SARS CoV 2 News and Research

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NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

A large clinical trial, known as the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-2), is set to take place, which aims to test monoclonal antibody efficacy and safety in people who have mild or moderate COVID-19.

6 Jan 2021

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Researchers have shown that prescribing vitamin D supplementation to COVID-19 patients seems to decrease the mortality rate, the severity of the disease, and serum levels of inflammatory markers.

6 Jan 2021

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Researchers recently demonstrated that chemical agents capable of reducing disulfide (S-S) bonds can be potentially used as antiviral drugs against SARS-CoV-2, the causative pathogen of COVID-19.

6 Jan 2021

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

A new study shows the effectiveness of a novel recombinant vaccinia virus that expresses modified SARS-CoV-2 spike antigen, in preventing the replication of the virus in the respiratory tract of transgenic mice, and to prevent lethal disease.

6 Jan 2021

Are SARS-CoV-2 antibodies associated with disease enhancement?

As SARS-CoV-2 continues to wreak its havoc, antibodies that neutralize the virus and protect against infection have become an important focus of research. However, there is a concern as to whether these antibodies can actually enhance the disease.

6 Jan 2021

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

The new variant of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detected in England replicates more than two times faster than the earlier strains. This replication advantage promises to make it the dominant global variant very shortly. This finding comes from a startling preprint that appeared on the medRxiv* server in December 2020.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Researchers identify natural products with potential to disrupt viral spread

Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread.

5 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

One-third of COVID-19 survivors manifest neurological problems

In a longitudinal study recently published on the preprint server medRxiv*, Andrea Pilotto et al. find that one-third of COVID-19 infection survivors have long-term neurological manifestations after hospitalization.

5 Jan 2021

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

Researchers investigating attitudes towards vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among the UK population have found that, overall, most people were willing to accept a vaccine.

5 Jan 2021

Three teams at Binghamton University awarded grants to pursue COVID-19 research projects

The State University of New York has awarded grants of up to $10,000 to three teams at Binghamton University to pursue research projects related to COVID-19.

5 Jan 2021

COVID-19 vaccination in UK may not lead to relaxation of control measures

Researchers have warned that early relaxation of coronavirus disease 2019 (COVID-19) control measures in the UK could lead to pronounced waves of further infection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Jan 2021

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Using monoclonal antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and senescent markers, researchers provide evidence that virus-infected lung cells acquire characteristics of cellular senescence, which also leads to expression of proinflammatory cytokines.

5 Jan 2021

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

Researchers conducted a mass, asymptomatic screening of patients in dental surgeries across Scotland to assess illustrate its potential utility in curbing silent transmission.

5 Jan 2021

Copper surfaces can inactivate SARS-CoV-2 in as little as one minute, study finds

A new study by researchers at the University of Southampton, UK, has found that SARS-CoV-2 can inactivate on copper surfaces in as little as 1 minute. This is faster than the findings of previous studies in which it took as much as 4 hours before the virus was inactivated.

5 Jan 2021

Can interregional travel restrictions curb SARS-CoV-2 transmission?

A study led by Dr. Keisuke Kondo at the Research Institute of Economy, Trade and Industry, Japan, has recently developed a mathematical model to investigate the impacts of interregional mobility restriction on the transmission of SARS-CoV-2.

5 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers from Mexico demonstrate how they calculated age-stratified COVID-19 case fatality rates, years of life lost (YLL), and relative risk for 9 comorbidities and 23 comorbidity combinations in a retrospective study.

5 Jan 2021

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

By conducting a state-of-the-art interactome study between SARS-CoV-2 and host cells, researchers from the University of Texas MD Anderson Cancer Center in Houston identified 437 human proteins as the high-confidence interacting proteins – with substantial implications for understanding coronavirus disease 2019 (COVID-19) pathology and potential treatments.

5 Jan 2021

SARS CoV 2 News and Research

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

Are SARS-CoV-2 antibodies associated with disease enhancement?

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

New mathematical model proposes optimal treatment strategies for COVID-19

Researchers identify natural products with potential to disrupt viral spread

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

One-third of COVID-19 survivors manifest neurological problems

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

Three teams at Binghamton University awarded grants to pursue COVID-19 research projects

COVID-19 vaccination in UK may not lead to relaxation of control measures

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

Copper surfaces can inactivate SARS-CoV-2 in as little as one minute, study finds

Can interregional travel restrictions curb SARS-CoV-2 transmission?

A paper-based sensor for detecting COVID-19

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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