Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Comparison of RBD/ACE2 receptor complex in wild type SARS-CoV-2 and Omicron variant

New research details the molecular landscape of Omicron’s RBD and how it differs from the original SARS-CoV-2 strain.

17 Dec 2021

New study demonstrates SARS-CoV-2 Omicron antibody escape

A new study examined the neutralization of virus variants using three sets of antibodies: serum from individuals vaccinated or infected with earlier variants of the virus; concentrated human antibodies from plasma donors; and approved monoclonal antibodies.

16 Dec 2021

Moderna booster vaccination overcomes SARS-CoV-2 Omicron variant antibody escape

A new study reports the results of a study focused on immune evasion characteristics, specifically the ability to escape neutralization by antibodies to the earlier SARS-CoV-2 variants or to the spike antigen used in COVID-19 vaccines.

16 Dec 2021

Study suggests convalescent plasma appears safe but does not prevent SARS-CoV-2 infection

A new study assesses the safety and efficacy of SARS-CoV-2 convalescent plasma containing high titers of anti-SARS-CoV-2 antibodies as PEP.

16 Dec 2021

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

A new study found that the Omicron S protein evades antibodies with a 44-fold higher efficiency than the Delta variant's spike, rendering therapeutic antibodies ineffective and likely negatively impacting antibody protection induced by infection or double vaccination.

16 Dec 2021

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

The team observed that three doses of the BNT162b2 (Pfizer-BioNTech) mRNA vaccine are required to mount an effective antibody response against the Omicron variant.

16 Dec 2021

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

A new study highlights the significance of robust T cell responses in preventing severe omicron infections.

16 Dec 2021

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

A new study has used this assay to evaluate sera, obtained from 239 individuals vaccinated via any of the above-stated vaccines against SARS-CoV-2’s original strain, the Delta, and Omicron SARS-CoV-2 pseudoviruses.

16 Dec 2021

Human monoclonal antibody protects against SARS-CoV-2 and SARS-CoV in vivo

Scientists identified a human monoclonal antibody (mAb), which successfully neutralized or bound all sarbecoviruses tested in vitro.

16 Dec 2021

Exploring the plasma neutralization properties of the Omicron variant of SARS-CoV-2

A new study determines the ability of individuals with varying exposure to SARS-CoV-2 infection and vaccination, to neutralize SARS- CoV-2 pseudotypes.

16 Dec 2021

Study suggests Omicron can be neutralized by BNT162b2 recipient sera optimally after three vaccine doses

Researchers from Westmead Hospital have been investigating the effect of a third dose on neutralizing antibody titres in already vaccinated individuals.

16 Dec 2021

Vaccine effectiveness of mRNA-1273 during the emergence of the SARS-CoV-2 Delta variant

The authors highlight that their research confirms the effectiveness of two doses of mRNA-1273 against SARS-CoV-2 infection.

16 Dec 2021

Evaluation of SARS-CoV-2 neutralizing antibodies in mothers and infants

A new study assessed nAb activities against five strains of SARS-CoV-2 in paired maternal and infant cord blood samples.

15 Dec 2021

How SARS-CoV-2 affects the male reproductive system

Researchers review the potentially harmful consequences on the male reproductive system in COVID-19 patients.

15 Dec 2021

Evaluation of SARS-CoV-2 Omicron's immune evasion potential

Researchers use VSV vector and Omicron spike protein containing all 32 mutations to create the pseudotyped SARS-CoV-2 Omicron variant (PV-Omicron).

15 Dec 2021

Signatures of rising SARS-CoV-2 Delta infections in New York

Researchers estimate the probability of breakthrough infections by the Delta variant as compared to other variants.

15 Dec 2021

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers demonstrate that the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 require endogenous IFITM2 expression for efficient replication.

15 Dec 2021

New Canadian study shows how SARS-CoV-2 transmission occurred in schools

Researchers explore the frequency, cluster size, and transmission rate of COVID-19 in schools using a simple mathematical model.

15 Dec 2021

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

Researchers investigate the post-vaccination clonal T-cell response and its relationship to antibody responses in IBD patients.

15 Dec 2021

Factors associated with having data on SARS-CoV-2 infection and COVID-19 severity

Researchers utilized pre-pandemic information from two UK-based observational population studies to investigate predictors of selection into analytic subsamples in observational studies on SARS-CoV-2 infection and on COVID-19 severity.

15 Dec 2021

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Comparison of RBD/ACE2 receptor complex in wild type SARS-CoV-2 and Omicron variant

New study demonstrates SARS-CoV-2 Omicron antibody escape

Moderna booster vaccination overcomes SARS-CoV-2 Omicron variant antibody escape

Study suggests convalescent plasma appears safe but does not prevent SARS-CoV-2 infection

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

Human monoclonal antibody protects against SARS-CoV-2 and SARS-CoV in vivo

Exploring the plasma neutralization properties of the Omicron variant of SARS-CoV-2

Study suggests Omicron can be neutralized by BNT162b2 recipient sera optimally after three vaccine doses

Vaccine effectiveness of mRNA-1273 during the emergence of the SARS-CoV-2 Delta variant

Evaluation of SARS-CoV-2 neutralizing antibodies in mothers and infants

How SARS-CoV-2 affects the male reproductive system

Evaluation of SARS-CoV-2 Omicron's immune evasion potential

Signatures of rising SARS-CoV-2 Delta infections in New York

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

New Canadian study shows how SARS-CoV-2 transmission occurred in schools

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

Factors associated with having data on SARS-CoV-2 infection and COVID-19 severity

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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