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Survey: CDC's opioid prescribing guideline for pain treatment should be revoked

The CDC's opioid prescribing guideline has failed to reduce addiction and overdoses, significantly worsened the quality of pain care in the United States and should be revoked, according to a large new survey of patients and healthcare providers by Pain News Network, an independent, non-profit news organization.

26 Apr 2021

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

People who take a commonly-prescribed drug for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, after a large-scale study found many had poor antibody responses.

26 Apr 2021

Novel non-opioid approach to relieve pain after knee surgery

A new study by Henry Ford Health System published in Arthroscopy: The Journal of Arthroscopic and Related Surgery may signal a first step toward eliminating the use of opioids to relieve pain after knee surgery.

26 Apr 2021

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

One of these vaccines, the Ad26.COV2.S vaccine by Johnson & Johnson and Janssen, is a recombinant, replication-incompetent human adenovirus type 26 vector that encodes full-length SARS-CoV-2 spike protein in a prefusion-stabilized conformation.

26 Apr 2021

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

A new multidisciplinary study from Australia, published in the open-access journal mBio, shows that three compounds used to treat cystic fibrosis, dry eye, and a specific medical dye may lead to future strategies for the treatment of coronavirus disease (COVID-19).

25 Apr 2021

Study sheds light on the ability of CBD to reduce pain

It's been hailed as a wonder drug and it's certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could be worth $20 billion dollars by 2024.

23 Apr 2021

FDA, CDC lift recommended pause on the use of Janssen COVID-19 vaccine in the U.S.

Following a thorough safety review, including two meetings of the CDC's Advisory Committee on Immunization Practices, the U.S. Food and Drug Administration and the U.S. Centers for Disease Control and Prevention have determined that the recommended pause regarding the use of the Johnson & Johnson (Janssen) COVID-19 Vaccine in the U.S. should be lifted and use of the vaccine should resume.

23 Apr 2021

Study reports on safety of COVID-19 mRNA vaccines in pregnancy

Researchers used different surveillance systems in the United States to track adverse outcomes after coronavirus disease 2019 (COVID-19) vaccination in pregnant people and found no major safety flags.

23 Apr 2021

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

The National Institutes of Health (NIH) in the USA are to conduct a large-scale clinical trial to evaluate a new fully-human polyclonal antibody therapy targeted at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Apr 2021

New study demonstrates the effectiveness of COVID-19 vaccine in specific sub-populations

Several weeks following the publication of the large real-world Covid-19 vaccine effectiveness study by the Clalit Research Institute in Collaboration with Harvard University in the New England Journal of Medicine (NEJM), additional results focusing on vaccine effectiveness in specific sub-populations have now been published.

23 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

National registry needs to be set up for capturing pharma industry payments to clinicians and patient support groups

A national registry to capture all pharma/medical device industry payments and other benefits made to all clinicians, healthcare organizations and patient support groups should be set up as a matter of urgency in the UK, insists an editorial in the Drug and Therapeutics Bulletin (dtb).

22 Apr 2021

Patients with high HIV risk are aware of preventative pill, but few are using it

Cisgender sexual minority men and transgender women are aware of pre-exposure prophylaxis (PrEP), a daily pill for HIV-negative people to prevent HIV infection, but few are currently taking it, according to researchers at Rutgers.

22 Apr 2021

Shifts in care due to COVID-19 pandemic likely to drive drug expenditures in 2021

The COVID-19 pandemic heavily influenced spending on prescription drugs in the U.S. in 2020, according to the ASHP's (American Society of Health-System Pharmacists) National Trends in Prescription Drug Expenditures and Projections for 2021.

21 Apr 2021

People who regularly use psychoactive substances experienced negative impacts during COVID-19

People who regularly use psychoactive substances report experiencing a variety of negative impacts since the COVID-19 pandemic began, including increased usage and fear of relapse or overdose, highlighting the need for improved supports and services, including better access to safe supply programs, according to a new CAMH survey published in the International Journal of Drug Policy.

21 Apr 2021

Policies designed to prevent opioid misuse may limit access to pain-relieving drugs

Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

Despite global efforts, allocation and distribution of COVID-19 vaccines are not equitable

Ensuring COVID-19 vaccine access for refugee and displaced populations, and addressing health inequities, is vital for an effective pandemic response.

20 Apr 2021

Screening drug candidates for COVID-19 treatment using computational methods

Researchers identified two potential drug candidates that can inhibit SARS-CoV-2 in vitro. Their combination can work synergistically and increase their inhibitory effect.

19 Apr 2021

Study shows adverse outcomes associated with use of more blood thinners

More blood thinners aren't automatically better, another study confirms. A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.

19 Apr 2021

Pharmaceutical News

Survey: CDC's opioid prescribing guideline for pain treatment should be revoked

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

Novel non-opioid approach to relieve pain after knee surgery

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

Study sheds light on the ability of CBD to reduce pain

FDA, CDC lift recommended pause on the use of Janssen COVID-19 vaccine in the U.S.

Study reports on safety of COVID-19 mRNA vaccines in pregnancy

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

New study demonstrates the effectiveness of COVID-19 vaccine in specific sub-populations

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

National registry needs to be set up for capturing pharma industry payments to clinicians and patient support groups

Patients with high HIV risk are aware of preventative pill, but few are using it

Shifts in care due to COVID-19 pandemic likely to drive drug expenditures in 2021

People who regularly use psychoactive substances experienced negative impacts during COVID-19

Policies designed to prevent opioid misuse may limit access to pain-relieving drugs

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Despite global efforts, allocation and distribution of COVID-19 vaccines are not equitable

Screening drug candidates for COVID-19 treatment using computational methods

Study shows adverse outcomes associated with use of more blood thinners

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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