Molecular & Structural Biology

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Scientists develop a single-cell chromatin atlas for the human genome

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome.

14 Nov 2021

Higher order protein catenation leads to the development of artificial antibodies

Chemical topology is a unique dimension for protein engineering. Over the past few years, the discovery of topological nontrivial proteins in nature has already revealed their many potential functional benefits, such as enhanced thermal/mechanical/chemical stability.

12 Nov 2021

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition.

12 Nov 2021

GPR126 gene may play an essential role in placental development, study reveals

Scientists working with an experimental mouse model at the Centro Nacional de Investigaciones Cardiovasculares have identified the essential role of the gene GPR126 in the development of the placenta during pregnancy.

12 Nov 2021

New study challenges the popular belief that gut microbiome drives autism

A new Australian collaborative Autism CRC study, led by Mater Research and The University of Queensland, has challenged the growing popular belief that the gut microbiome drives autism.

12 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine.

10 Nov 2021

Neurons needed for brain connections unfold at different speeds

Scientists at UNIGE show that during development, the different populations of neurons needed for connections between brain areas share similar genetic programs, but which unfold at different speeds.

9 Nov 2021

Waters and Sartorius partner to help bioprocess scientists accelerate clone selection and process development

Waters Corporation and Sartorius announced today they will partner to provide bioprocess experts with direct access to high-quality mass spectrometry (MS) data to accelerate the speed and improve the accuracy of biopharmaceutical process development.

From Sartorius 3 Nov 2021

Rice introduces new online portal to help researchers screen COVID-19 drug candidates

Rice University researchers have introduced an online portal to help researchers screen COVID-19 drug candidates that might attack specific proteins of the SARS-CoV-2 virus.

1 Nov 2021

Protein pairs assemble based on their complementary shapes

Proteins bind to one another through a complex mix of chemical interactions. What if some proteins bind due to their shapes, a much simpler process? To answer this question, researchers used Summit, the nation's fastest supercomputer, to model lock-and-key interactions.

30 Oct 2021