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Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Nearly one third of UK's hospitalized COVID-19 patients readmitted

In a recent medRxiv preprint paper, researchers from the UK discussed how they determined organ impairment rates post recovery from COVID-19-related hospitalization and compared the results with that in a control group.

20 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

Patients fend for themselves to access highly touted covid antibody treatments

By the time he tested positive for covid-19 on Jan. 12, Gary Herritz was feeling pretty sick. He suspects he was infected a week earlier, during a medical appointment in which he saw health workers who were wearing masks beneath their noses or who had removed them entirely.

20 Jan 2021

Studies evaluate ovarian cancer surgery outcomes and clinical standards

These studies were supported financially by the Medtronic Chair in Surgical Training and Research and a research grant from the Carlos III-FEDER Institute of Health.

20 Jan 2021

Age is a key factor in sex-related outcomes after heart attack, indicates study

Approximately 1.5 million heart attacks and strokes occur every year in men and women in the U.S. Sex and age play a large part in who experiences a heart attack, the methods used to treat these heart attacks, and the eventual post hospital outcomes of the people who experience heart attacks.

20 Jan 2021

Study: Menopause symptoms are worse for women with premature ovarian insufficiency

Hot flashes, insomnia, and vaginal dryness are commonly reported symptoms that accompany the menopause transition.

20 Jan 2021

Sex disparity is not a risk factor for stroke mortality

An analysis of data collected from patients treated for ischemic stroke at Geisinger shows no disparity in outcomes based solely on sex.

19 Jan 2021

Unique Ohio State-led support program shows reduction in adverse pregnancy outcomes

New research suggests a unique program called Moms2B at The Ohio State University Wexner Medical Center shows a reduction in adverse pregnancy outcomes in communities disproportionately affected by these public health issues.

19 Jan 2021

On Trump’s last full day, nation records 400,000 covid deaths

While millions wait for a lifesaving shot, the U.S. death count from covid-19 continues to soar upward with horrifying speed.

19 Jan 2021

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

A new study by researchers at Northwestern University Feinberg School of Medicine, USA, shows that antibiotic regimens for critically ill COVID-19 patients with bacterial superinfections may be promoting an unnecessarily high.

19 Jan 2021

FIT test can help identify people with higher risk of colorectal cancer

New research has demonstrated that a simple, cheap test can help identify who is at risk of developing colorectal cancer, aiding early diagnosis and potentially saving lives.

19 Jan 2021

Using 'federated learning' to enhance predictions of COVID-19 outcomes

Mount Sinai researchers have published one of the first studies using a machine learning technique called "federated learning" to examine electronic health records to better predict how COVID-19 patients will progress.

18 Jan 2021

Study finds new evidence about the positive role of androgens in breast cancer treatment

Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

18 Jan 2021

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Researchers find that the presence of SARS-CoV-2's genetic material in the serum of positive patients could be a sturdy biomarker for predicting COVID-19-related mortality.

18 Jan 2021

Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

A team of scientists from the United States and Sweden has recently demonstrated that increased levels of a proinflammatory cytokine, angiopoietin-2, is responsible for hypercoagulation observed in severe COVID-19 patients.

18 Jan 2021

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

A recent study conducted by Austin Health, Australia, has revealed that the serum level of procalcitonin can be a strong indicator of bacterial co-infection with COVID-19.

18 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

What are the key factors and impact of interventions in England’s COVID-19 epidemic?

Researchers from Imperial College London provide a mathematical model to help understand how SARS-CoV-2, the causative pathogen of (COVID-19), spread across England in the first two waves of the epidemic, and the effect of various interventions by the government.

18 Jan 2021

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

A recent study by US researchers shows how the 501Y.V2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by several mutations, is able to escape neutralization by present first-wave anti-SARS-CoV-2 antibodies and potentially re-infect COVID-19 convalescent individuals.

17 Jan 2021

Mortality News and Research

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Nearly one third of UK's hospitalized COVID-19 patients readmitted

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

Patients fend for themselves to access highly touted covid antibody treatments

Studies evaluate ovarian cancer surgery outcomes and clinical standards

Age is a key factor in sex-related outcomes after heart attack, indicates study

Study: Menopause symptoms are worse for women with premature ovarian insufficiency

Sex disparity is not a risk factor for stroke mortality

Unique Ohio State-led support program shows reduction in adverse pregnancy outcomes

On Trump’s last full day, nation records 400,000 covid deaths

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

FIT test can help identify people with higher risk of colorectal cancer

Using 'federated learning' to enhance predictions of COVID-19 outcomes

Study finds new evidence about the positive role of androgens in breast cancer treatment

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

What are the key factors and impact of interventions in England’s COVID-19 epidemic?

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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