Molecular & Structural Biology

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New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

20 Jan 2023

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

20 Jan 2023

First-ever computer reconstruction replicates the exact chemical and 3D structure of a 'live' virus

An Aston University researcher has created the first ever computer reconstruction of a virus, including its complete native genome.

20 Jan 2023

New drug target for Ewing sarcoma discovered

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults.

20 Jan 2023

HKUST researchers map out the fundamental mechanisms of C.elegans Microprocessor

The study of microRNAs (miRNAs), small RNAs that play important roles in gene regulation in animals and humans alike, have long been a topic of interest to many.

19 Jan 2023

Research provides a comprehensive structural framework to design safer pain-relieving drugs

In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides.

18 Jan 2023

Study explores the role of endocannabinoids in hazardous drinking among young adults

Although heavy drinking in young adulthood increases the risk for alcohol use disorder (AUD), not all young heavy drinkers go on to develop AUD, globally the most common substance use disorder.

18 Jan 2023

New Pyk2-derived peptide inhibits breast cancer metastasis

An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory system, and form new, metastatic tumors in other parts of the body.

17 Jan 2023

Using the power of light to transform analytical workflows in the life sciences

In this interview, we speak to Svea Cheeseman at Refeyn about their SamuxMP products used for the analysis of adeno-associated viruses (AAV) capsids.

From Refeyn 17 Jan 2023

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

A new test that 'fishes' for multiple respiratory viruses at once using single strands of DNA as 'bait', and gives highly accurate results in under an hour, has been developed by Cambridge researchers.

16 Jan 2023

Researchers develop an artificial neuron closely mimicking the characteristics of a biological neuron

Researchers reported a conductance-based organic electrochemical neuron that mimicked biological signaling in neurons, especially activation/inactivation of their sodium and potassium channels.

16 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Rats and mice have been the backbone of biomedical research for decades -; including research to understand cancer and pioneer new treatments.

12 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

In this interview, News Medical speaks to Assitant Professor Ryan Jackson about his latest work, published in tandem Nature papers, detailing the discovery of a new CRISPR immune system.

11 Jan 2023

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Tau and tubulin proteins are one of the leading causes of many neurodegenerative diseases, such as Alzheimer's and Parkinson's.

10 Jan 2023

Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

In various European countries and North America, medical cannabis or medicines based on cannabinoids are authorized for therapeutic purposes.

9 Jan 2023

An updated framework for understanding the biology of the bacterial system

Nobody wants to be average. But for a long time, scientists have found it convenient to think of bacterial cells as just that: "average."

9 Jan 2023

Molecular & Structural Biology

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

First-ever computer reconstruction replicates the exact chemical and 3D structure of a 'live' virus

New drug target for Ewing sarcoma discovered

HKUST researchers map out the fundamental mechanisms of C.elegans Microprocessor

Research provides a comprehensive structural framework to design safer pain-relieving drugs

Study explores the role of endocannabinoids in hazardous drinking among young adults

New Pyk2-derived peptide inhibits breast cancer metastasis

Using the power of light to transform analytical workflows in the life sciences

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

Researchers develop an artificial neuron closely mimicking the characteristics of a biological neuron

Machine learning tools help unravel why human accelerated regions evolved so quickly

Valuable tool reveals the connections between gut microbes and the brain

New technique could overcome the delivery hurdles faced by promising mRNA therapies

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Unique mass spectrometry-based approach to study specific changes in DNA after replication

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

An updated framework for understanding the biology of the bacterial system

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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