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How weather affects COVID-19 in India

With India now having endured six months of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there are now over 410,000 official cases in and more than 13,000 deaths recorded. Almost all these deaths have occurred in the last three months, April to June, with 100 deaths on April 4, 2020, increasing almost 16-fold by May 4, and 63-fold by June 4, 2020.

21 Jun 2020

SARS-CoV-2 saliva testing that omits the RNA extraction step

Even as the COVID-19 pandemic progresses throughout the world, the lack of consistent diagnostic testing has been a bugbear, preventing public health control of the spread of infection. A new study by researchers at the University of Illinois Urbana-Champaign and published on the preprint server bioRxiv in June 2020 reports a new testing method that uses saliva, does not require RNA extraction, and can be scaled up quickly and inexpensively.

21 Jun 2020

Massive proteomics investigation of COVID-19 infection

Researchers from Germany and Switzerland revealed functional effects of individual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins on cellular level after infection. They placed the findings into the context of host signaling pathways in order to identify vulnerable parts of the virus amenable to treatment. The study is currently available on the bioRxiv preprint server.

21 Jun 2020

A highly sensitive and specific antibody test for COVID-19

A new proof-of-concept study by UK researchers, currently available on the medRxiv* preprint server, describes the development of an enzyme-linked immunosorbent assay that can be used when lower levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific-antibodies are present in serum and saliva samples.

21 Jun 2020

Research explores the biophysical behavior of SARS-CoV-2 nucleocapsid protein

In a groundbreaking paper currently available on the bioRxiv* preprint server, the researchers from the Washington University School of Medicine and Stony Brook University showed how nucleocapsid protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is dynamic, disordered and phase separates with RNA – informing, in turn, the discovery of drugs that disrupt viral packaging.

21 Jun 2020

Interesting study on which species may be infected by SARS-CoV-2

The team from the University of Cambridge and the Pirbright Institute found that the Spike protein on SARS-CoV-2 engages with the host cell receptor angiotensin-converting enzyme 2 (ACE2) across a wide range of animals, even though the Spike binding site shows a between-species variation in its amino acid composition.

21 Jun 2020

Promising candidate monoclonal antibodies show "exquisite potency" against SAR-CoV-2

Researchers at Columbia University, Dana-Farber Cancer Institute, and the National Institutes of Health have identified and characterized a range of monoclonal antibodies that potently neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

21 Jun 2020

Environmental conditions affect the stability of SARS-CoV-2, study finds

A new study led by Marshall University researcher M. Jeremiah Matson found that environmental conditions affect the stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human nasal mucus and sputum.

21 Jun 2020

Infants tested positive for COVID-19 mostly have mild illness with fever

A report from Ann & Robert H. Lurie Children's Hospital of Chicago shows that infants under 90 days of age who tested positive for COVID-19 tend to be well, with little or no respiratory involvement. Fever was often found to be the primary or only symptom.

21 Jun 2020

Study finds widespread support for public health measures to limit spread of COVID-19

No mass gatherings. Stay-at-home orders. Nonessential business closures. Use of cloth face coverings. In April, these and other measures were adopted by states to try to mitigate the spread of COVID-19 in the U.S. and across the globe.

21 Jun 2020

New book shows meditation can reduce conflict and divisions in society

The COVID-19 pandemic has put societies everywhere under extreme stress, and collective stress is often a precursor to outbreaks of violence. Striking features of this global health crisis have been the collective anxiety of the population, the wide variations in the way governments have responded, and the varying degree of their success.

21 Jun 2020

Systems approach needed to address challenges of globally interconnected food system

Global food production is incredibly efficient, and the world's farmers produce enough to feed the global population.

21 Jun 2020

The underlying cause of ethnic differences in COVID-19 remains unexplained

Higher rates of severe COVID-19 infections in Black, Asian and Minority Ethnic (BAME) populations are not explained by socioeconomic or behavioral factors, cardiovascular disease risk, or by vitamin D status, according to new research led by Queen Mary University of London.

21 Jun 2020

Drama-based resources help Kingston University nursing students to cope with coronavirus pandemic

A set of drama-based resources to help Kingston University, London nursing students working during the Covid-19 pandemic have been put together through a collaboration with world-leading performing arts school Guildhall School of Music & Drama, London.

21 Jun 2020

Direct structural link between SARS-CoV-2 and essential fatty acid

Now, a new study published on the preprint server bioRxiv in June 2020 reports the discovery of a novel free fatty acid (FFA) binding pocket on the SARS-CoV-2 virus that could explain in part the viral effects of hyperinflammation, immune modulation, and membrane structure.

21 Jun 2020

Balanced B and T cell response required to control SARS-CoV-2

A new study by researchers in the Netherlands and published on the preprint server bioRxiv in June 2020 describes the differences in T and B cell responses seen in patients with severe COVID-19.

21 Jun 2020

One in four UK adults experiencing food insecurity during COVID-19 pandemic

One in four adults in the UK are experiencing food insecurity, which is likely to have left them susceptible to hunger and potential malnutrition, during the COVID-19 pandemic.

20 Jun 2020

New adjuvant helps induce long-lasting immunity against HIV

Researchers at the Yerkes National Primate Research Center and the Emory Vaccine Center (EVC) are first to show a new adjuvant, 3M-052, helps induce long-lasting immunity against HIV.

20 Jun 2020

COVID-19 plasma therapy safe and improves survival, says large study

Researchers working on COVID-19 therapy with plasma from convalescent patients have found that it is safe and effective and improves the chances of survival among those who are severely ill. The new study titled, “Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients,” is published as a preprint for the journal Mayo Clinic Proceedings.

20 Jun 2020

Italy’s sewage water shows SARS-CoV-2 present prior to reported outbreak in Wuhan

Italian researchers have found traces of the novel coronavirus SARS-CoV-2 in sewage wastewater that indicates that the virus may have been in circulation since December 2019. This controversial discovery shows that even before the first case was reported in Wuhan, China, in late December 2019, the virus had already arrived in northern Italy.

20 Jun 2020