexual dimorphism and ancestry influence development of the frontal sinus

Located between and above your eyebrows, the frontal sinuses develop in shapes that are as unique to each person as a fingerprint.

29 Jul 2022

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

Fuzhong Zhang, professor of energy, environmental and chemical engineering at the McKelvey School of Engineering, has developed a synthetic biology platform to produce muscle fibers that are strong, tough and can absorb energy in ways very similar to the real thing.

29 Jul 2022

AI image analysis tool enables insight creation without AI expertise

Leica Microsystems, a leader in microscopy and scientific instrumentation, has released a new version of its AI-powered image analysis solution, Aivia.

From Leica Microsystems GmbH 29 Jul 2022

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Researchers describe the evolution of the SARS-CoV-2 non-structural protein 1 (NSP1).

28 Jul 2022

Predicting viral antibody escape using pre-pandemic data

A new study reports early prediction of SARS-CoV-2 immune evasion using EVEscape.

28 Jul 2022

Researchers unravel how one gut bacterium influences immunity

From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease.

27 Jul 2022

Highly specialized T cells remain in blood 20 months after COVID-19

researchers analyze T-cell reactivity following recovery from COVID-19.

27 Jul 2022

Scientists uncover and sequence ancient herpes virus genomes that commonly cause lip sores

Ancient genomes from the herpes virus that commonly causes lip sores – and currently infects some 3.7 billion people globally – have been uncovered and sequenced for the first time by an international team of scientists led by the University of Cambridge.

27 Jul 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022

How SARS-CoV-2 Omicron spike mutations contribute to increased infectivity

Researchers study the functional impact of Omicron mutations.

25 Jul 2022

Why Omicron is more infectious than other SARS-CoV-2 variants

Researchers describe SARS-CoV-2 Omicron mutations and their impact on neutralization and infectivity.

25 Jul 2022

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that they have mapped the expression and maturation of the protein alpha-1 antitrypsin (AAT) with unprecedented clarity.

25 Jul 2022

Researchers create composite layered 2D materials using biomimetic proteins

Nature creates layered materials like bone and mother-of-pearl that become less sensitive to defects as they grow.

25 Jul 2022

Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

Molecular & Structural Biology

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Mice study shows how working memory is maintained across interconnected brain regions

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

Cross-validation of distance measurements in motile proteins reveals certain inconsistencies

CrestOptics’ DeepSIM super resolution confocal microscope module named by Microscopy Today as a top 10 best microscopy innovation of 2022

Interactive effects of sexual dimorphism and ancestry influence development of the frontal sinus

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

AI image analysis tool enables insight creation without AI expertise

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Predicting viral antibody escape using pre-pandemic data

Researchers unravel how one gut bacterium influences immunity

Highly specialized T cells remain in blood 20 months after COVID-19

Scientists uncover and sequence ancient herpes virus genomes that commonly cause lip sores

Using CRISPR to Lift the Lid on Probiotics

How SARS-CoV-2 Omicron spike mutations contribute to increased infectivity

Why Omicron is more infectious than other SARS-CoV-2 variants

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

Researchers create composite layered 2D materials using biomimetic proteins

Oligomeric molecular structure of the MOR-Gal1R complex revealed

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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