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Municipalities with low socioeconomic status in Greater Santiago have higher COVID-19 mortality

People up to age 40 living in economically depressed municipalities in the Greater Santiago, Chile, metropolitan area were three times more likely to die as a result of the infection than their counterparts in wealthier areas, researchers report in the journal Science.

28 Apr 2021

Why do we lose our sense smell/taste with COVID?

The angiotensin-converting enzyme 2 (ACE2) enzyme attached to the membranes of cells is the entry point for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They are abundantly found all over the body and most prominently in the lungs and nose.

28 Apr 2021

Neonates exposed to SARS-CoV-2 can sustain adverse health outcomes

The incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from mothers to newborns appears low and may be linked to biological as well as social factors. However, studies focusing on the factors associated with neonatal viral testing outcomes.

27 Apr 2021

SARS-CoV-2 virus neutralized with half-second exposure to very high temperature

As reported in the journal Biotechnology and Bioengineering, the team from Texas A&M University developed a simple fluidics system that measures the sub‐second heat inactivation of coronaviruses.

27 Apr 2021

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun.

27 Apr 2021

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

Researchers in Israel have shown that three national programs established by the Israeli government have successfully reduced cases of severe coronavirus disease 2019 (COVID-19) and death caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2021

Heat treatment for less than a second completely inactivates SARS-CoV-2

Arum Han, professor in the Department of Electrical and Computer Engineering at Texas A&M University, and his collaborators have designed an experimental system that shows exposure of SARS-CoV-2 to a very high temperature, even if applied for less than a second, can be sufficient to neutralize the virus so that it can no longer infect another human host.

27 Apr 2021

ANTICOV clinical trial to test new treatment for people with mild-to-moderate COVID-19 in Africa

The ANTICOV clinical trial, conducted in 13 African countries, has started the recruitment of participants to test a new drug combination, nitazoxanide + ciclesonide, to treat people with mild-to-moderate COVID-19 before their cases become severe.

27 Apr 2021

New treatment reduces the severity of ARDS in influenza-infected mice

A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study.

27 Apr 2021

Benefits of deploying the AstraZeneca vaccinations for COVID-19 greatly outweigh its risks

The AstraZeneca COVID-19 vaccine is suspected of being linked to a small number of deep vein thrombosis (DVT) cases, which recently emerged within Europe as millions of people received vaccinations. This led several countries to suspend AstraZeneca injections and investigate the causal links to DVT.

27 Apr 2021

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

A new study in the journal JAMA Network reports on the disease severity associated with some clades of the virus, from an analysis of genomes from specimens isolated in the initial phase of the pandemic.

27 Apr 2021

Israel study suggests elementary school reopenings are low-risk for COVID-19 transmission

Ever since COVID-19 first emerged with devastating ferocity, the emphasis has been on interrupting its spread until effective, safe and targeted antivirals and vaccines become available. The chief focus has been on non-pharmaceutical interventions (NPIs), including school closures, social distancing and shelter in place orders.

27 Apr 2021

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

An interesting poster, just presented at the annual meeting of the American Society for Pharmacology and Experimental Therapeutics 2021, reports an association between the use of certain heart medications and the risk of COVID-19.

27 Apr 2021

Study identifies mechanism behind SARS-CoV-2 viral protein production

A new study from German researchers examines how SARS viruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), hijack cells and reprogram them to enhance viral replication.

27 Apr 2021

What is the role of nanotechnology in the current COVID-19 outbreak?

The nanotechnology-based medicine platforms against COVID-19 bears hope for relief from the pandemic to save lives and mitigate the infection as part of a broader global public health agenda.

27 Apr 2021

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

A team of scientists recently investigated and compared the efficacy of spike-based and nucleocapsid-based COVID-19 vaccines in mice infected with SARS-CoV-2. Their findings reveal that nucleocapsid-based vaccines are effective in preventing SARS-CoV-2 infection in distal organs, such as the brain.

27 Apr 2021

Researchers develop eleven SARS-CoV-2 RBD nanobodies using computational design

To develop therapeutics that block this binding process, a team of researchers recently used an integrated computational approach to design nanobodies (Nbs) against the SARS-CoV-2 RBD, using neutralizing/monoclonal antibodies specific to RBD of the spike protein.

27 Apr 2021

Pandemic imperiled non-English speakers more than others

In March 2020, just weeks into the Covid-19 pandemic, the incident command center at Brigham and Women’s Hospital in Boston was scrambling to understand this deadly new disease. It appeared to be killing more Black and brown patients than whites. For Latinos, there was an additional warning sign: language.

27 Apr 2021

Study in Ireland identifies underlying conditions associated with severe COVID-19 outcomes

A national study of 20,000 patients conducted by RCSI University of Medicine and Health Sciences and the HSE Health Protection Surveillance Centre (HPSC) has identified the underlying conditions that are associated with more severe outcomes from COVID-19 in an Irish setting.

27 Apr 2021

New study looks at the impact of Covid-19 pandemic on UK healthcare

Just one third of people in the UK managed to access the hospital care they needed at the peak of the first wave of the Covid-19 pandemic – according to new research from the University of East Anglia.

27 Apr 2021

Disease/Infection News

Municipalities with low socioeconomic status in Greater Santiago have higher COVID-19 mortality

Why do we lose our sense smell/taste with COVID?

Neonates exposed to SARS-CoV-2 can sustain adverse health outcomes

SARS-CoV-2 virus neutralized with half-second exposure to very high temperature

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

Heat treatment for less than a second completely inactivates SARS-CoV-2

ANTICOV clinical trial to test new treatment for people with mild-to-moderate COVID-19 in Africa

New treatment reduces the severity of ARDS in influenza-infected mice

Benefits of deploying the AstraZeneca vaccinations for COVID-19 greatly outweigh its risks

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

Israel study suggests elementary school reopenings are low-risk for COVID-19 transmission

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

Study identifies mechanism behind SARS-CoV-2 viral protein production

What is the role of nanotechnology in the current COVID-19 outbreak?

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

Researchers develop eleven SARS-CoV-2 RBD nanobodies using computational design

Pandemic imperiled non-English speakers more than others

Study in Ireland identifies underlying conditions associated with severe COVID-19 outcomes

New study looks at the impact of Covid-19 pandemic on UK healthcare

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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