Molecular & Structural Biology

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Scientists identify a new protein that turbocharges gene expression

For many years, scientists have sought to understand what happens when our genes are flipped to the "on" position. Now, scientists at the University of California San Diego and Rutgers University have identified a new protein that contributes to this important process.

11 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Research sheds light on important events that may play a role in infertility

Everyone considers sperm to be made exclusively by males. But did you know that females also make sperm? Well, it turns out that females also contribute to what makes a sperm a sperm.

8 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Researchers from Columbia Engineering, Fiocruz's Center for Technological Development in Health and the Oswaldo Cruz Institute in Brazil, Memorial Sloan Kettering Cancer Center, and Rockefeller University recently reported that, by combining inhibitors of polymerases and exonucleases--enzymes that allow SARS-CoV-2 to reproduce--they were able to reduce SARS-CoV-2 replication 10 times more than when using just the polymerase inhibitors.

7 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Study provides new insights into the communication of bacteria with their host

A newly discovered protein helps bacteria recognize stress hormones in the human body and direct their motion in the host.

7 Mar 2022

Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

Biologists from ETH Zurich have discovered speargun-like molecular injection systems in two types of bacteria and have described their structure for the first time.

7 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Researchers discover a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Sugar-decorated proteins in mucus could prevent SARS-CoV-2 viruses from spreading from surfaces

Early in the pandemic, many people fastidiously disinfected surfaces because laboratory studies predicted that SARS-CoV-2 could be easily transmitted in this way.

2 Mar 2022

Australian bull ants' venom component exploits a pain pathway in mammals

Australian bull ants have evolved a venom molecule perfectly tuned to target one of their predators – the echidna – that also could have implications for people with long-term pain, University of Queensland researchers say.

2 Mar 2022

Intestinal cells can change specializations during their lives, finds study

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

1 Mar 2022

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Research sheds light on the role of lipids in Alzheimer’s disease development

Neurons in the brain coexist with and rely on many other cell types to function properly. Astrocytes, which take their name from their star shape, ensure the survival of neurons by feeding and detoxifying them with the help of a multifunctional protein, APOE.

1 Mar 2022

Researchers demonstrate the powerful gene silencing effects of HDO technology

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

28 Feb 2022

Molecular & Structural Biology

Scientists identify a new protein that turbocharges gene expression

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

The trajectory of B-cell immunity six months after mRNA vaccination

CRIPSR identifies cell-type-specific ACE2 modifiers

Research sheds light on important events that may play a role in infertility

How will mutations change the SARS-CoV-2 spike protein in the future?

A promising approach for COVID-19 prophylaxis

Study offers insight into molecular biology of the brain in bipolar disorder patients

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

NETosis in COVID-19 and MIS-C

Study provides new insights into the communication of bacteria with their host

Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

CD4 T-cell immunity active six months into COVID-19 convalescence

Researchers discover a nuclear import mechanism essential for organ growth and development

Sugar-decorated proteins in mucus could prevent SARS-CoV-2 viruses from spreading from surfaces

Australian bull ants' venom component exploits a pain pathway in mammals

Intestinal cells can change specializations during their lives, finds study

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

Research sheds light on the role of lipids in Alzheimer’s disease development

Researchers demonstrate the powerful gene silencing effects of HDO technology

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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