Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Single Sputnik V vaccine dose elicits robust immune response in previously infected individuals

A new preprint research paper posted to the medRxiv server describes successful immunization of the vaccinated population with a single dose of the Russian-made Sputnik V vaccine.

29 Mar 2021

Linear epitope mapping of the SARS-CoV-2 spike protein

The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the primary target of many drug discovery efforts and is similarly utilized in each of the approved COVID-19 vaccines to elicit the generation of anti-spike protein antibodies, thereby granting immunity.

28 Mar 2021

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Several companies and research groups have been searching for suitably docking ligands that inhibit the function of this protein. In a research paper recently published to the Springer journal VirusDisease by Surya & Praveen (March 6th, 2021) in silico docking simulations towards 3CLpro have been performed, focusing in particular on natural products obtained from the plant Boerhavia diffusa.

28 Mar 2021

Combined clinical and genomic data better predicts COVID-19 severity

The current COVID-19 outbreak is one of the worst pandemics in history and has claimed millions of lives across the globe, overwhelmed healthcare systems, and created unprecedented socio-economic ramifications.

28 Mar 2021

Antibody agents effective at neutralizing European, South African, and United States SARS-CoV-2 variants

Researchers in the United States have demonstrated the effectiveness of three antibody agents at neutralizing recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

28 Mar 2021

New SARS-CoV-2 genome variants identified in US mink

Researchers in Canada have discovered two novel variants in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene sequences collected from mink in the United States.

28 Mar 2021

Research finds polymerase of SARS-CoV-2 can adopt an alternative structure

New research by German scientists has uncovered another form of coronavirus polymerase. The current polymerase thought to be used for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral RNA-dependent RNA polymerase (RdRp) for replication and transcription. It contains a monomeric enzyme with the catalytic subunit nsp12, two copies of subunit nsp8, and one copy of subunit nsp7.

28 Mar 2021

mRNA vaccines and monoclonal antibodies protect against new NYC-B.1.526 variant

A new fast-spreading severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant called B.1.526 recently emerged in New York City and caused concerns for its potential to resist the immune system.

28 Mar 2021

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

In a recent article currently available on the bioRxiv* preprint server, researchers from Belgium and the U.S. demonstrated a robust replication model for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates in primary human epithelial cells at the air-liquid interface and appraised the antiviral effect of selected viral replication inhibitors.

28 Mar 2021

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

In a paper recently uploaded to the preprint server medRxiv*, clinical and demographic data from across the UK is compared to viral genome sequence data, identifying trends amongst the population affected, and across SARS-CoV-2 strains.

26 Mar 2021

Longitudinal study of SARS-CoV-2 antibodies following vaccination

A longitudinal study of IgG antibody levels in vaccinated healthcare workers was recently uploaded to the preprint server medRxiv*, suggesting that IgG levels could be a reliable indicator of successful vaccination.

26 Mar 2021

Testing unavailability may influence public behaviors and facilitate SARS-CoV-2 transmission

A team of scientists from the University of California, Los Angeles, USA, recently conducted a survey investigating the association between availability of testing facilities and COVID-19-related behavioral aspects. Their findings reveal that testing unavailability independently influences certain COVID-19-related behaviors that may increase the risk of SARS-CoV-2 transmission.

26 Mar 2021

Occupation not a reason for high COVID-19 rates among immigrants in Norway, finds study

A new study has found that the disproportionate rate of COVID-19 among immigrant groups in Norway may not be a result of occupational risks.

26 Mar 2021

New mathematical model identifies role of super-spreaders in SARS-CoV-2 variant emergence

Researchers have developed a new mathematical model which helps characterize factors responsible for the emergence of new SARS-CoV-2 variants and their predominance.

26 Mar 2021

COVID-19 pandemic lockdown measures have caused body weight increases in U.S., finds study

Researchers from the University of California, San Francisco, studied the body weight changes of a longitudinal cohort during the initial SIP (shelter-in-place) orders to better understand the possible downstream health implications of a prolonged SIP. They found a significant increase in body weight over the post-SIP period at a rate of roughly a pound and a half weight gain per month following SIP.

26 Mar 2021

COVID-19 long haulers report persistent neurological symptoms

Researchers at Northwestern University, USA, analyzed "long hauler" patients whose symptoms lasted at least six weeks. They found persistent neurological symptoms, including brain fog and headache.

26 Mar 2021

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Researchers at the University of Manchester, UK, aimed to systematically review the literature to provide evidence on SARS-CoV-2 and audio-vestibular symptoms. They found that COVID-19 has been tied to hearing loss, vertigo, and tinnitus.

26 Mar 2021

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

A team of scientists from the USA and Canada recently characterized the cross-neutralizing potency of anti-SARS-CoV-2 antibodies isolated from COVID-19 patients. The findings reveal that some of the isolated antibodies targeting the spike RBD and the S2 subunit are capable of cross-neutralizing other members of the human beta-coronavirus family.

25 Mar 2021

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

The scientific consensus is that safe and highly effective vaccines are required to end the ongoing pandemic of coronavirus disease 2019 COVID-19, caused by SARS-CoV-2. A new study describes a new vaccine that presents two viral antigens to the human immune system, in order to elicit a more efficacious response.

25 Mar 2021

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

A new study, which was released on the bioRxiv* preprint server, shows the differential effect that a standard vaccine protocol may have on individuals, based on their history of prior infection with the virus.

25 Mar 2021

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Single Sputnik V vaccine dose elicits robust immune response in previously infected individuals

Linear epitope mapping of the SARS-CoV-2 spike protein

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Combined clinical and genomic data better predicts COVID-19 severity

Antibody agents effective at neutralizing European, South African, and United States SARS-CoV-2 variants

New SARS-CoV-2 genome variants identified in US mink

Research finds polymerase of SARS-CoV-2 can adopt an alternative structure

mRNA vaccines and monoclonal antibodies protect against new NYC-B.1.526 variant

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

Longitudinal study of SARS-CoV-2 antibodies following vaccination

Testing unavailability may influence public behaviors and facilitate SARS-CoV-2 transmission

Occupation not a reason for high COVID-19 rates among immigrants in Norway, finds study

New mathematical model identifies role of super-spreaders in SARS-CoV-2 variant emergence

COVID-19 pandemic lockdown measures have caused body weight increases in U.S., finds study

COVID-19 long haulers report persistent neurological symptoms

Can COVID-19 cause hearing loss, vertigo, and tinnitus?

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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