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Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

11 Mar 2020

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

New research reveals bias and stereotyping among clinical and research professionals who recruit patients to enroll in cancer clinical trials. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

10 Mar 2020

How effective is Gabapentin in alcohol use disorder?

A new study published in the journal JAMA Internal Medicine in March 2020 reports the striking efficacy of the drug gabapentin in helping people with alcohol use disorder (AUD) with their alcohol withdrawal symptoms.

9 Mar 2020

The research and development costs of a new drug

Many recent studies have focused on how much it costs to bring a new drug to market in the light of increasing drug prices. Estimates range from $314 million to $2.8 billion. Most of this was based on proprietary data and was, therefore, not verifiable independently, attracting much criticism.

3 Mar 2020

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma

27 Feb 2020

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide long-term benefit for patients.

27 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

Coronavirus vaccine trials commence

The coronavirus disease (COVID-19) outbreak has swept the world, killing 2,770 people and infecting more than 81,000. Amid the health crisis, scientists from across the globe are racing to develop novel therapies and vaccines in the hope of stemming the spread of the deadly virus.

26 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

26 Feb 2020

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

A randomized, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with coronavirus disease 2019 (COVID-19) has begun at the University of Nebraska Medical Center in Omaha.

25 Feb 2020

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.

24 Feb 2020

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

Oncology was the top therapy area for non-industry sponsored clinical trials in 2019, making up 25.7% of all clinical trials.

21 Feb 2020

New drug offers hope for preserving brain cells for a time after stroke

After 50 years of research and the testing of over 1,000 drugs, there is new hope for preserving brain cells for a time after stroke.

21 Feb 2020

Global study shows long-term survival benefit for a subset of patients with advanced lung cancer

According to the results of a large, global study led by Yale Cancer Center researchers, even a tiny amount of a biomarker known as PD-L1 (programmed death-ligand1) can predict a long-term survival benefit from using pembrolizumab (Keytruda).

20 Feb 2020

Scientists report promising activity of novel targeted drug in patients with advanced kidney cancer

Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma (ccRCC) in patients with metastatic disease.

13 Feb 2020

Combination of two antibiotics found to be no better than one for treating MRSA blood infections

Researchers attempting to improve the treatment for methicillin-resistant Staphylococcus aureus (MRSA) blood infections have discovered the combination of two antibiotics was no better than one, and led to more adverse effects.

11 Feb 2020

Novel injectable drug for faster healing of broken bones moves closer to clinical trials

One in three adults aged 60 and over suffering from a hip fracture dies within one year. Now, a Purdue University-affiliated startup is moving closer to the start of clinical trials for a novel injectable drug that is targeted to heal broken bones faster and strengthen weak bones.

11 Feb 2020

Study to evaluate safety of PrEP and dapivirine ring in pregnant women

A woman who is eight-months pregnant is the first participant to be enrolled into a study evaluating the safety and acceptability of two different HIV prevention approaches when used during pregnancy -- the monthly dapivirine vaginal ring, which is currently under regulatory review, and a daily antiretroviral (ARV) pill called Truvada, an approach already approved in several countries and commonly referred to as PrEP, short for pre-exposure prophylaxis.

10 Feb 2020

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Drug Trial News

Potential breakthrough in cancer immunotherapy with gasdermin E

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

How effective is Gabapentin in alcohol use disorder?

The research and development costs of a new drug

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

Chronic cough could be eased with new drug

Coronavirus vaccine trials commence

Investigational drug reduces heartburn severity in patients with refractory GERD

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

New drug offers hope for preserving brain cells for a time after stroke

Global study shows long-term survival benefit for a subset of patients with advanced lung cancer

Scientists report promising activity of novel targeted drug in patients with advanced kidney cancer

Combination of two antibiotics found to be no better than one for treating MRSA blood infections

Novel injectable drug for faster healing of broken bones moves closer to clinical trials

Study to evaluate safety of PrEP and dapivirine ring in pregnant women

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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