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T-cell response to Omicron after an mRNA COVID vaccine booster

In a recent prospective observational study posted to the medRxiv* preprint server, researchers determined Omicron variant-associated T cell responses before and after a third dose of messenger ribonucleic acid (mRNA) vaccination against coronavirus disease (COVID-19) in anti-CD20-treated multiple sclerosis (MS) patients.

22 Dec 2021

More breakthrough infections but less severe COVID-19 with Omicron

In a recent study posted to the bioRxiv* pre-print server, an international team of researchers reported the occurrence of coronavirus disease 2019 (COVID-19) breakthrough infections (BTIs) among health care workers (HCWs) participating in a phase III vaccine trial in Sisonke, South Africa.

22 Dec 2021

Infect, replicate, and rapidly mutate: Computational virus modeling study

A new bioRxiv* preprint study led by Barbara A Jones of IBM Research-Almaden in San Jose, California, used computational modeling to investigate how viruses rapidly mutate as well as how they respond or adapt to different host conditions. They observed a range of behaviors from glassy dynamics, bimodal quasispecies distributions, and periodic steady states.

22 Dec 2021

Protein-based nanoparticle vaccines for protection against SARS-CoV-2

A recent review article discusses recent advances in protein-based nanoparticle vaccines against SARS-CoV-2.

22 Dec 2021

COVID can affect sperm quality for three months

Researchers determine whether SARS-CoV-2 could cross the blood-testis barrier and be detected in human semen after infection.

22 Dec 2021

How COVID vaccines protected Americans against the Delta variant

A new study analyzed the COVID-19 breakthrough case and death rates among fully vaccinated individuals who were 12 years of age or above.

22 Dec 2021

rVSV-based bivalent vaccine against SARS-CoV-2 delta variant and influenza

Researchers developed four distinct recombinant vesicular stomatitis virus (rVSV)-based bivalent vaccines against SARS-CoV-2 and influenza virus.

22 Dec 2021

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Researchers have experimentally proved that virus-related double-stranded RNA (dsRNA) and the sites of viral RNA synthesis are associated with one another.

22 Dec 2021

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

A new study shows that although the Omicron variant exhibits significant immune escape compared to other SARS-CoV-2 variants, antibody neutralization can be largely restored with booster doses of mRNA vaccines.

22 Dec 2021

Role of novel SARS-CoV-2-derived svRNAs and the involvement of tRF in COVID-19

A new study revealed new long sv-COV-2 using T4 PNK pretreatment and qRT-PCR and also identified piRNAs and tRFs as the most abundant sncRNAs in COVID-19 positive samples.

22 Dec 2021

Omicron evades roughly twice the number of SARS-CoV-2 neutralizing antibodies than Delta

New study results highlight that Omicron has an increased affinity to ACE-2 receptors, therefore, has increased infectivity, viral load, and transmissibility compared to other variants of concern, including the Delta variant.

22 Dec 2021

Extended interval between second and third vaccination beneficial against SARS-CoV-2 Omicron variant

A new study proposes a multi-boost vaccine strategy with a longer duration between the second and third dose, as that would be beneficial in acquiring immunity against severely mutated SARS-CoV-2 variants.

22 Dec 2021

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

A new study shows that the optimization of nitazoxanide formulations may allow the review of the potential use of the drug for the treatment of SARS-CoV-2 infection.

22 Dec 2021

Scientists identify a panel of nanobodies with good neutralizing efficacy against SARS-CoV-2 variants of concern

A team of scientists from Canada has recently characterized a panel of nanobodies against the spike protein of SARS-CoV-2.

22 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Furin cleavage site similarities in SARS-CoV-2 and rodent coronavirus indicate common wildlife host

New study findings show that AcCoV-JC34 is the only luchacovirus containing a –RR-R- motif that is identical to the one found in SARS-CoV-2.

22 Dec 2021

Exploring the Mediterranean diet as a potential strategy against SARS-CoV-2

A study found that the Mediterranean diet, when combined with non-smoking and regular physical activity, can lower susceptibility to SARS-CoV-2.

22 Dec 2021

Scientists develop a detailed epidemiological model for the spread of COVID-19 in nursing homes

Researchers from TU Graz and Complexity Science Hub (CSH) Vienna have developed a detailed epidemiological model for the spread of the coronavirus in nursing homes. This enables optimal prevention strategies to be identified, as practical experience in Caritas nursing homes has shown.

22 Dec 2021

Importance of pneumococcal vaccination during the COVID-19 pandemic

A new study discusses the necessity and role of pneumococcal immunization in strengthening the global health system amid the current COVID-19 pandemic.

22 Dec 2021

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the nucleus, which is necessary for the production of new viruses.

22 Dec 2021

SARS News and Research

T-cell response to Omicron after an mRNA COVID vaccine booster

More breakthrough infections but less severe COVID-19 with Omicron

Infect, replicate, and rapidly mutate: Computational virus modeling study

Protein-based nanoparticle vaccines for protection against SARS-CoV-2

COVID can affect sperm quality for three months

How COVID vaccines protected Americans against the Delta variant

rVSV-based bivalent vaccine against SARS-CoV-2 delta variant and influenza

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

Role of novel SARS-CoV-2-derived svRNAs and the involvement of tRF in COVID-19

Omicron evades roughly twice the number of SARS-CoV-2 neutralizing antibodies than Delta

Extended interval between second and third vaccination beneficial against SARS-CoV-2 Omicron variant

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

Scientists identify a panel of nanobodies with good neutralizing efficacy against SARS-CoV-2 variants of concern

Defensosomes can act as decoys to protect against SARS-CoV-2

Furin cleavage site similarities in SARS-CoV-2 and rodent coronavirus indicate common wildlife host

Exploring the Mediterranean diet as a potential strategy against SARS-CoV-2

Scientists develop a detailed epidemiological model for the spread of COVID-19 in nursing homes

Importance of pneumococcal vaccination during the COVID-19 pandemic

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

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How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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