T Cell News and Research

Latest T Cell News and Research

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

Scientific advances in cancer research and new means of diagnosis and treatment have made it possible to cure many patients.

26 Apr 2021

AI platform can identify specific proteins that allow bacteria to infect the intestines

Researchers from Tel Aviv University have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines - a method that paves the way for the creation of smart drugs that will neutralize the proteins and prevent disease, without the use of antibiotics.

26 Apr 2021

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

However, with the waning of the immune response, it is not clear if these older people respond to the vaccine as well as younger individuals do. A recent study explored this question and found that though the antibody levels were somewhat lower in this group, they were still robust. This is a promising observation.

26 Apr 2021

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

A new study deals with the inhibitory activity of a membrane protein that has broad-spectrum activity against multiple viruses, showing that this is due to its effect on cytoplasmic lysine residue incorporation into replicating virions.

26 Apr 2021

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

A new study deals with the screening of the Drug Repurposing Hub (DRH) library for identifying small compounds which are capable of inhibiting SARS-CoV-2 using both in vitro and in vivo experimental studies. These molecules could be used for designing a novel therapeutic system against SARS-CoV-2 infection.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

SARS-CoV-2 limits type I and type III IFN protein biogenesis

New research led by Roy Parker of the University of Colorado Boulder finds that SARS-CoV-2 prevents the IFN response despite an increased presence of IFN-encoding mRNAs by suppressing transcriptional processes. Inhibition of IFN mRNAs triggers degradation from the activation of RNase L and the SARS-CoV-2 protein Nsp1.

26 Apr 2021

Recombinant protein vaccine fails expectations for SARS-CoV-2 neutralization

New interim results of a phase 1-2 clinical trial published in The Lancet Infectious Diseases tested the safety and effectiveness of an adjuvanted recombinant protein vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) called CoV2 preS dTM.

26 Apr 2021

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected.

26 Apr 2021

Potential new COVID vaccine from Australia

Phase 1 trial results published in The Lancet Infectious Diseases found a new subunit vaccine —an MF59-adjuvanted subunit vaccine using recombinant spike glycoprotein stabilized in a prefusion conformation by a novel molecular clamp — targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was safe and effective in producing an antigen-specific response in healthy adults.

26 Apr 2021

Study to evaluate how people with immune system deficiencies respond to COVID-19 vaccination

A study assessing how people with immune system deficiencies or dysregulations respond to COVID-19 vaccination has begun enrolling participants at the National Institutes of Health Clinical Center in Bethesda, Maryland.

26 Apr 2021

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

A new multidisciplinary study from Australia, published in the open-access journal mBio, shows that three compounds used to treat cystic fibrosis, dry eye, and a specific medical dye may lead to future strategies for the treatment of coronavirus disease (COVID-19).

25 Apr 2021

Single dose of Pfizer-BioNTech COVID-19 vaccine induces immunity in CML patients

Researchers in the UK have shown that a single dose of the Pfizer-BioNTech vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced antibody and cellular responses in patients with chronic myeloid leukemia (CML) who were taking tyrosine kinase inhibitors.

25 Apr 2021

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

There are many different types of cancer, but they all have one thing in common: errors in the signals that control normal cell behavior can cause uncontrolled cell growth and cell division, leading to a tumor.

23 Apr 2021

Researchers develop computer model to predict the impact of individual receptors on brain activity

Researchers regard the overall distribution of receptors in the brain – the receptome – as a new approach for computer models that reproduce the function of the brain, and for diagnostics and therapy of mental disorders.

23 Apr 2021

New platform helps non-experts use AI to analyze microscopy images

A new, freely available platform helps non-experts use artificial intelligence to analyze microscopy images. The platform has been developed at Åbo Akademi University in Finland and Instituto Gulbenkian de Ciência, Portugal, and will be of big help in research and diagnostics using modern day microscopes.

23 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Recreating early embryos using stem cells

In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos.

23 Apr 2021

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

The first National Institutes of Health National Cancer Institute-funded clinical study examining stereotactic body radiotherapy (SBRT) in the treatment of oligometastatic breast, prostate, and non-small cell lung (NSCLC) cancers displayed evidence that SBRT can be safely used to treat patients who have multiple metastases.

23 Apr 2021

New imaging technique captures movies of receptors on the surface of living cells

A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children's Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.

23 Apr 2021

T Cell News and Research

Latest T Cell News and Research

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

AI platform can identify specific proteins that allow bacteria to infect the intestines

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

Researchers investigate how oxygen radicals protect against cancer

SARS-CoV-2 limits type I and type III IFN protein biogenesis

Recombinant protein vaccine fails expectations for SARS-CoV-2 neutralization

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Potential new COVID vaccine from Australia

Study to evaluate how people with immune system deficiencies respond to COVID-19 vaccination

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

Single dose of Pfizer-BioNTech COVID-19 vaccine induces immunity in CML patients

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

Researchers develop computer model to predict the impact of individual receptors on brain activity

New platform helps non-experts use AI to analyze microscopy images

Researchers create a cell library to study how various sugars bind to and interact with receptors

Recreating early embryos using stem cells

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

New imaging technique captures movies of receptors on the surface of living cells

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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