Cytokines News and Research

Latest Cytokines News and Research

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future?

15 Apr 2021

Ponatinib identified as a potent inhibitor of SARS-CoV2-induced cytokine storm

Researchers at the Human Biology Division, Fred Hutchinson Cancer Research Center in Washington, United States, found that the FDA-approved, multi-kinase inhibitor Ponatinib is a potent inhibitor of the N-terminal domain (NTD) -mediated cytokine storm. Ponatinib is an oral drug used for the treatment of chronic myeloid leukemia (CML).

14 Apr 2021

Researchers investigate link between COVID-19 and increased risk of blood clot formation

People who have recovered from COVID-19, especially those with pre-existing cardiovascular conditions, may be at risk of developing blood clots due to a lingering and overactive immune response, according to a study led by Nanyang Technological University, Singapore (NTU) scientists.

13 Apr 2021

Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins

A clinical trial testing the safety and efficacy of an investigational monoclonal antibody for treating people who are hospitalized with respiratory disease and low blood oxygen due to infection with SARS-CoV-2, the virus that causes COVID-19, has begun.

13 Apr 2021

Which SARS-CoV-2 spike mutants can evade T cell immunity?

A new study reports the capability of a new variant of the virus to escape specific cellular immunity, while possessing a higher binding affinity to the host cell binding receptor, the angiotensin-converting enzyme 2 (ACE2).

7 Apr 2021

SARS-CoV-2 inhibits the cellular response to interferon

Researchers have explored the effect of SARS-CoV-2 infection on the function of RIG-I and MDA5, and ultimately on interferon production.

31 Mar 2021

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.

31 Mar 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Vaccine-induced 2C08 antibody protects against SARS-CoV-2 variants

A new preprint study posted to the bioRxiv* server led by Ali H. Ellebedy from the Washington University School of Medicine found that the monoclonal antibody 2C08 produced by the Pfizer vaccine could help neutralize COVID-19 variants.

29 Mar 2021

Corticosteroid therapy in pregnant women with COVID-19

A new study describes the outcome of corticosteroid use in pregnancy.

29 Mar 2021

New therapeutic vaccine uses patient's own tumor cells to aid in cancer destruction

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

24 Mar 2021

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Through an analysis of cellular components (cell fractions) from malignant ascites (fluid buildup in the abdomen caused by gastric cancer), a research collaboration based in Kumamoto University (Japan) has demonstrated that cellular senescence of cancer-associated fibroblasts (CAFs) play an important role in the peritoneal dissemination of gastric cancer foci (cells different from surrounding cells).

23 Mar 2021

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

Serious complications due to blood clots, such as heart attacks and strokes, that are experienced by some COVID-19 survivors may be caused by a lingering immune response in the blood vessels after recovery, suggests a study published today in eLife.

23 Mar 2021

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Although Tuberculosis, or TB, killed nearly as many people as COVID-19 (approx. 1.8 million) in 2020, it did not receive as much media and public attention.

22 Mar 2021

SARS-CoV-2 variants develop resistance against type I interferons

A study conducted at the University of Colorado and National Institutes of Health, USA, has revealed that the resistance developed by newly emerging variants of SARS-CoV-2 against host interferon responses could serve as a potential driving force for viral evolution.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

The triggers and causes of a severe scarring disease of the lungs -- idiopathic pulmonary fibrosis, or IPF -- remain unclear.

18 Mar 2021

Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases, linked to the University of São Paulo in Brazil, discovered a novel path in the inflammatory process associated with the bone damage caused by rheumatoid arthritis.

18 Mar 2021

Study reveals unknown immune defense system that protects the lungs from viral infections

Researchers have uncovered a previously unknown arm of the immune defence system that protects the lung from lethal viral infections.

18 Mar 2021

Cytokines News and Research

Latest Cytokines News and Research

Study identifies differences in biomarkers of inflammation between novel diabetes subgroups

Ponatinib identified as a potent inhibitor of SARS-CoV2-induced cytokine storm

Researchers investigate link between COVID-19 and increased risk of blood clot formation

Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins

Which SARS-CoV-2 spike mutants can evade T cell immunity?

SARS-CoV-2 inhibits the cellular response to interferon

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

Vaccine-induced 2C08 antibody protects against SARS-CoV-2 variants

Corticosteroid therapy in pregnant women with COVID-19

New therapeutic vaccine uses patient's own tumor cells to aid in cancer destruction

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

SARS-CoV-2 variants develop resistance against type I interferons

Male fertility and androgen production may be impacted by COVID-19

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

Study reveals unknown immune defense system that protects the lungs from viral infections

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Cytokines News and Research

Latest Cytokines News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in