Disease/Infection News

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Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

A team of scientists from the USA and France has recently unveiled the mechanism of immune dysregulation in coronavirus disease 2019 (COVID-19) patients by analyzing the early-stage interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected epithelial cells and immune cells. The study is currently available on the bioRxiv* preprint server.

30 Sep 2021

The connection between age and virulence of SARS-CoV-2 variants of concern

A new study focuses on determining the existence of an age-related heterogeneity in the severity of COVID-19.

30 Sep 2021

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

French researchers used a highly sensitive and specific nucleocapsid-Ag assay to explore the relationship between N-Ag in urine during COVID-19 and the severity of the disease in hospitalized patients.

30 Sep 2021

Study investigates long-COVID symptoms in people recovering from COVID-19 infection

This new study from the University of Oxford and the National Institute for Health Research (NIHR) Oxford Health Biomedical Research Centre (BRC) investigated long-COVID in over 270,000 people recovering from COVID-19 infection, using data from the US-based TriNetX electronic health record network.

30 Sep 2021

New drug combination effectively suppresses SARS-CoV-2 infection

More countries with greater resources are opening up for a more normal life. But COVID-19 and the SARS-CoV-2 virus are still a significant threat in large parts of the world.

30 Sep 2021

The applications of nanomaterials against viral disease

The application of nanomaterials in the diagnosis, prevention, and treatment of viral diseases is reviewed in detail, highlighting areas of significant progress or stagnation from the past few decades.

30 Sep 2021

Diverse vaccine attitudes amongst UK healthcare workers suggest hesitancy may remain after vaccine acceptance

In a recent paper, the phenomenon of vaccine hesitancy is further explored amongst UK healthcare workers.

30 Sep 2021

ACTG to present data highlighting a new therapeutic for COVID-19 at the virtual IDWeek 2021

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that Teresa H. Evering, M.D., M.S., a co-lead investigator (with Eric S. Daar, M.D.) for BRII-196/BRII-198 in the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies, will present data for the monoclonal antibody combination at the virtual IDWeek 2021 conference, taking place September 29 – October 3, 2021.

30 Sep 2021

SARS-CoV-2 infection aided by antibody-dependent enhancement

The coronavirus disease 2019 (COVID-19) pandemic has raised concerns about the detrimental effects of antibodies. Antibody-dependent enhancement (ADE) of infection is one of the biggest concerns in terms of not only the antibody reaction to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon reinfection with the virus but also the reaction to COVID-19 vaccines.

30 Sep 2021

Instrument to measure risk of reverse zoonotic SARS-CoV-2 transmission events from humans to animals

A new study published on the medRxiv* preprint server presents a standardized survey instrument for evaluating risk factors associated with bidirectional zoonotic transmission of SARS-CoV-2 and pathogens. The instrument is particularly focused on settings where humans and animals share close contact.

30 Sep 2021

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Now, in a new news study posted to the bioRxiv* preprint server, researchers have successfully induced similar chronicity associated with SARS-CoV-2 infection in MISTRG6-hACE2 humanized mice.

29 Sep 2021

Novel framework can predict changes that may increase the infectiousness of SARS-CoV-2

As SARS-CoV-2 continues to evolve, new variants are expected to arise that may have an increased ability to infect their hosts and evade the hosts' immune systems.

29 Sep 2021

Research gauges reductions in the quality of life during COVID-19

The results of a survey were published on the medRxiv* preprint server, the purpose of which was to assess the relative well-being of the population under Covid-19 restrictions – through 952 survey respondents from France, India, Italy, the UK, and the US.

29 Sep 2021

Scientists offers new hope for future treatment of sepsis

Sepsis, the body's life-threatening response to infection affecting about 1.7 million adults in the United States each year, can lead to multisystem organ failure with a high mortality rate.

29 Sep 2021

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

A new study aimed to determine the course of SARS-CoV-2 infection in children suffering from rheumatic disease and were receiving bDMARD treatment.

29 Sep 2021

Immunocompromised patients show decreased response to SARS-CoV-2 mRNA vaccines

Researchers explore the germinal cell responses in both healthy individuals and kidney transplant patients in their recent study.

29 Sep 2021

Study finds strong evidence of transplacental passage of IgG antibodies following COVID vaccination

In the current study, researchers investigate the transplacental transmission of antibodies in vaccinated pregnant women.

29 Sep 2021

A review of COVID-19 vaccine effectiveness

A new study systematically reviews vaccine efficacy and vaccine effectiveness (VE) of COVID-19 vaccines.

29 Sep 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

Study investigates the mechanism underlying kidney damage in COVID-19 patients

A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo in Brazil discusses the mechanisms whereby SARS-CoV-2 damages the kidneys, potentially serving as a basis for further research in pursuit of treatments to prevent severe renal problems and even chronic kidney disease in COVID-19 patients.

29 Sep 2021

Disease/Infection News

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

The connection between age and virulence of SARS-CoV-2 variants of concern

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

Study investigates long-COVID symptoms in people recovering from COVID-19 infection

New drug combination effectively suppresses SARS-CoV-2 infection

The applications of nanomaterials against viral disease

Diverse vaccine attitudes amongst UK healthcare workers suggest hesitancy may remain after vaccine acceptance

ACTG to present data highlighting a new therapeutic for COVID-19 at the virtual IDWeek 2021

SARS-CoV-2 infection aided by antibody-dependent enhancement

Instrument to measure risk of reverse zoonotic SARS-CoV-2 transmission events from humans to animals

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Novel framework can predict changes that may increase the infectiousness of SARS-CoV-2

Research gauges reductions in the quality of life during COVID-19

Scientists offers new hope for future treatment of sepsis

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

Immunocompromised patients show decreased response to SARS-CoV-2 mRNA vaccines

Study finds strong evidence of transplacental passage of IgG antibodies following COVID vaccination

A review of COVID-19 vaccine effectiveness

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

Study investigates the mechanism underlying kidney damage in COVID-19 patients

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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