Influence of Magnesium Stearate on the Electrical Charge of Lactose

Image Credit: Granutools

Granular materials and fine powders are used across various industrial processes and applications. To optimize and control processing methods, these materials have to be characterized precisely.

Certain characterization methods are related either to the properties of the grains (morphology, granulometry, chemical composition) and to the behavior of the bulk powder (blend stability, flowability, density, electrostatic properties).

However, concerning the physical behavior of bulk powder, most of the methodologies used in R&D or quality control laboratories still rely on old measurement techniques.

During the last decade, these techniques have been modified to meet the present requirements of production departments and R&D laboratories. Particularly, the measurement processes have been automatized and meticulous initialization processes have been established to obtain reproducible and interpretable results.

Moreover, new image analysis techniques vastly improve the precision of measurements.

A broad range of measurement methods have been developed to cover all the requirements of the industries processing powders and granular materials.

However, in this article only the GranuCharge instrument will be presented.

GranuCharge

Electrostatic charges are generated inside a powder during a flow. This appearance of electric charges is due to the triboelectric effect, which is an exchange of charges at the contact between two solids.

During the flow of a powder inside a device (silo, mixer, conveyor), the triboelectric effect occurs at the contact point between the grains as well as at the contact between the grains and the device itself.

Therefore, the characteristics of the powder and the composition of the material used to build the device are crucial parameters.

The GranuCharge instrument automatically precisely measures the quantity of electrostatic charges generated inside a powder during a flow whilst in contact with a selected material. The flow of the powder sample inside a vibrating V-tube falls into a Faraday cup connected to an electrometer. The electrometer measures the charge the powder obtains during the flow inside the V-tube.

In order to acquire repeatable and reproducible results, a vibrating or rotating device is used to regularly feed the V-tube.

Selected Powders

One lactose powder was selected: InhaLac 400.
This product was provided by Meggle Pharma®

InhaLac is crystalline lactose powder of high quality, designed for DPIs (Dry Powders Inhalers).

Image Credit: Granutools

Granutools decided to study the influence of an anti-static agent in this article: Magnesium Stearate. Five different blends with a different Magnesium Stearate mass fraction: 0, 1, 3, 4 and 5% were taken into consideration.

GranuCharge Analysis

Experimental Protocol

The triboelectric effect of the powders was examined with the assistance of the GranuCharge device.

During each experiment with the GranuCharge, Stainless-Steel 316L pipes and a vibrating feeder were used:

Image Credit: Granutools

The amount of powder used for each measurement was 20-30 g and the powder was discarded immediately after measurement. All powders were analyzed under standard conditions (43.0%RH and 21.2 °C).

At the start of the test, the initial powder charge density (qi, in nC/g) is recorded by introducing powder inside the Faraday cup.

Once completion of this step is achieved, the powder is then poured inside the rotating feeder, and then the experiment is fully initiated.

The final charge density is taken at the end of experiment (qf, nC/g).

Table 1 summarizes all results acquired using the GranuCharge instrument.
The charge density variation correlates to the variance between the final charge (qf) and the initial charge (q0) densities (∆q=q_f- q_0, in nC/g):

Image Credit: Granutools

The subsequent chart is representative of the charge density variation versus the Magnesium Stearate mass fraction (in %). A straight line is observable just to guide the eye:

Image Credit: Granutools

Results Interpretation

Figure 2 is particularly interesting because this illustration highlights the influence of the inclusion of Magnesium Stearate has on the electrical charge acquired by InhaLac 400 after a flow in direct contact with Stainless-Steel 316L pipes.

As evidenced, when only the Inhalac 400 product is used, the powder is highly sensitive to electrical charges (∆q = -4.6 nC/g).

However, when the Magnesium Stearate amount increases by mass fraction we can see a decrease in the charge density variation.

Furthermore, a Magnesium Stearate mass fraction close to 3% reaches a plateau (charge density variation close to -0.750 nC/g).

Conclusions

The influence the  Magnesium Stearate addition has on the electrical charge of an Inhalac 400 product can be highlighted in a straightforward manner with the GranuCharge instrument.

With only 3% of Magnesium Stearate, electrostatic charges are limited after a flow in contact with Stainless-Steel 316 pipes.

Therefore, this instrument is decidedly sensitive, accurate (average error close to 7.8%) and it can quantify the product formulation.

Bibliography

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  • Combined effect of moisture and electrostatic charges on powder flow, A. Rescaglio, J. Schockmel, N. Vandewalle and G. Lumay, EPJ Web of Conferences 140, 13009 (2017).
  • Compaction dynamics of a magnetized powder, G. Lumay, S. Dorbolo and N. Vandewalle, Physical Review E 80, 041302 (2009).
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About GranutoolsImage Credit: Granutools

GranuTools, is a company that improves powder understanding by delivering leading edge physical characterization tools.

“All we do is powder flow characterization”

A Set of Complementary Tools

Combining decades of experience in scientific instrumentation with fundamental research on powders characterization, we offer a unique set of complementary instruments for granular materials characterization.

Named after their purpose, our instruments are tools to understand macroscopic behavior of powders.

GranuFlow for flow, GranuHeap for static cohesion, GranuDrum for dynamic cohesion, GranuPack for tapped density and GranuCharge for triboelectric charge measurements are designed with the following in mind:

  • Precise & Repeatable
  • Automatic
  • No Operator Dependency
  • Robust & Easy to Use
  • Clear Interpretation

Last updated: Feb 16, 2023 at 9:57 AM

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