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Study highlights importance of positive and negative selection in evolution of SARS-CoV-2 variants

Researchers from the University of Colorado Anschutz Medical Campus have been investigating the changes imparted on the Gamma variant by three RBD mutations.

28 Dec 2021

SARS-CoV-2 Omicron variant neutralized by third BNT162b2 booster shot

A new preprint* research paper under consideration at Nature Portfolio Journal assesses the susceptibility of the Omicron variant to neutralizing antibody response after booster immunization.

28 Dec 2021

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

A recent study by a team of European researchers demonstrated how antibodies induced by currently circulating influenza A H1N1 strains can cross-react with the important part of the SARS-CoV-2 spike glycoprotein that interacts with the human cell receptor. Their paper is currently available on the medRxiv* preprint server while it undergoes peer review.

28 Dec 2021

Third BNT162b2 dose effectively neutralizes SARS-CoV-2 Omicron pseudovirus

The findings reveal that the Omicron neutralizing titers induced by the third vaccine dose are comparable to that achieved against the original Wuhan strain (wild-type SARS-CoV-2) by the two-dose regimen. The study is currently available on the medRxiv* preprint server while awaiting peer review.

28 Dec 2021

Study suggests spike mutation makes SARS-CoV-2 Omicron milder

The Omicron spike is relatively poorly cleaved and impaired in mediating cell-cell fusion and syncytia formation, contrary to predictions.

28 Dec 2021

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants. These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate.

28 Dec 2021

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained at high risk for hospitalization and death.

26 Dec 2021

SARS-CoV-2 Alpha variant mutated to evade the immune system

The SARS-CoV-2 Alpha (B.1.1.7) variant mutated to evade our 'innate immune system', helping establish it as the world's first 'Variant of Concern', finds a new study led by researchers at UCL and the Quantitative Biosciences Institute, University of California San Francisco.

24 Dec 2021

Study helps explain why mRNA vaccines have been successful at preventing severe COVID-19

Washington University in St. Louis student Julian McCall receives a dose of Pfizer's mRNA-based COVID-19 vaccine.

24 Dec 2021

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

A new study from Columbia researchers, in collaboration with scientists at the University of Hong Kong, adds more evidence that the omicron variant can evade the immune protection conferred by vaccines and natural infection and suggests the need for new vaccines and treatments that anticipate how the virus may soon evolve.

24 Dec 2021

Scientists identify a new Achilles' heel of influenza virus

Scientists at Scripps Research, University of Chicago and Icahn School of Medicine at Mount Sinai have identified a new Achilles' heel of influenza virus, making progress in the quest for a universal flu vaccine.

24 Dec 2021

Pfizer-BioNTech booster shot may offer better immunity than a two-dose regimen

A new study suggests that the immune response against severe acute respiratory syndrome coronavirus 2 is greater with a three-dose regimen than a two-dose regimen.

24 Dec 2021

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

New data shows that, compared to adults, children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preferentially activate pre-existing acquired immunity to prevalent common cold coronaviruses that cross-react with SARS-CoV-2 and protect them from severe disease.

24 Dec 2021

Scientists detect COVID-19 infection in white-tailed deer in 6 Ohio locations

Scientists have detected infection by at least three variants of the virus that causes COVID-19 in free-ranging white-tailed deer in six northeast Ohio locations, the research team has reported.

24 Dec 2021

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.

23 Dec 2021

Vaccinated kidney transplant recipients not adequately protected against emerging SARS-CoV-2 variants

Kidney transplant recipients tend to mount impaired antibody responses against emerging SARS-CoV-2 variants after standard two-dose COVID-19 vaccination, according to new research published in CJASN.

23 Dec 2021

Ad5-nCoV vaccine safe and effective against symptomatic, severe COVID-19, trials shows

One dose of Ad5-nCoV (Convidecia), a COVID-19 vaccine developed in China, is 57.5% effective against symptomatic COVID-19 and 91.7% effective against severe COVID-19 disease beginning 28 days postvaccination, according to a phase 3 randomized controlled trial published in The Lancet.

23 Dec 2021

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers compare the obtained binding affinities to wild-type and Delta spike proteins to determine the impact of Omicron mutations.

23 Dec 2021

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

23 Dec 2021

Children produce a much more robust antibody response to a SARS-CoV-2 infection than 18+

Scientists compared receptor binding domain antibodies and SARS-CoV-2 neutralizing antibodies in children and adults.

23 Dec 2021

Antibodies News and Research

Study highlights importance of positive and negative selection in evolution of SARS-CoV-2 variants

SARS-CoV-2 Omicron variant neutralized by third BNT162b2 booster shot

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

Third BNT162b2 dose effectively neutralizes SARS-CoV-2 Omicron pseudovirus

Study suggests spike mutation makes SARS-CoV-2 Omicron milder

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

SARS-CoV-2 Alpha variant mutated to evade the immune system

Study helps explain why mRNA vaccines have been successful at preventing severe COVID-19

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

Scientists identify a new Achilles' heel of influenza virus

Pfizer-BioNTech booster shot may offer better immunity than a two-dose regimen

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

Scientists detect COVID-19 infection in white-tailed deer in 6 Ohio locations

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

Vaccinated kidney transplant recipients not adequately protected against emerging SARS-CoV-2 variants

Ad5-nCoV vaccine safe and effective against symptomatic, severe COVID-19, trials shows

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

Children produce a much more robust antibody response to a SARS-CoV-2 infection than 18+

How to make hybridoma-based antibody discovery more efficient eBook

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Automating research - solutions and best practices

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