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Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

Science-based technology company 3M has awarded a significant philanthropic research grant of $400,000 to the Shmunis School of Biomedicine and Cancer Research at Tel Aviv University to advance scientific knowledge in the global response to the COVID-19 pandemic.

8 Sep 2020

The T cell responses in COVID-19 recovered individuals

A recent study demonstrates that functional CD4+ and CD8+ T cells specifically targeting the entire proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain active in individuals who have recovered from severe or mild coronavirus disease 2019 (COVID-19). Moreover, the magnitude of T cell response is correlated with the antibody response. The study is published in the journal Nature Immunology.

8 Sep 2020

Racial disparities could be the key reason for COVID-19 mortality among Black essential workers

Racial disparities among essential workers could be a key reason that Black Americans are more likely than whites to contract and die of COVID-19, according to researchers at the University of Utah.

8 Sep 2020

Study suggests a wider distribution range of Ebola virus carriers in Africa than previously assumed

Zaire ebolavirus is among the deadliest of all known Ebola viruses for humans and is most likely transmitted by various species of bats.

8 Sep 2020

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Patients hospitalized with severe COVID-19 infections who have high levels of the blood clotting protein factor V are at elevated risk for serious injury from blood clots such as deep vein thrombosis or pulmonary embolism, investigators at Massachusetts General Hospital (MGH) have found.

8 Sep 2020

Card-based system to track asymptomatic individuals helps reduce COVID-19 spread

The COVID-19 pandemic has had an adverse impact on the global economy. Researchers around the globe have been working hard to find ways to stop the spread of the disease either in the form of drugs or SOP changes that revolve around guidelines given by the WHO for maintaining hygiene and social distancing norms.

8 Sep 2020

Countries should step-up leprosy prevention initiatives to accelerate decline in new cases

New cases of leprosy are decreasing, but not at the anticipated rate. In order to accelerate the annual decline, countries should screen contacts and treat eligible contacts with single-dose rifampicin, as recommended by the World Health Organization in its guidelines.

8 Sep 2020

Study addresses the role of macrophage activation syndrome in COVID-19

Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.

8 Sep 2020

Research suggests school reopenings contribute to rise in COVID-19 cases

A study recently published on the preprint server medRxiv in September 2020 by researcher Richard Beesley at Juvenile Arthritis Research reports on the impact of school reopenings on the spread of the virus.

8 Sep 2020

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Eye research charity Fight for Sight is partnering with Diabetes UK to investigate if people with the eye disease diabetic retinopathy are at greater risk of developing complications from Covid-19, in a study that hopes to save lives.

8 Sep 2020

Limited gut inflammation in COVID-19

A new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in September 2020 shows that gut infection with this virus produces primarily mucosal immunity but also a limited inflammatory response.

8 Sep 2020

Study finds strong T cell responses in patients recovered from COVID-19

Oxford University researchers have found that natural infection with COVID-19 produces a robust T cell response, including inducing T cell ‘memory’ to potentially fight future infections.

8 Sep 2020

Antibody-mediated platelet death linked to COVID-19 severity

A new study by University of Tuebingen researchers shows the strong association between platelet apoptosis and the thrombotic manifestations that may underlie critical COVID-19 illness.

7 Sep 2020

Scientists describe various dynamic structures of the SARS-CoV-2 spike protein

Early in the pandemic, scientists uncovered the role of the ACE2 receptor in SARS-CoV-2, the virus that causes the coronavirus disease (COVID-19). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and the angiotensin-converting enzyme 2 (ACE2) receptors act as a lock and key for cell infection.

7 Sep 2020

PI3K/mTOR and topoisomerase inhibitors suggested as candidates to reduce expression of ACE2

A recent study published in the preprint server medRxiv in September 2020 shows that the already approved drug families called P13K/mTOR and topoisomerase inhibitors may be useful in reducing individual susceptibility to the virus.

7 Sep 2020

SARS-CoV-2 containment and elimination strategy will require long-term population-wide prevention measures

By introducing a model that reveals long SARS-CoV-2 transmission chains and inadequate passive surveillance systems, a new medRxiv* preprint paper shows that bringing the infection completely under control will have to rely on presumptive, stringent, longer and more burdensome population-wide prevention measures already employed against community transmission.

7 Sep 2020

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

7 Sep 2020

Disease/Infection News

Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

The T cell responses in COVID-19 recovered individuals

Racial disparities could be the key reason for COVID-19 mortality among Black essential workers

Study suggests a wider distribution range of Ebola virus carriers in Africa than previously assumed

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Card-based system to track asymptomatic individuals helps reduce COVID-19 spread

Countries should step-up leprosy prevention initiatives to accelerate decline in new cases

Study addresses the role of macrophage activation syndrome in COVID-19

Research suggests school reopenings contribute to rise in COVID-19 cases

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Limited gut inflammation in COVID-19

Study finds strong T cell responses in patients recovered from COVID-19

Antibody-mediated platelet death linked to COVID-19 severity

Scientists describe various dynamic structures of the SARS-CoV-2 spike protein

PI3K/mTOR and topoisomerase inhibitors suggested as candidates to reduce expression of ACE2

SARS-CoV-2 containment and elimination strategy will require long-term population-wide prevention measures

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Three-year Indonesia trial produces encouraging results for dengue control

Important research on SARS-CoV-2 proteins using proximity labeling

COVID-19 caused substantial disruptions to essential health services in most countries

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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