Molecular & Structural Biology

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New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

Study offers novel insights into the elongation dynamics of eukaryotic cells

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences taking place in the ribosomes.

5 Jan 2023

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research.

5 Jan 2023

Neural networks responsible for spatial perception change in a nonlinear manner, study shows

Young children sometimes believe that the moon is following them, or that they can reach out and touch it. It appears to be much closer than is proportional to its true distance.

5 Jan 2023

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

Structure and function of a newly discovered CRISPR immune system revealed

In a rare feat, Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published not one, but two seminal papers in a top-tier, peer-reviewed journal this week.

4 Jan 2023

Researchers discover new cellular component with importance for the sense of smell

Researchers at Umeå University have discovered a previously unknown cellular component, an organelle, inside neurons that we use to perceive smell.

4 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Researchers discover new role of small RNAs in Salmonella infections

Salmonella are food-borne pathogens that infect millions of people a year. To do so, these bacteria depend on a complex network of genes and gene products that allow them to sense environmental conditions.

3 Jan 2023

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy.

2 Jan 2023

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

Molecular & Structural Biology

New research on DNA-repair enzyme could help enhance cancer drug development

Study offers novel insights into the elongation dynamics of eukaryotic cells

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Neural networks responsible for spatial perception change in a nonlinear manner, study shows

Recently discovered protein holds potential for the development of new tests for infectious diseases

Structure and function of a newly discovered CRISPR immune system revealed

Researchers discover new cellular component with importance for the sense of smell

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Salk scientists show how a microprotein can increase appetite in mice

Researchers discover new role of small RNAs in Salmonella infections

Innovations in expansion microscopy allow unprecedented view of the interior of cells

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

New insights on the circadian clock of Drosophila melanogaster

New insights into how working memory information may be held in mind

Researchers design 3D structures made of DNA

UC San Diego researchers rewrite the textbook on gene regulation

DISCO-MS technology enables the study of diseases at their earliest stages

Simple laser irradiation speeds up the detection of very small amounts of proteins

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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