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Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

A recent study reveals that resveratrol, a phenolic compound produced by spermatophytes, can inhibit the viral replication SARS-CoV-2.

27 Nov 2020

Could beta-blockers be a potential treatment for COVID-19?

News-Medical spoke to researchers about their latest research into beta-blockers, and how they could potentially be used to treat COVID-19.

27 Nov 2020

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

In a preprint paper published on the medRxiv server, a team of researchers from various institutions in South Africa, the UK, and Europe discuss how they determined the impact of HIV on the COVID-19 immune response in KwaZulu-Natal, South Africa, which is an area with very high HIV prevalence.

26 Nov 2020

Transgenic mouse model could recapitulate severe COVID-19 in humans

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe disease course in humans.

26 Nov 2020

Innovative radiotherapy technique benefits patients with locally advanced cervical cancer

Patients with locally advanced cervical cancer benefit significantly from an innovative radiotherapy technique co-developed by MedUni Vienna under the direction of Richard Pötter and Christian Kirisits. The technique provides better tumor control and produces fewer side-effects.

26 Nov 2020

Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

A new multicenter study that recently appeared on the medRxiv* preprint server in November 2020 has found a lower or equal risk of fatal COVID-19 in hypertensive patients, depending on the type of medication they are on.

26 Nov 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Early use of existing treatment helps save hospitalized COVID-19 patients

The lives of patients hospitalized with COVID-19 are being saved by doctors who are using an existing medical treatment at an earlier stage.

25 Nov 2020

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Researchers in the United States have conducted a modeling study suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – could have been circulating in the Chinese province of Hubei as early as mid-October 2019.

25 Nov 2020

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

A recent study based at a hospital in Buenos Aires, Argentina, found that convalescent plasma therapy for patients with severe COVID-19, and COVID-19-related pneumonia, was largely ineffective.

25 Nov 2020

Is COVID-19 severity mediated by higher antibody response?

A new study indicates that patients with more severe COVID-19 have a stronger antibody response.

25 Nov 2020

School closures caused by COVID-19 may reduce life expectancy in U.S. children

A team that includes UCLA Fielding School of Public Health researchers has found American children whose educations have been disrupted by the pandemic, even as little as 2-4 months, may face shortened life spans.

25 Nov 2020

Scientists use demographic data to estimate test-based case fatality rates across California

A team of UCLA Fielding School of Public Health researchers has developed analyses to identify those most at risk from the pandemic, using demographic data to estimate test-based infection and test-based case fatality rates across California.

24 Nov 2020

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

Recently, researchers from the Monash University and Monash Medical Centre, Clayton, Victoria, Australia, investigated whether peptide sensitization using BCG can produce cross-reactive T cells specific to SARS-CoV-2. Their study is published on the preprint server, medRxiv.

24 Nov 2020

IU research could lead to improved breast cancer treatments for Black women

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher is identifying the unique biology that may make Black women more susceptible to aggressive breast cancer.

24 Nov 2020

Disproportionate COVID-19 mortality in England linked to non-white ethnicity and poverty

In a paper published on the preprint server medRxiv, researchers from various departments of Imperial College London, UK, discuss how they analyzed mortality data of individuals 40 years and above in local communities in England to determine local variations in increased mortality during the first wave of the pandemic – between 1 March and 31 May 2020 - and to identify the community factors associated with these mortality patterns.

24 Nov 2020

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Recently, a team of researchers studied the transmission modes of SARS-CoV-2 and the protection against re-infection in ferret models in work published on the preprint server, bioRxiv.

24 Nov 2020

Mortality News and Research

Female reproductive hormones may be protective against COVID-19

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

Could beta-blockers be a potential treatment for COVID-19?

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

Transgenic mouse model could recapitulate severe COVID-19 in humans

Innovative radiotherapy technique benefits patients with locally advanced cervical cancer

Researchers discover blood gene signatures that can predict COVID-19 severity

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

Early interferon therapy may mitigate COVID-19 severity

Early use of existing treatment helps save hospitalized COVID-19 patients

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

Is COVID-19 severity mediated by higher antibody response?

School closures caused by COVID-19 may reduce life expectancy in U.S. children

Scientists use demographic data to estimate test-based case fatality rates across California

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

IU research could lead to improved breast cancer treatments for Black women

Disproportionate COVID-19 mortality in England linked to non-white ethnicity and poverty

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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