T Cell News and Research

Latest T Cell News and Research

Pfizer-BioNTech COVID-19 vaccine effective against variants, study shows

Researchers at NYU Grossman School of Medicine in New York have conducted a study demonstrating the effectiveness of the Pfizer-BioNtech BNT162b2 vaccine against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

9 Feb 2021

MSK researchers report an underlying cause of COVID brain

One of the dozens of unusual symptoms that have emerged in COVID-19 patients is a condition that's informally called "COVID brain" or "brain fog."

9 Feb 2021

New drug shows promise in treating pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology.

9 Feb 2021

Researchers create bone replicas using a hot nano-chisel

A holy grail for orthopedic research is a method for not only creating artificial bone tissue that precisely matches the real thing, but does so in such microscopic detail that it includes tiny structures potentially important for stem cell differentiation, which is key to bone regeneration.

9 Feb 2021

New discovery revises the ‘text book view’ of cell migration

Research groups at University of Helsinki and Institut Jacques Monod, Paris, discovered a new molecular mechanism that promotes cell migration.

9 Feb 2021

People with dementia found to have significantly increased risk for COVID-19

A study led by Case Western Reserve University researchers found that patients with dementia were at a significantly increased risk for COVID-19-;and the risk was higher still for African Americans with dementia.

9 Feb 2021

Metal-containing radiopharmaceuticals could improve access to diagnostic imaging of AD

A team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State University and D. Mendeleev University of Chemical Technology of Russia has summarized metal-containing diagnostic agents for positron emission tomography (PET), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT) imaging of Alzheimer's disease (AD).

9 Feb 2021

Researchers develop self-assembling nanoparticle SARS-CoV-2 vaccines

Researchers in China have developed three SARS-CoV-2 nanoparticle vaccines, containing receptor-binding domain (RBD) trimer, S1 trimer, and ectodomain (ECD) trimer, respectively. To do this, they have used Ferritin nanoparticle self-assembly technology.

9 Feb 2021

Study reveals new molecular mechanism linked to severe anaphylaxis

Anaphylaxis is a systemic allergic reaction that can affect the skin, the gastrointestinal tract, the respiratory system and the cardiovascular system.

9 Feb 2021

Smell and taste loss symptoms associated with robust SARS-CoV-2 antibody response in new study

Researchers in Italy report a correlation between the loss of smell and taste and an observed persistence or rise in antibody levels at five months after infection.

9 Feb 2021

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

A new study provides direct evidence that the oligosaccharides attached to the viral surface spike protein are essential for viral infection, offering new approaches to preventive and therapeutic drugs.

9 Feb 2021

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

Researchers report the association of subgenomic RNA (sgRNA) production, the structural differences between sgRNA variants, and clinical severity in 81 clinical specimens obtained from both asymptomatic and symptomatic individuals with SARS-CoV-2 infection.

9 Feb 2021

Emergence and transmission of UK SARS-CoV-2 variant in the US

Researchers describe the impending rise to dominance of the B.1.1.7 (UK) variant in the US. Understanding this development will help to shape preventive action to reduce the infection and mortality rates.

9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

Study identifies major flaws in iBMEC-based models of the blood-brain barrier

A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.

9 Feb 2021

Immune responses to insulin could help identify individuals at risk for developing type 1 diabetes

Researchers from the Barbara Davis Center for Childhood Diabetes at the University of Colorado Anschutz Medical Campus have found that immune responses to insulin could help identify individuals most at risk for developing Type 1 diabetes.

9 Feb 2021

Study explores how membraneless organelles form and organize themselves

In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.

9 Feb 2021

Simple blood test can detect a wide range of diseases

In diagnostic medicine, biopsies, where a sample of tissue is extracted for analysis, is a common tool for the detection of many conditions. But this approach has several drawbacks - it can be painful, doesn't always extract the diseased tissue, and can only be used in a sufficiently advanced disease stage, making it, in some cases, too late for intervention.

9 Feb 2021

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

World health experts have long suspected that the incidence of COVID-19 has been higher than reported. Now, a machine-learning algorithm developed at UT Southwestern estimates that the number of COVID-19 cases in the U.S. since the pandemic began is nearly three times that of confirmed cases.

8 Feb 2021