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Sensor based on quantum effects may offer faster and accurate detection of SARS-CoV-2 virus

A novel approach to testing for the presence of the virus that causes Covid-19 may lead to tests that are faster, less expensive, and potentially less prone to erroneous results than existing detection methods. Though the work, based on quantum effects, is still theoretical, these detectors could potentially be adapted to detect virtually any virus, the researchers say.

21 Dec 2021

Two-dose ChAdOx1 vaccine protection wanes after three months

New research reported in the journal The Lancet examines the temporal association between the two-dose ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccination regimen and the risk of severe outcomes from COVID-19 in Scotland vs. Brazil, where the Delta variant of SARS-CoV-2 was dominant and rare, respectively.

21 Dec 2021

NIH’s new report provides a road map on how to improve Americans’ oral health

Despite important advances in the understanding and treatment of oral diseases and conditions, many people in the U.S. still have chronic oral health problems and lack of access to care, according to a report by the National Institutes of Health.

21 Dec 2021

Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

A new preprint research paper posted to the bioRxiv* server examines the nature and effects of the spike mutations and identifies a vulnerable point that could help develop broad-spectrum protection against circulating variants.

21 Dec 2021

National U.S trial confirms effectiveness of mRNA COVID-19 vaccines

In a recent study, published in the Annals of Internal Medicine, scientists conducted a target trial emulation study and documented that among the elderly in the U.S. (with significant comorbidities), the efficacy of messenger RNA (mRNA) vaccines was much lower in terms of preventing infection, than previously reported. However, the effectiveness against death was found to be high.

21 Dec 2021

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

Comparison of SARS-CoV-2 rapid antigen tests

Researchers test commercially rapid antigen tests to evaluate their analytical sensitivity and specificity, as well as clinical sensitivity for detecting SARS-CoV-2.

21 Dec 2021

Early administration of SARS-CoV-2 convalescent plasma reduces outpatient hospitalizations

The results of a nationwide, multicenter clinical trial led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health provides solid evidence for the use of plasma from convalescent patients — those who have recovered from the disease and whose blood contains antibodies against SARS-CoV-2, the virus that causes COVID-19 — as an early treatment.

21 Dec 2021

Risk of exposure to SARS-CoV-2 by workplace and trade

Researchers investigate the risk of SARS-CoV-2 exposure to people in workplaces across different occupations over time.

21 Dec 2021

How the SARS-CoV-2 Omicron variant spike protein is changing

The study assesses the degree to which the D614G mutation in the SARS-CoV-2 RBD allows access of spike protein trimers to LA-binding-like conformations.

21 Dec 2021

Comparison of point-of-care SARS-CoV-2 diagnostic kits

A multinational group of scientists investigates the performance characteristics of several point-of-care diagnostic kits for SARS-CoV-2.

21 Dec 2021

What are the long-term effects of COVID-19 on mental health?

Researchers determine the long-term adverse mental health symptoms associated with COVID-19 by estimating acute infection severity.

21 Dec 2021

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

Researchers investigate the possible relationship between COVID-19 vaccination and the incidences of Guillain-Barre syndrome.

21 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Researchers determined IgG titers of vaccinated healthcare workers 11 months following primary COVID-19 vaccination.

21 Dec 2021

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

A new study demonstrates significantly altered structure and cellularity of Peyer’s patches in deceased COVID-19 patients.

21 Dec 2021

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

A new study aimed to detect the genomic material of SARS-CoV-2 and its variants, such as the recently emerged variant of concern (VOC) Omicron.

21 Dec 2021

Effect of T cell reactivity in COVID-19 infection and vaccination

Researchers recently developed an immunodiagnostic T cell assay to classify T cell immune responses of the subjects based on their coronavirus disease 2019 infection and vaccination history.

21 Dec 2021

Do reactive oxygen species play a role in fighting COVID-19?

Serum-free thiols are known to reflect the activity of reactive oxygen species in the body, and researchers have been examining the difference in these thiols in COVID-19 patients.

21 Dec 2021

Crude infection fatality rate is a key indicator in understanding COVID-19 mortality

Researchers leveraged recent data sources and broadly applicable modeling strategies to calculate the COVID-19 crude infection fatality rate (cIFR) in 77 countries from 28 March 2020 to 31 March 2021

21 Dec 2021

SARS News and Research

Sensor based on quantum effects may offer faster and accurate detection of SARS-CoV-2 virus

Two-dose ChAdOx1 vaccine protection wanes after three months

NIH’s new report provides a road map on how to improve Americans’ oral health

Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

National U.S trial confirms effectiveness of mRNA COVID-19 vaccines

Promising new drug target for TB identified

Comparison of SARS-CoV-2 rapid antigen tests

Early administration of SARS-CoV-2 convalescent plasma reduces outpatient hospitalizations

Risk of exposure to SARS-CoV-2 by workplace and trade

How the SARS-CoV-2 Omicron variant spike protein is changing

Comparison of point-of-care SARS-CoV-2 diagnostic kits

What are the long-term effects of COVID-19 on mental health?

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

Molecular mechanism of SARS-Cov-2-induced thrombosis

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

Effect of T cell reactivity in COVID-19 infection and vaccination

Do reactive oxygen species play a role in fighting COVID-19?

Crude infection fatality rate is a key indicator in understanding COVID-19 mortality

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