Molecular & Structural Biology

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New research shines light on mysterious dynamics that define the interplay between nerves and muscle

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Researchers discover a novel group of proteins that exists in all domains of life

Proteins are the "workhorses" in every living cell and constitute the chemical basis of life. These little machines are required to turn food into energy, to manage motion and brain activities and to fight off bacteria and viruses.

17 Feb 2022

Researchers discover a new and unconventional nuclear function for cancer microRNA

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Zebrafish model reveals how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Precise communication of two key memory regions boosts formation of lasting memories

In a new, rare study of direct brain recordings in children and adolescents, a Northwestern Medicine scientist and colleagues from Wayne State University have discovered as brains mature, the precise ways by which two key memory regions in the brain communicate make us better at forming lasting memories.

15 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers identify and investigate the presence and evolution of the SARS-CoV-2 N and S glycoprotein proteins.

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases.

14 Feb 2022

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

14 Feb 2022

Physicists investigate the usefulness of gene expression tests for cancer therapy

Following surgery, patients with breast cancer are faced with the question of whether additional chemotherapy is necessary and really effective.

14 Feb 2022

Molecular cage helps researchers to get atomic-level details of key cancer protein

Acute myeloid leukemia (AML), the American Cancer Institute estimates, will affect more than 20,000 Americans this year and kill more than 11,000 of them.

11 Feb 2022

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to research published today in PLOS Genetics.

11 Feb 2022

Research reveals key role of p53 protein in epithelial migration and tissue repair

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair.

11 Feb 2022

Novel molecule shows ability to inhibit the replication of all coronaviruses

Uppsala researchers have succeeded in designing a molecule that inhibits the replication of coronaviruses and that has great potential for development into a drug suitable for treating COVID-19.

10 Feb 2022

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome.

9 Feb 2022

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

Researchers describe the impact of changes in the Omicron variant on a uniquely immunodominant spike-encoded CD8+ T-cell epitope.

9 Feb 2022

Researchers discover a molecular indicator and regulator of social isolation in female mice

As we have experienced during the COVID pandemic, loneliness, or perceived social isolation, is a major stress for social animals and increases the risk of various mental and physical health issues such as depression, substance abuse, obesity, and premature death.

9 Feb 2022

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Drugs which are commonly-used as the first line of treatment for colorectal cancer cause the tumor cells to oversecrete proteins known as mucins, according to a new study published today in the journal eLife.

9 Feb 2022

Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

Molecular & Structural Biology

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

Researchers discover a novel group of proteins that exists in all domains of life

Researchers discover a new and unconventional nuclear function for cancer microRNA

Zebrafish model reveals how early embryo cells begin to independently produce proteins

Precise communication of two key memory regions boosts formation of lasting memories

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Prediction of SARS-CoV-2 epitope candidates for future vaccines

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Physicists investigate the usefulness of gene expression tests for cancer therapy

Molecular cage helps researchers to get atomic-level details of key cancer protein

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

Research reveals key role of p53 protein in epithelial migration and tissue repair

Novel molecule shows ability to inhibit the replication of all coronaviruses

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

Researchers discover a molecular indicator and regulator of social isolation in female mice

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Defective mitochondrial DNA could be modified using gene-editing techniques

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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