Antibodies News and Research

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Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Researchers analyzed ACE2-binding inhibition and antibody binding for the SARS-CoV-2 Omicron variants in individuals with varying levels of immunity.

6 Jan 2022

Researchers create new monoclonal antibody treatment effective against both Delta and Omicron

In a new study, researchers conducted surface plasmon resonance experiments using commercially sourced SARS-CoV-2 protein reagents.

6 Jan 2022

Study suggests that previous COVID-19 infections do not affect pregnancy

A new study shows that it is exceedingly likely that past infection with SARS-CoV-2 has no significant effect on antibody or cytokine levels during pregnancy, labor or delivery.

6 Jan 2022

Researchers outline characteristics of Omicron variant immune escape and viral entry into host cells

A new study found that the Omicron variant contains a number of mutations that decrease neutralizing antibody activity and immune escape.

6 Jan 2022

Serological antibody response to SARS-CoV-2 infection at a population level

The scientists in this study used pooled convalescent serum to examine the serologic response in a population at risk of infection.

6 Jan 2022

Comparison of neutralization of SARS-CoV-2 variants of concern Omicron and Delta

The purpose of this study was to determine the breadth of neutralizing activity generated by exposure to certain SARS-CoV-2 variants, vaccinations, or both.

6 Jan 2022

Does SARS-CoV-2 Omicron variant elicited neutralizing immunity enhance that elicited by the Delta variant?

In this paper, researchers studied whether the neutralizing immunity produced by Omicron also increases neutralizing immunity of the Delta variant.

6 Jan 2022

COVID boosters hinder SARS-CoV-2 Omicron

A new preprint research paper reports on the state of current knowledge as to the immune evasion capability of this variant, linking it to the type of vaccine used and the vaccination protocol.

6 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

Researchers determine the cross-reactivity of the SARS-CoV-2 spike glycoprotein-induced antibodies before and after a third SARS-CoV-2 vaccine dose.

5 Jan 2022

Monoclonal antibody treatment of COVID-19 reduces viral shedding

Researchers aim to understand the potential benefits of mAbs in preventing and treating SARS-CoV-2 infection.

5 Jan 2022

Exploring vaccine-induced cellular immunity against SARS-CoV-2 Omicron variant

In a new study, researchers determined CD8+ and CD4+ T cell responses against the SARS-CoV-2 Omicron variant in 51 individuals vaccinated with the messenger ribonucleic acid (mRNA)-based Pfizer and adenovirus vector-based Johnson & Johnson vaccines.

5 Jan 2022

COVID-19 mRNA vaccines offer protection against Omicron variant in pregnancy

A new study provides insights into the persistence of extra-neutralizing properties of mRNA vaccine-induced antibodies resulting in protection against the Omicron variant of SARS-CoV-2.

5 Jan 2022

Oral bacteria-based SARS-CoV-2 vaccine platform

In a new study, researchers engineered the bacterial strain, Salmonella, to express differently-sized antigens to serve as vaccine platforms.

5 Jan 2022

Can the COVID-19 delta variant evade vaccine-induced immunity?

Can the COVID-19 delta variant evade vaccine-induced immunity? We spoke to Professor Brian J. Willett from the University of Glasgow to find out.

5 Jan 2022

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

A new preprint research paper posted to the medRxiv* server reports the induction of high neutralizing activity in these patients against the Omicron VOC with a booster dose.

5 Jan 2022

Scientists provide a structural framework for Omicron immune evasion and ACE2 receptor recognition

An interesting preprint research paper describes structural changes resulting from the multiple mutations found in the recent Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. In addition, the research describes the consequent effects of these changes on Omicron’s infectivity and immune evasion capabilities.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

Time since COVID vaccination is a key driver of breakthrough Omicron infections

Published on the preprint medRxiv* server and awaiting peer review, the findings showed that the significant factor behind breakthrough Omicron infections is the timing from vaccination. The time between vaccination and breakthrough infections induced effective or cross-reactive neutralizing antibodies that neutralize Omicron after Alpha or Delta breakthrough infections.

4 Jan 2022

New study on NAbs against SARS-CoV-2 Omicron variant after vaccination or infection

A recent study suggests neutralizing antibody responses against variants of concern, including Omicron, differs significantly between vaccinated and naturally infected individuals. The research, posted to the medRxiv* preprint server, focused on vaccinated individuals who are pregnant — an understudied group in COVID-19 research.

4 Jan 2022

Antibodies News and Research

Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Researchers create new monoclonal antibody treatment effective against both Delta and Omicron

Study suggests that previous COVID-19 infections do not affect pregnancy

Researchers outline characteristics of Omicron variant immune escape and viral entry into host cells

Serological antibody response to SARS-CoV-2 infection at a population level

Comparison of neutralization of SARS-CoV-2 variants of concern Omicron and Delta

Does SARS-CoV-2 Omicron variant elicited neutralizing immunity enhance that elicited by the Delta variant?

COVID boosters hinder SARS-CoV-2 Omicron

SARS-CoV-2 appears to persist in organs throughout the body for months

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

Monoclonal antibody treatment of COVID-19 reduces viral shedding

Exploring vaccine-induced cellular immunity against SARS-CoV-2 Omicron variant

COVID-19 mRNA vaccines offer protection against Omicron variant in pregnancy

Oral bacteria-based SARS-CoV-2 vaccine platform

Can the COVID-19 delta variant evade vaccine-induced immunity?

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

Scientists provide a structural framework for Omicron immune evasion and ACE2 receptor recognition

Transplant recipients benefit from a COVID-19 vaccine booster

Time since COVID vaccination is a key driver of breakthrough Omicron infections

New study on NAbs against SARS-CoV-2 Omicron variant after vaccination or infection

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