Molecular & Structural Biology

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High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

Cancer-causing viruses use a human protein to evade the innate immune response

The viruses Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) have been linked to several cancers.

6 Feb 2023

Cryo-EM provides new insights into the structure of the centromeric region

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

6 Feb 2023

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

Astrocytes, small star-shaped cells, play an important role in signal transmission in the brain. Since the protein Ezrin is found abundantly in astrocyte tendrils, it is presumed to play a role in brain function.

3 Feb 2023

UT Southwestern research could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

3 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.

3 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers explore a mutational signature related to molnupiravir in SARS-CoV-2 sequencing datasets.

3 Feb 2023

Partially quasi-programmed diseases can be delayed by slowing aging

A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Are menopause, aging and prostate cancer diseases?"

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

Research project aims to shed new light on how proteins in viruses bind to molecules

The way in which molecules interact forms the basis of life and treating illness. But what does it look like when a viral protein meets and binds to molecules like those found in medications? A new research project has been awarded DKK 65 million by the European Research Council and will now aim to shed light on this hitherto invisible process.

2 Feb 2023

Molecular & Structural Biology

High-fat diet allows the immune system to eliminate a parasitic worm from the intestine

Cancer-causing viruses use a human protein to evade the innate immune response

Cryo-EM provides new insights into the structure of the centromeric region

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

UT Southwestern research could lead to new ways of controlling gene regulation

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Molnupiravir-related mutational signatures among COVID-19 patients

Partially quasi-programmed diseases can be delayed by slowing aging

Improving CAR-based-immunotherapies using a molecular anchor

Research project aims to shed new light on how proteins in viruses bind to molecules

Novel tool uses AI to predict the efficacy of genome-editing repair options

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

Light-activated nanoscale drills can combat infectious fungi

Voice-activated device could make DNA handling at the laboratory safer for scientists

Highly effective detection of cancer biomarkers using CRISPR

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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