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An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

A new study was based on the hypothesis that competitively inhibiting cellular furin and selectively targeting SARS-CoV-2 in the infected viral-producing cells is critical for therapeutic specificity.

14 Feb 2022

Study explores the social impact of COVID-19 symptoms among female long haulers

A new study analyzed the impact of long-COVID on women long haulers with respect to various aspects of their social life.

14 Feb 2022

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

A new study describes a new method to quantify SARS-CoV-2 infection, which is much simpler and faster compared to existing methods.

14 Feb 2022

Study finds mRNA vaccines induce poor neutralizing antibody response against SARS-CoV-2 variants in dialysis patients

Scientists studied plasma samples from 130 hemodialysis (HD) and 13 peritoneal dialysis patients and showed a poor neutralizing and rapidly decaying antibody response to mRNA vaccines in such individuals.

14 Feb 2022

How a third booster BNT162b2 dose impacts anti-spike antibody levels

A new study aimed to investigate the mechanism by which the third booster BNT162b2 dose impacts anti-S levels.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

In a recent study posted to Preprints with The Lancet* server, a team of researchers from China performed a serology study of thyroid function and antithyroid antibody levels in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-vaccinated recipients and further evaluated their correlation with SARS-CoV-2 neutralizing antibodies (NAbs) levels.

14 Feb 2022

Nitazoxanide shows promise for COVID-19 treatment in animal model

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that Nitazoxanide (NTZ), an oral drug, broadly inhibits replication of several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in preclinical models of infection.

13 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Wearable sensors for COVID-19 mitigation

In a recent study posted to the medRxiv* pre-print server, researchers simulated several wearable sensor deployment scenarios to demonstrate the potential of digital contact tracing technology in mitigating the coronavirus disease 2019 (COVID-19) pandemic.

13 Feb 2022

Study shows IgA antibodies play a significant role in neutralizing SARS-CoV-2

A recent paper by researchers from Australia, currently available on the medRxiv* preprint server, shows how Immunoglobulin A (IgA) antibodies in individuals who were infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to the neutralization of the virus and its variants, even though this response is heterogeneous and less potent when compared to IgG antibodies.

13 Feb 2022

Looking into the long-COVID brain

Neurological issues, ranging from memory lapses to trouble with attention, have been widely reported after recovery from severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection. Unfortunately, there is limited information about pathways to recovery after severe COVID hospitalization. Now, a prospective study of 4,491 patients hospitalized with COVID suggests neurological recovery can take at least a year. The study is currently available on the medRxiv* preprint while awaiting peer review.

13 Feb 2022

Assessing potential allergic reactions in COVID-19 vaccinated patients

Researchers analyze suspected reactions in patients vaccinated with the first and/or second dose of SARS-CoV-2 vaccines.

13 Feb 2022

Real world evidence on acquired immunity from vaccines and SARS-CoV-2 infection

Researchers assess the incidence of SARS-CoV-2 breakthrough cases and reinfections among unvaccinated and vaccinated individuals.

13 Feb 2022

Study examines the viral dynamics of Hong Kong's four SARS-CoV-2 waves

Researchers evaluate the efficiency of COVID-19 elimination strategies implemented in Hong Kong.

13 Feb 2022

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

A new study provided the structural basis for a robust interaction between the receptor-binding domain of the SARS-CoV-2 Omicron spike protein and mouse ACE2.

13 Feb 2022

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

MUSC Hollings Cancer Center researcher Sophie Paczesny, M.D., Ph.D., recently received a four-year grant from the National Heart, Lung, and Blood Institute to investigate solutions to help doctors to fight complications after pediatric bone marrow transplantation (BMT).

12 Feb 2022

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

A study in mice -; led by researchers at Washington University School of Medicine in St. Louis -; shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome.

12 Feb 2022

Study points to vagus nerve dysfunction as a central pathophysiological feature of long COVID

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) suggests that many of the symptoms connected to post-COVID syndrome (PCC, also known as long COVID) could be linked to the effect of the virus on the vagus nerve – one of the most important multi-functional nerves in the body.

12 Feb 2022

Sleep apnea during pregnancy linked to the development of hypertension and metabolic syndrome

In a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, researchers examined whether sleep disordered breathing (primarily obstructive sleep apnea) during pregnancy and in the years after delivery is associated with an increased risk for hypertension and metabolic syndrome.

12 Feb 2022

Syndrome News and Research

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

Study explores the social impact of COVID-19 symptoms among female long haulers

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

Study finds mRNA vaccines induce poor neutralizing antibody response against SARS-CoV-2 variants in dialysis patients

How a third booster BNT162b2 dose impacts anti-spike antibody levels

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

Nitazoxanide shows promise for COVID-19 treatment in animal model

Testes found to be a viral reservoir for SARS-CoV-2 replication

Wearable sensors for COVID-19 mitigation

Study shows IgA antibodies play a significant role in neutralizing SARS-CoV-2

Looking into the long-COVID brain

Assessing potential allergic reactions in COVID-19 vaccinated patients

Real world evidence on acquired immunity from vaccines and SARS-CoV-2 infection

Study examines the viral dynamics of Hong Kong's four SARS-CoV-2 waves

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

Study points to vagus nerve dysfunction as a central pathophysiological feature of long COVID

Sleep apnea during pregnancy linked to the development of hypertension and metabolic syndrome

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