T Cell News and Research

Latest T Cell News and Research

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

The National Cancer Institute has granted a $2.5 million, five-year R37 MERIT Award to Dr. Bryan Burt, associate professor of surgery and chief of the Division of General Thoracic Surgery, for his research project titled, "Proteomic Determinants of Response to Checkpoint Blockade in Malignant Pleural Mesothelioma."

16 Feb 2021

Discovery opens up the possibility to predict metastases even before cancer develops

The researchers analyzed cells, mouse models, and human patient samples using biochemical, mathematical, and biophysical methods.

16 Feb 2021

Daily caffeine consumption can change the gray matter of the brain

Coffee, cola or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary.

16 Feb 2021

Top scientists, advances in analytical chemistry recognized

Each year, Pittcon provides a venue where scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy are honored.

From Pittcon 16 Feb 2021

Raman Spectroscopy: Improving the Food Production Process

News-Medical interviews Karen Esmonde-White and Ola Wesstrom from Kaiser Optical about their raman spectroscopy solutions for improving food production.

From Endress+Hauser 16 Feb 2021

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML) – called NPM1 – that could help predict survival and improve treatment response for patients whose leukemic cells bear the mutation.

16 Feb 2021

Artemisia plant extracts show potential anti-SARS-CoV-2 activity in vitro

A team of scientists from Germany and the USA recently explored the effectiveness of traditional plant medicines in treating SARS-CoV-2 infection.

16 Feb 2021

What are the changes in the physical phenotype of blood cells in COVID-19?

While primarily a respiratory illness, there are distinctive alterations in the type and number of blood cells in COVID-19. A new study by a team of researchers in Germany describes the nature of these changes.

16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Mink-derived SARS-CoV-2 mutations reduce antibody effectiveness

A new preprint research paper posted to the bioRxiv* server shows that these mutations disrupt inhibition by neutralizing antibodies, both natural and therapeutic.

16 Feb 2021

Elevated Activin A and FLRG levels correlate with worst outcomes in severe COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a "cytokine storm" in hospitalized and ICU patients. Studies have shown that the blockade of cytokine signaling and steroid treatment helps achieve positive outcomes in patients.

15 Feb 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice.

15 Feb 2021

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

In the study, published on the preprint server bioRxiv, the team evaluated the ability of AS03, CpG 1018 formulated in Alum, the TLR-7 agonist adsorbed to Alum (AS37), the squalene-in-water emulsion (O/W), and Alum to boost protective immunity against SARS-CoV-2.

15 Feb 2021

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

How SARS-CoV-2 enters the central nervous system

The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection?

15 Feb 2021

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

15 Feb 2021

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

15 Feb 2021

T Cell News and Research

Latest T Cell News and Research

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

Discovery opens up the possibility to predict metastases even before cancer develops

Daily caffeine consumption can change the gray matter of the brain

Top scientists, advances in analytical chemistry recognized

Raman Spectroscopy: Improving the Food Production Process

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Artemisia plant extracts show potential anti-SARS-CoV-2 activity in vitro

What are the changes in the physical phenotype of blood cells in COVID-19?

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Mink-derived SARS-CoV-2 mutations reduce antibody effectiveness

Elevated Activin A and FLRG levels correlate with worst outcomes in severe COVID-19

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

How SARS-CoV-2 enters the central nervous system

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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