Molecular & Structural Biology

RSS

Chromosome organization affects evolution of DNA in archaea

The structure of how DNA is stored in archaea makes a significant difference to how quickly it evolves, according to a new study by Indiana University researchers.

14 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Of the three groups of rotavirus that cause gastroenteritis in people, called groups A, B and C, groups A and C affect mostly children and are the best characterized.

9 Jun 2022

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

From Curia 9 Jun 2022

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Scientists have, for the first time, revealed at the atomic level the structure of a protein that carries one of the body's most important neurotransmitters into neurons.

8 Jun 2022

Diet rich in polyphenols can prevent inflammation in the elderly

Polyphenols in the foods that we eat can prevent inflammation in older people, since they alter the intestinal microbiota and induce the production of the indole 3-propionic acid (IPA), a metabolite derived from the degradation of tryptophan due to intestinal bacteria.

8 Jun 2022

Where did Omicron's unique spike gene insertion originate?

In a recent study posted to the medRxiv* pre-print server, scientists at nference Labs investigated the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron's unique spike (S) gene insertion ins214EPE.

8 Jun 2022

Basolateral amygdala may play a larger, overarching role during naturalistic events

The basolateral amygdala (BLA) is a region of the brain that has been almost exclusively studied in the context of fear and emotion.

7 Jun 2022

MIT researchers identify components of mucus that can inhibit fungal infections

Candida albicans is a yeast that often lives in the human digestive tract and mouth, as well as urinary and reproductive organs.

6 Jun 2022

Persistence of viral RNA following acute infection

Professor Diane Griffin from the Johns Hopkins Bloomberg School of Public Health, USA, has recently explained the persistence mechanism of viral RNA in the human body after clinical recovery from acute infection.

6 Jun 2022

Using DNA droplets for early disease detection

Aqueous droplet formation by liquid-liquid phase separation (or coacervation) in macromolecules is a hot topic in life sciences research.

3 Jun 2022

Scientists propose a neurocomputational model of creative processes

"Many believe that creativity is assigned to a single brain region. But that is not the case," said Radwa Khalil. Together with scientists from South Africa and Australia, the neurobiologist at Jacobs University Bremen has proposed a computer-based model that assigns creative processes to neural networks in the brain.

3 Jun 2022

Neuroscientists study the formation of fear memories in the brain's emotional hub

Experiencing a frightening event is likely something you'll never forget. But why does it stay with you when other kinds of occurrences become increasingly difficult to recall with the passage of time?

1 Jun 2022

Interactive web portal details the extent of splicing events in noncoding sequences

An online tool reveals the extent of gene-restructuring events in noncoding sequences.

30 May 2022

EEG data reveals when and where odors are processed in the brain

A specially created odor delivery device, along with machine learning-based analysis of scalp-recorded electroencephalogram, has enabled researchers at the University of Tokyo to see when and where odors are processed in the brain.

29 May 2022

Specific neural circuit in mice can help detect the dimmest shadows possible

Mice use a specific neural pathway to detect shadows, and it can detect just about the dimmest shadows possible, according to new research from Aalto University and the University of Helsinki. The human eye has the same neural circuit, which researchers think could be used to probe visual diseases at unprecedented resolution.

26 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

A sugar-studded protein could be key to stopping Alzheimer’s disease progression, finds study

In a bit of "reverse engineering" research using brain tissues from five people who died with Alzheimer's disease, Johns Hopkins Medicine researchers say they discovered that a special sugar molecule could play a key role in the development of Alzheimer's disease.

25 May 2022

Molecular & Structural Biology

Chromosome organization affects evolution of DNA in archaea

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Deciphering the structure of nuclear pore complex piece by piece

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Diet rich in polyphenols can prevent inflammation in the elderly

Where did Omicron's unique spike gene insertion originate?

Basolateral amygdala may play a larger, overarching role during naturalistic events

MIT researchers identify components of mucus that can inhibit fungal infections

Persistence of viral RNA following acute infection

Using DNA droplets for early disease detection

Scientists propose a neurocomputational model of creative processes

Neuroscientists study the formation of fear memories in the brain's emotional hub

Interactive web portal details the extent of splicing events in noncoding sequences

EEG data reveals when and where odors are processed in the brain

Specific neural circuit in mice can help detect the dimmest shadows possible

The role of pyroptosis in COVID-19

A sugar-studded protein could be key to stopping Alzheimer’s disease progression, finds study

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Latest Life Science News