Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Very few COVID-19-positive children require hospitalization, finds case study

A team of researchers at the Divisions of Infectious Diseases, UPMC Children’s Hospital of Pittsburgh and the University of Pittsburgh, USA, sought to characterize the clinical presentation of children with COVID-19 in Western Pennsylvania.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Can online health forums track the effect of COVID-19 on mental health?

A team of researchers at King's College London, UK, and other institutions used publicly accessible sources of real-world data, such as online health forums. They found that authors of COVID-19 related posts most frequently mentioned mental health symptom keywords during the first wave, followed by physical symptoms and intensive care keywords.

18 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

A new paper describes the development and validation of a rapid test to measure the neutralizing activity of serum against COVID-19 using a drop of blood.

18 Dec 2020

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A new multicenter study has shown that blinded crossover and continued follow-up of trial participants can help assess vaccine durability and potential delayed enhancement of disease.

18 Dec 2020

Experts to share the lessons learnt from COVID-19 first wave

The Physiological Society and the Intensive Care Society have come together to host an exciting three-day virtual conference this week, which will review the challenges of understanding the pathophysiological changes occurring throughout the body following COVID-19 infection.

18 Dec 2020

Continued vigilance is required in England following exit from second lockdown

Researchers in the UK have presented data from the latest in a series of community surveys assessing the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in England.

17 Dec 2020

New prognostic tool predicts the need for ICU among COVID-19 patients

Researchers in the UK have developed a prognostic tool that accurately predicts whether patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent causes coronavirus disease 2019 (COVID-19) – will require admission to the intensive care unit (ICU), die, or survive without escalation to ICU.

17 Dec 2020

How does the UK’s COVID-19 response compare to others in Europe?

Researchers modeled the health benefits and economic loss caused by coronavirus disease 2019 (COVID-19) in the UK and compared them to four other western European countries. Their results suggest the British Government’s response may outweigh the economic loss incurred.

17 Dec 2020

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

A new study by researchers at the Karolinska University Hospital in Sweden shows that testing for the presence of SARS-CoV-2 nucleic acid can help in containing the virus spread. Detecting the presence of high amounts of SARS-CoV-2 nucleic acid predicts future symptomatic disease, they found.

17 Dec 2020

No added risks to radiation therapy for cancer patients with COVID-19, says study

A team of radiation oncologists at the Zucker School of Medicine at Hofstra/Northwell in the United States aimed to determine if COVID-19 infected cancer patients receiving radiation therapy (RT) have any different outcome than non-infected patients.

17 Dec 2020

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

A preprint indicates that SARS-CoV-2 requires cholesterol to accomplish entry into the host cells and membrane fusion.

17 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

A recent preprint that appeared on the bioRxiv* server applies a new approach to conventional birth-death lineage modeling.

17 Dec 2020

SARS-CoV-2 spike deletion ΔH69/ΔV70 shows repeated emergence and spread

Since the COVID 19 pandemic, it has been established that the causative virus, SARS-CoV-2 gains entry to the target host cell via its spike glycoprotein.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

SARS-CoV-2 has infected over 71.5 million people and claimed over 1.6 million lives globally since December 2019.

17 Dec 2020

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Researchers demonstrated that neuroinvasion and encephalitis caused by SARS-CoV-2 is associated with significant mortality in a special mouse model.

17 Dec 2020

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

As researchers continue to search for antivirals to counter COVID-19, a study presents the potential utility of a decoction called Respiratory Detox Shot (RDS).

16 Dec 2020

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Very few COVID-19-positive children require hospitalization, finds case study

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Can online health forums track the effect of COVID-19 on mental health?

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

Experts to share the lessons learnt from COVID-19 first wave

Continued vigilance is required in England following exit from second lockdown

New prognostic tool predicts the need for ICU among COVID-19 patients

How does the UK’s COVID-19 response compare to others in Europe?

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

No added risks to radiation therapy for cancer patients with COVID-19, says study

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

SARS-CoV-2 spike deletion ΔH69/ΔV70 shows repeated emergence and spread

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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