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Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

An analysis of risk factors and symptom presentation among groups at risk for SARS-CoV-2 infection

The study, published on the pre-print server medRxiv*, analyzed the specific linkages between the COVID-19 patients belonging to the three risk groups with the overall COVID-19 patients and compared symptoms between and within the risk groups.

6 Dec 2021

COVID-19 severity is correlated with T cell receptor repertoire signatures

In a new study published in the bioRxiv* preprint server, researchers found that specific TCR sequences predicted the severity of coronavirus disease 2019 (COVID-19) infection. Additionally, there was evidence of increased CDR3 sequences and changes in k-mer motifs for patients with severe illness.

6 Dec 2021

Simple quantitative framework to understand the pathogenesis of severe COVID-19

Researchers from Los Alamos National Laboratory in the United States developed a model to explain why severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections induce high inflammatory levels.

6 Dec 2021

Omicron variant increases risk of SARS-CoV-2 reinfection

New surveillance data from South Africa published in the medRxiv* preprint server suggests that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omnicron variant has the potential to escape naturally-acquired immunity. The research indicates people who previously recovered from a coronavirus disease 2019 (COVID-19) are at risk for reinfection with the Omicron variant. The results show that the risk of reinfection is greater with the Omicron variant versus Delta and Beta.

6 Dec 2021

Disparities in maternal mental health during COVID-19

In new research, scientists studied individuals who gave birth during COVID-19. Using propensity score matching (PSM), they matched those identified as either Black or Latinx with those identified as non-Hispanic white on sociodemographic. This recent study published as a preprint on the medRxiv* server attempts to assess the impact of the COVID-19 pandemic on childbirth-related health outcomes in individuals belonging to Black or Latinx minority groups.

6 Dec 2021