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Sharp declines in opioid production costs could reduce the price per dose

The legalization of cannabis and the arrival of nonmedical fentanyl are fundamentally changing drug markets in North America.

11 Mar 2021

Lower dose of ketamine is as effective as the standard dose to treat pain in adults

A recent Loyola Medicine study found that reducing the standard dose of IV-administered ketamine in half is as effective as the larger, standard dose in reducing pain in adults.

10 Mar 2021

Pfizer’s newest vaccine plant has persistent mold issues, history of recalls

Pfizer's management knew last year there was "a mold issue" at the Kansas facility now slated to produce the drugmaker's urgently needed covid-19 vaccine, according to a Food and Drug Administration inspection report.

10 Mar 2021

How likely is SARS-CoV-2 reinfection?

The coronavirus disease 2019 (COVID-19) pandemic has already caused over 117.6 million confirmed cases the world over. Yet, researchers debate the exact incidence of reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19’s causative pathogen.

10 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

Study provides accurate data on allergic reactions related to mRNA COVID-19 vaccines

Almost immediately after the first mRNA-based COVID-19 vaccines were authorized for emergency use and were administered to individuals outside of clinical trials, reports of anaphylaxis--a life-threatening whole-body allergic reaction--raised widespread concerns among experts and the public.

10 Mar 2021

Delaying second doses of COVID-19 vaccines has benefits, but longer-term results rely on robust immunity

Delaying second doses of COVID-19 vaccines should reduce case numbers in the near term.

10 Mar 2021

Rising cost of antiparasitic drugs in U.S increases patient costs, may reduce quality of care

New study finds the skyrocketing cost of drugs in U.S. used to treat hookworm and other soil-transmitted parasites increases patient costs, suggests decreased quality of care.

10 Mar 2021

Home delivery of HIV medicines could increase ART adherence, viral suppression

Home delivery of HIV medicines in South Africa significantly increased viral suppression compared to those who received clinical care, according to a study by researchers at the University of Washington School of Medicine.

10 Mar 2021

New study assesses the effects of one versus two doses of COVID-19 vaccine

While receiving just one dose of a two-dose SARS-CoV-2 vaccine tends to decrease infections in the short-term if it produces a strong immune response, it may increase the potential for the virus to "escape" therapies in the longer-term if one-dose vaccinal immunity is weak.

9 Mar 2021

Researchers report zoonotic spillover of adapted SARS-CoV-2 from minks to humans

In a recent report made available on bioRxiv* preprint server, researchers from Poland and Finland reveal a spillover event of mink-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from farmed mink to humans after an extensive adaptation process.

9 Mar 2021

New academic spin-out based in Finland introduces a nasal spray vaccine against COVID

Rokote Laboratories Finland Ltd., a newly-founded academic spin-out based in Finland is working to develop and introduce to the markets a nasal spray vaccine against COVID.

8 Mar 2021

Impairments in immune response contribute to severe COVID-19

New research by a team of scientists at University Hospital RWTH Aachen in Germany and Erasmus Medical Centre in The Netherlands characterized changes in CD8+ T cells in response to SARS-CoV-2.

8 Mar 2021

FDA-approved drug has limited treatment efficacy for hypoactive sexual desire disorder

An independent analysis of the medical trials which formed the final basis of approval by the US Food and Drug Administration (FDA) strongly suggests the drug bremelanotide has very limited effectiveness as a treatment for hypoactive sexual desire disorder (HSDD) in women, and that trial participants preferred a placebo.

8 Mar 2021

New system to automatically extract adverse drug reactions from electronic health records

Patients' electronic health records convey crucial information. The application of natural language processing techniques to these records may be an effective means of extracting information that may improve clinical decision making, clinical documentation and billing, disease prediction and the detection of adverse drug reactions.

5 Mar 2021

New approach using virtual clinical trials could revolutionize drug development

New cutting-edge research undertaken at the University of Leicester could revolutionize the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials

5 Mar 2021

SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

IQWiG's new threshold proven feasible in practice for early benefit assessments of drugs

Current examples prove the feasibility of the 15 percent threshold newly defined by IQWiG for the acceptance of responder analyses in early benefit assessments of drugs.

5 Mar 2021

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing coronavirus disease (COVID-19) caused by the B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently emerged in South Africa.

4 Mar 2021

AI-based method for repurposing existing drugs into potential treatments for Alzheimer's

New treatments for Alzheimer's disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options.

4 Mar 2021

Pharmaceutical News

Sharp declines in opioid production costs could reduce the price per dose

Lower dose of ketamine is as effective as the standard dose to treat pain in adults

Pfizer’s newest vaccine plant has persistent mold issues, history of recalls

How likely is SARS-CoV-2 reinfection?

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Study provides accurate data on allergic reactions related to mRNA COVID-19 vaccines

Delaying second doses of COVID-19 vaccines has benefits, but longer-term results rely on robust immunity

Rising cost of antiparasitic drugs in U.S increases patient costs, may reduce quality of care

Home delivery of HIV medicines could increase ART adherence, viral suppression

New study assesses the effects of one versus two doses of COVID-19 vaccine

Researchers report zoonotic spillover of adapted SARS-CoV-2 from minks to humans

New academic spin-out based in Finland introduces a nasal spray vaccine against COVID

Impairments in immune response contribute to severe COVID-19

FDA-approved drug has limited treatment efficacy for hypoactive sexual desire disorder

New system to automatically extract adverse drug reactions from electronic health records

New approach using virtual clinical trials could revolutionize drug development

SARS-CoV-2 proteins are potent suppressors of innate immunity

IQWiG's new threshold proven feasible in practice for early benefit assessments of drugs

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

AI-based method for repurposing existing drugs into potential treatments for Alzheimer's

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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