Coronavirus Disease COVID 19 News and Research

Latest Coronavirus Disease COVID 19 News and Research

Furin cleavage site and D614G on SARS-CoV-2 spike evolved to balance infectivity, stability, cytopathicity

SARS-CoV-2 is the causative agent of COVID-19 disease, currently raging across the world. The virus has now infected more than 43.89 million individuals and claimed over 1.16 million lives. The study titled, "Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects," is released on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Gut's immune response to SARS-CoV-2 very different from the lung

Megan L. Stanifer et al. study the immune response in the human gut upon SARS-CoV-2 infection. The study published as a bioRxiv* preprint reveals a robust proinflammatory response: a cell type-specific or a tissue-specific regulation of interferon-mediated signaling during SARS-CoV-2 infection.

27 Oct 2020

COVID vaccine misinformation lowering people's intent to get vaccinated

A new study by researchers at the Imperial College London and the London School of Hygiene and Tropical Medicine aimed to determine how online misinformation impacts COVID-19 vaccine uptake intent. Further, the team wanted to identify socioeconomic groups at a higher risk of not getting vaccinated and those who are most susceptible to online misinformation.

27 Oct 2020

Inflammasome may play a key role in triggering immune response to cancer

The inflammasome — a protein signaling network that is activated to rid the body of virus or bacteria-infected cells — may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers.

27 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Bigger households associated with greater odds of SARS-CoV-2 transmission

Household transmission plays a pivotal role in the spread of SARS-CoV-2. The study recommends that it is essential for people to get tested immediately or as soon as symptoms appear. This way, they will take precautions to protect the other members of the family.

27 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Rapid CD169 assay for COVID-19 screening

Researchers in France have conducted a study demonstrating the sensitivity of a rapid flow cytometry assay that could be used to screen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

27 Oct 2020

Research examines COVID-19 transmission patterns in Georgia, U.S.

Researchers from Emory University and the Georgia Department of Public Health have shown that the transmission of coronavirus disease 2019 (COVID-19) in the state of Georgia earlier this year changed over time and varied by age.

27 Oct 2020

Important structures of SARS-CoV-2 PLpro protease

The pandemic of coronavirus disease 2019 (COVID-19) is changing the world like never before. This crisis is unlikely contained in the absence of effective therapeutics or vaccine.

27 Oct 2020

Research on autophagy and coronavirus, implicates ULK1

Researchers from the University of British Columbia have discovered that the betacoronavirus-encoded papain-like protease disrupts autophagy, partly by targeting ULK1. Their work is reported on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Delaying urgent health issues can be more harmful than the potential risk of COVID-19

More than half a year into the COVID-19 (coronavirus) pandemic, healthcare providers have adapted by offering virtual visits and observing strict safety measures in clinics.

27 Oct 2020

Scientists identify new therapeutic targets for SARS-CoV-2

To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.

27 Oct 2020

Study: SARS-CoV-2 virus adopts new strategy to ensure its replication, spread

Since COVID-19 began its menacing march across Wuhan, China, in December 2019, and then across the world, the SARS-CoV-2 virus has taken a "whatever works" strategy to ensure its replication and spread.

27 Oct 2020

Impact of natural and vaccine-induced immunity could shape the future trajectory of COVID-19

New research suggests that the impact of natural and vaccine-induced immunity will be key factors in shaping the future trajectory of the global coronavirus pandemic, known as COVID-19.

27 Oct 2020

Lung biomarkers may predict severe COVID-19

Two University of New Mexico researchers postulate certain specific biomarkers' relevance in predicting the potential for progression to severe COVID-19 in a paper published on the preprint server bioRxiv*

27 Oct 2020

Frequent testing and isolation/quarantine essential to contain COVID-19

A recent study by researchers at Virginia Tech and Central China Normal University published on the preprint server medRxiv in October 2020 discusses the various interventions required and the level of control required, whether to flatten the curve or reduce the case number.

27 Oct 2020

Real-time tracking system shows rise in suspected opioid overdose deaths after COVID-19's arrival

COVID-19 may dominate the headlines. But another epidemic that was already raging before it arrived has flared up in recent months, too, according to new University of Michigan data.

27 Oct 2020

Fear and isolation drives PTSD among health/social workers in COVID-19

A new study, published on the preprint server medRxiv* in October 2020, identifies the factors that predict distress in HSCW and emphasizes the importance of adequate supplies of personal protective equipment (PPE).

27 Oct 2020

Researchers identify effective way to protect vulnerable people from COVID-19

T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according to a new study published Oct. 26 in Blood.

27 Oct 2020