Molecular & Structural Biology

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Novel genetic mapping study traces links between DNA variations and blood proteins

A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct populations. The results should help researchers better understand the molecular causes of diseases and identify proteins that could be targeted to treat these diseases.

3 May 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and integrate the signals from outside with endogenous developmental programs.

28 Apr 2022

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Researchers at Ural Federal University have proposed the use of polyoxometallate nanoclusters as a carrier for chemotherapy drug. It will help to deliver medications precisely to the focus of a pathological process, such as a cancerous tumor, without toxic effects on healthy cells.

28 Apr 2022

Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Researchers revealed that native FokI relaxation might be induced, resulting in FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids.

27 Apr 2022

Molecular & Structural Biology

Novel genetic mapping study traces links between DNA variations and blood proteins

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Genetic cause of lupus identified

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

UNIGE scientists develop a novel tool to visualize palmitoylation process in living cells

Salk scientists identify a protein that is critical for preventing pancreatic auto-digestion in mice

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

New research takes a close look at the most prevalent neurotransmitter in the brain

CryoEM reveals never-before-seen details of the human androgen receptor

Scientists demonstrate a new mechanism by which amino acids curb appetite

New deep learning neural network model predicts physical interactions of protein complexes

Using customized 'mini-antibodies' to mitigate chronic inflammation

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

SARS-CoV-2 infection patterns in olfactory epithelium

SARS-CoV-2 RBD is a selective integrin agonist

Role of cGAS-STING in SARS-CoV-2 infection

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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