immunity News and Research

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Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

A new study found that applying pan-sarbecovirus nanobodies shows a strong affinity toward all sarbecovirus clades and neutralized SARS-CoV-2 receptor binding domains

4 Jan 2022

New insights into how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

SARS-CoV-2 spike T cell responses from vaccines or infection remain robust against Omicron

In a new study, a team of researchers from multi-national institutions discovered that 70-80% of CD4 and CD8 T cell responses to spike were consistent across research groups. Moreover, although having far more mutations, the magnitude of Omicron cross-reactive T cells was comparable to that of the Beta and Delta variants.

3 Jan 2022

Production of molecular probes of spike and subdomains for all SARS-CoV-2 variants

Researchers designed molecular probes of diverse SARS-CoV-2 variants and evaluated their antibody binding specificity.

3 Jan 2022

Modeling shows SARS-CoV-2 Omicron will place a severe burden on UK's health services

Researchers use data and a mathematical model to determine the impact of the SARS-CoV-2 Omicron variant on future risk of infection.

3 Jan 2022

T-cell responses to SARS-CoV-2 Omicron variant confer protection to vaccinated individuals

Researchers ascertain whether the SARS-CoV-2 Omicron variant evades cellular immunity.

3 Jan 2022

Minimal nAb titers against Omicron in the elderly after 3rd dose

Researchers measured titers of cross-protective neutralizing antibodies against SARS-CoV-2 after they had received a third booster dose.

3 Jan 2022

SARS-CoV-2 Omicron study on hamsters, shows virus results in a less severe disease

Researchers investigate the ability of immunity acquired from SARS-CoV-2 wild-type infection to protect against the Omicron variant in Syrian hamster models.

3 Jan 2022

NAbs activity against SARS-CoV-2 variants, including Omicron, in an elderly vaccinated cohort

Researchers investigate the neutralizing antibody activity against different variants of SARS-CoV-2 in fully immunized elderly individuals.

3 Jan 2022

Study shows structural and functional aspects of antibody neutralization of SARS-CoV-2 Omicron variant

Researchers investigated the potency of trimeric human nephrocystin SH3, TriSb92, a domain-derived antibody, against a conserved region in the receptor-binding domain (RBD) of the spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

31 Dec 2021

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

New evidence implies that the Omicron variant may cause a less severe and/or faster recovery from clinical COVID-19 disease.

31 Dec 2021

Omicron infection induces cross-reactive immune responses

New research revealed that vaccine-breakthrough infections might elicit cross-reactive bNAbs against all variants of concern.

31 Dec 2021

SARS-CoV-2 omicron variant may be less severe than the delta variant

A new study reveals that omicron infections in South Africa are associated with lower rates of hospital admissions and lower disease severity compared to beta and delta infections.

31 Dec 2021

A reliable assessment of COVID-19 vaccine protection duration

Researchers from the University of North Carolina, University of Washington, and the US Food and Drug Administration propose fitting a Cox model with two time indexes, the event times measured from the start of the study in calendar time and the log hazard for the vaccine effect.

30 Dec 2021

How much do mutations reduce vaccine effectiveness in the Omicron variant?

In new research, scientists from Adaptive Biotechnologies have been investigating the impact of spike protein mutations on vaccine efficiency for the Omicron variant. The study is currently available on the medRxiv* preprint server while awaiting peer review.

30 Dec 2021

Vaccine-induced T-cells vs. Omicron well preserved compared with all variants

A team of international scientists has recently revealed that T cell responses induced by coronavirus disease 2019 (COVID-19) vaccines are able to cross-recognize different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently available on the bioRxiv* preprint server.

30 Dec 2021

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

Antibody neutralization of SARS-CoV-2 Omicron variant via BNT162b2 vaccine booster dose

New study findings highlight the need for a rapid booster vaccine campaign to prevent COVID-19 caused by the Omicron variant since the neutralization of Omicron by the two-dose BNT162b2 vaccine is not effective in controlling the spread of the infection.

30 Dec 2021

Study shows varying population immunity against SARS-CoV-2

Researchers analyzed the combined distribution of COVID-19 vaccination and prior SARS-CoV-2 infection in each state and county in the US since the beginning of the COVID-19 epidemic to estimate the changes in the population immunity during this period.

30 Dec 2021

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

A new study suggests that RZV may elicit durable innate immune responses in the elderly conferring heterologous protection against COVID-19. .

30 Dec 2021

immunity News and Research

Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

New insights into how tiny bacteria from the environment have adapted to live inside humans

SARS-CoV-2 spike T cell responses from vaccines or infection remain robust against Omicron

Production of molecular probes of spike and subdomains for all SARS-CoV-2 variants

Modeling shows SARS-CoV-2 Omicron will place a severe burden on UK's health services

T-cell responses to SARS-CoV-2 Omicron variant confer protection to vaccinated individuals

Minimal nAb titers against Omicron in the elderly after 3rd dose

SARS-CoV-2 Omicron study on hamsters, shows virus results in a less severe disease

NAbs activity against SARS-CoV-2 variants, including Omicron, in an elderly vaccinated cohort

Study shows structural and functional aspects of antibody neutralization of SARS-CoV-2 Omicron variant

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

Omicron infection induces cross-reactive immune responses

SARS-CoV-2 omicron variant may be less severe than the delta variant

A reliable assessment of COVID-19 vaccine protection duration

How much do mutations reduce vaccine effectiveness in the Omicron variant?

Vaccine-induced T-cells vs. Omicron well preserved compared with all variants

SARS-CoV-2 infection and immunity in pregnancy and fetal development

Antibody neutralization of SARS-CoV-2 Omicron variant via BNT162b2 vaccine booster dose

Study shows varying population immunity against SARS-CoV-2

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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