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Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

Unique antibody responses after third COVID-19 mRNA vaccination

Researchers observed that a third messenger ribonucleic acid COVID-19 vaccine elicits a unique antibody response.

16 May 2022

Early impact of SARS-CoV-2 on human lungs

In a new study, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on human lung cells.

16 May 2022

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

Researchers observed that the SARS-CoV-2 Omicron BA.2 variant is immunologically different from other variants, including Omicron BA.1.

16 May 2022

Super-antibody UT28K shows broad-spectrum activity against SARS-CoV-2 variants

A study, published online in the journal mAbs, describes a novel mAb, UT28K, that has promising broadly neutralizing activity against the SARS-CoV-2 virus.

15 May 2022

Scientists examine the impact of herpesviruses on (pre)diabetes

Scientists have recently analyzed the association between herpesviruses and type 2 diabetes. This study is available in the journal Diabetologia.

15 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Creating the industry’s first stem cell analysis update in nearly 25 years, Beckman Coulter Life Sciences – a global leader in laboratory automation and innovation – launches an evolution of the gold standard in hematopoietic stem cell enumeration, the AQUIOS STEM System.

13 May 2022

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

A team of scientists has recently studied the kinetic and thermodynamic characteristics of interaction between human ACE2 and spike receptor-binding domains of different variants of SARS-CoV-2.

13 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

Cost-effective ovine antibody-based therapy against SARS-CoV-2 infection

A recent study published in the journal Antiviral Research explored alternative sources of polyclonal antibodies against SARS-CoV-2, which would be more cost-effective, amendable to regulatory approval, and widespread use.

12 May 2022

T-cell responses after COVID-19 and vaccinations

A new study published in the journal Frontiers in immunology examines the cell-mediated immunity in BNT162b2 COVID-19 mRNA vaccinated health care workers and COVID-19 patients.

12 May 2022

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

A new study has focussed on determining the clonality and levels of SARS-CoV-2-reactive CD4+ T cells in CCPs post-vaccination.

12 May 2022

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Researchers performed an unbiased evaluation of the early memory B cell repertoire specific for the Omicron and Delta variants of SARS-CoV-2.

12 May 2022

Study shows reduced respiratory syncytial virus antibody levels in women of childbearing age and infants during the COVID-19 pandemic

A study demonstrated that the humoral immunity against the respiratory syncytial virus (RSV) has significantly reduced.

12 May 2022

Messenger RNA COVID-19 vaccines induce high levels of short-lived antibodies compared to natural infection

Researchers extensively investigated the dynamics of antibodies induced by natural SARS-CoV-2 infection and vaccination in Qatar's diverse population

12 May 2022

SARS-CoV-2 Omicron escapes immune response due to high ACE2 affinity and low antibody specificity

In a recent study published in the journal Vaccines, researchers revealed how severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron evades neutralizing antibodies (nAbs).

12 May 2022

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

Study investigates antibody-mediated response against different SARS-CoV-2 variants

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on antibody-mediated immunity.

10 May 2022

Assay News and Research

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

Unique antibody responses after third COVID-19 mRNA vaccination

Early impact of SARS-CoV-2 on human lungs

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

Super-antibody UT28K shows broad-spectrum activity against SARS-CoV-2 variants

Scientists examine the impact of herpesviruses on (pre)diabetes

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

Cost-effective ovine antibody-based therapy against SARS-CoV-2 infection

T-cell responses after COVID-19 and vaccinations

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Study shows reduced respiratory syncytial virus antibody levels in women of childbearing age and infants during the COVID-19 pandemic

Messenger RNA COVID-19 vaccines induce high levels of short-lived antibodies compared to natural infection

SARS-CoV-2 Omicron escapes immune response due to high ACE2 affinity and low antibody specificity

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

Discovery of host co-factors necessary for SARS-CoV2 infection

Study investigates antibody-mediated response against different SARS-CoV-2 variants

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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