Medical Thought Leaders

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News Medical's "Thought Leaders" series is a selection of articles written by national and international experts and trusted advisers in health and medicine. All the articles are written by experts who have been invited as recognised leaders in their fields to provide a "state of the art" contribution.

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature.

From Bruker BioSpin - NMR, EPR and Imaging 30 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Unseen health risks of aortic stenosis: an interview with Dr Shelley Rahman Haley

Aortic stenosis means narrowing of the aortic valve, which is the out flow valve from the left ventricle, the pumping chamber of the heart. This is the valve which opens to allow blood to flood out of the heart and all-round the body.

22 Jun 2016

Zika protection whilst traveling: an interview with Dr Crystal Aguh

The majority of the countries that are affected by the Zika virus are in the Caribbean. Many of the Caribbean Islands, including large islands such as Jamaica, Dominican Republic, Barbados and US Virgin Islands, as well as Mexico and other countries in Central and South America are affected.

16 Jun 2016

How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance.

15 Jun 2016

Using Spectral Imaging to Study Brain Tumors in 3D

I’m a biophysicist at the University of Bordeaux and I mainly work on bio-imaging methods in the cancer laboratory research facility, mostly for brain cancers.

From Daylight Solutions Inc 13 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin - NMR, EPR and Imaging 9 Jun 2016

Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Otosclerosis is a common cause of hearing loss, particularly amongst young adults. It normally starts in their 20s or 30s and it affects about 1 in 200 hundred people. In the UK, about 300,000 people are affected by the condition.

7 Jun 2016

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Cryptococcus is a fungus found in the environment throughout the world that is able to cause disease in humans. While most fungal pathogens don’t receive as much press as their bacterial or viral counterparts, they can be just as deadly.

1 Jun 2016

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

We actually normally refer to this as whole-specimen imaging of breast tissue.

From Huron Digital Pathology 24 May 2016

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

The most recent complete data for England (2014/15) shows an average uptake of the guaiac Faecal Occult Blood Tests (gFOBT) from those invited by the NHS Bowel Cancer Screening Programme (BCSP) of 58.22%.

23 May 2016

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

The hygiene hypothesis refers to the idea that decreased exposure to certain infectious agents (because of better hygiene) is the reason why we have seen an increase in inflammatory diseases in the developed world.

17 May 2016

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations.

16 May 2016

Medical Thought Leaders

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Unseen health risks of aortic stenosis: an interview with Dr Shelley Rahman Haley

Zika protection whilst traveling: an interview with Dr Crystal Aguh

How can we defeat drug resistance? An interview with Dr Grania Brigden

Using Spectral Imaging to Study Brain Tumors in 3D

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

Unlocking the dark proteome: an interview with Dr Kriwacki

Could oral supplements affect teenage behavior? An interview with Prof. Stein and Dr Tammam

Digital health: putting patients at the center. An interview with Roz Davies

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

Finding treatments for rare diseases: an interview with Dr Richard Thompson

Liposuction to manage lymphedema? An interview with Professor John Boyages

Advances in telemedicine: an interview with Dr Ameet Bakhai

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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