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Supercomputer helps find 64 compounds as potential inhibitors of the COVID-19 protease

A new study published in Chemrxiv in April 2020 describes the identification of 64 compounds that could potentially be inhibitors of replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the current COVID-19 disease pandemic. The research was carried out using a pharmacophore model of an essential viral enzyme, mining data from the Food and Drug Administration (FDA) database of conformations of approved drugs.

16 Apr 2020

Six novel coronaviruses found in bats

While the world grapples with the pandemic, which has spread to 185 countries and territories, infecting more than 2.15 million people and killing more than 143,000 people, a team of researchers at the Smithsonian's Global Health Program has found six novel coronaviruses in bats in Myanmar.

16 Apr 2020

Research shows speed of asymptomatic SARS-CoV-2 transmission in Boston homeless shelter

The coronavirus disease (COVID-19) is straining healthcare resources across the globe, prompting countries to impose social distancing measures to reduce the transmission of the virus. The problem is, the virus can spread even if the infected person has no symptoms, making contact tracing and isolation measures more difficult. Now, a new study reveals the rapidity of asymptomatic SARS-CoV-2 transmission that occurred in a Boston homeless shelter.

16 Apr 2020

Are overactive immune cells causing COVID-19-related deaths?

While the COVID-19 pandemic is devastating many regions, the world over, a new paper published in the Journal of Experimental Medicine in April 2020 describes the possibility that the critical or very severe cases of COVID-19 are due to the production of neutrophil extracellular traps (NET) due to hyperactivated immune cells.

16 Apr 2020

Pregnancy and fetal outcomes with COVID-19

A new study published preprint in the non-peer-reviewed journal medRxiv in April 2020 provides a systematic review of maternal and fetal outcomes in pregnancy affected by COVID-19, as well as the risk of vertical transmission of the virus.

16 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Mental health may be significantly impacted by COVID-19-related social distancing and isolation

A study conducted by a team of psychologists and social scientists has revealed that the social distancing and isolation measures introduced in the UK as a result of COVID-19 may already be having significant negative impacts on people's mental health and well-being.

16 Apr 2020

Interactive tool helps identify potential shortages of COVID-19 workforce

As the U.S. healthcare workforce struggles to care for a rise in COVID-19 cases, there are growing reports that there are not enough workers to meet the surge in demand.

16 Apr 2020

New antiviral drug reduces transmission of influenza, study shows

The antiviral drug, baloxavir (tradename Xofluza), is the first treatment for influenza with a new mode of "action" to be licensed in nearly 20 years.

16 Apr 2020

Scripps Research establishes collaborative global effort to rapidly find drugs against COVID-19

With the COVID-19 pandemic continuing to spread across the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

16 Apr 2020

Potential universal Ebola vaccine may neutralize all four harmful virus species

Infectious disease scientists report early development of a potential universal vaccine for Ebola viruses that preclinical tests show might neutralize all four species of these deadly viruses infecting people in recent outbreaks, mainly in Africa.

16 Apr 2020

Researchers design peptide inhibitors for potential COVID-19 treatments

Scientists across the globe are rushing to find inhibitors of SARS-CoV-2, the new coronavirus behind the COVID-19 pandemic.

16 Apr 2020

Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

Big brother wants to track your location and health data. And that’s not all bad.

A growing mix of health and technology experts are convinced that if the United States is to ever effectively track the coronavirus and slow its spread, then both self-reported and more surreptitiously gathered personal data — a mix of information about location, travel, symptoms and health conditions - must be gathered from millions of Americans.

16 Apr 2020

Trial to evaluate how blood pressure medications affect outcomes among COVID-19 patients

A new trial led by the Perelman School of Medicine at the University of Pennsylvania will evaluate whether the use of medications to treat high blood pressure affect outcomes among patients who are prescribed the medication and hospitalized with COVID-19.

16 Apr 2020

Caring for geriatric patients during COVID-19 pandemic requires vigilance

As the coronavirus disease (COVID-19) pandemic advances so does the uncertainty and evolution of the pandemic as it relates to nursing homes and long-term care facilities

16 Apr 2020

WHO-recommended hand rub formulations effective against novel coronavirus

When used correctly, both alcohol-based hand disinfectants recommended by the World Health Organization (WHO) are effective against the novel coronavirus Sars-Cov-2, as confirmed by an international research team headed by Professor Stephanie Pfänder from the Department of Molecular and Medical Virology at Ruhr-Universität Bochum.

16 Apr 2020

Octapharma USA supports new COVID-19 clinical trial

Octapharma USA is supporting a new investigator initiated clinical trial led by George Sakoulas, M.D. of Sharp Memorial Hospital in San Diego, California focused on treating the most critical patients at the heart of the coronavirus pandemic, those experiencing respiratory failure who become ventilator dependent.

16 Apr 2020

Public health precautions to lower airborne transmission of COVID-19 virus

Researchers are urging health authorities to immediately recognize the role of airborne transmission of COVID-19 virus droplets from an infected person beyond 1.5m in order to stem the disease’s spread.

16 Apr 2020

Blood test may help doctors catch pancreatic cancer early

A blood test may be able to detect the most common form of pancreatic cancer while it is still in its early stages.

16 Apr 2020

Disease/Infection News

Supercomputer helps find 64 compounds as potential inhibitors of the COVID-19 protease

Six novel coronaviruses found in bats

Research shows speed of asymptomatic SARS-CoV-2 transmission in Boston homeless shelter

Are overactive immune cells causing COVID-19-related deaths?

Pregnancy and fetal outcomes with COVID-19

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

Mental health may be significantly impacted by COVID-19-related social distancing and isolation

Interactive tool helps identify potential shortages of COVID-19 workforce

New antiviral drug reduces transmission of influenza, study shows

Scripps Research establishes collaborative global effort to rapidly find drugs against COVID-19

Potential universal Ebola vaccine may neutralize all four harmful virus species

Researchers design peptide inhibitors for potential COVID-19 treatments

Specialized proteins could soak up excess cytokines in COVID-19 patients

Big brother wants to track your location and health data. And that’s not all bad.

Trial to evaluate how blood pressure medications affect outcomes among COVID-19 patients

Caring for geriatric patients during COVID-19 pandemic requires vigilance

WHO-recommended hand rub formulations effective against novel coronavirus

Octapharma USA supports new COVID-19 clinical trial

Public health precautions to lower airborne transmission of COVID-19 virus

Blood test may help doctors catch pancreatic cancer early

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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